Lysylated phospholipids stabilize models of bacterial lipid bilayers and protect against antimicrobial peptides

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 9, 2014, Pages 2198-2204

  Cox, Elizabeth ^a   Michalak, Austen ^a   Pagentine, Sarah ^a   Seaton, Pamela ^a   Pokorny, Antje ^a  

^a UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

Author keywords

Aminoacylated lipids; Amphipathic peptides; Antimicrobial peptides; Bacterial lipids; Headgroup modified bacterial lipids; Lysyl PG

Indexed keywords

1 PALMITOYL 2 OLEOYL PHOSPHATIDYLCHOLINE; 1 PALMITOYL 2 OLEOYL PHOSPHATIDYLGLYCEROL; CECROPIN A; GLUTAMINE; LYSINE; MASTOPARAN X; MICROORGANISM PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; PHOSPHOLIPID; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL MEMBRANE; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); LIPID BILAYER; LIPID VESICLE; LIPOGENESIS; MEMBRANE STABILIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LIPID INTERACTION; PROTEIN MODIFICATION; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

AMINOACYLATED LIPIDS; AMPHIPATHIC PEPTIDES; ANTIMICROBIAL PEPTIDES; BACTERIAL LIPIDS; HEADGROUP-MODIFIED BACTERIAL LIPIDS; LYSYL-PG;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; HUMANS; LIPID BILAYERS; LYSINE; PEPTIDES; PHOSPHATIDYLGLYCEROLS; PHOSPHOLIPIDS; STAPHYLOCOCCUS AUREUS;

EID: 84903697585     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.04.018     Document Type: Article

References (25)

1. W.M. OLeary, and S.G. Wilkinson Gram-positive bacteria C. Ratledge, S.G. Wilkinson, Microbial Lipids vol. 1 1988 Academic Press San Diego 117 201
2. A. Peschel, R.W. Jack, M. Otto, L.V. Collins, P. Staubitz, G. Nicholson, H. Kalbacher, W.F. Nieuwenhuizen, G. Jung, A. Tarkowski, K.P. van Kessel, and J.A. van Strijp Staphylococcus aureus resistance to human defensins and evasionof neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine J. Exp. Med. 193 2001 1067 1076 (Pubitemid 32436200)
3. H. Nishi, H. Komatsuzawa, T. Fujiwara, N. McCallum, and M. Sugai Reduced content of lysyl-phosphatidylglycerol in the cytoplasmic membrane affects susceptibility to moenomycin, as well as vancomycin, gentamicin, and antimicrobial peptides, in Staphylococcus aureus Antimicrob. Agents Chemother. 48 2004 4800 4807 (Pubitemid 39577687)
4. A. Rubio, J. Moore, M. Varoglu, M. Conrad, M. Chu, W. Shaw, and J.A. Silverman LC-MS/MS characterization of phospholipid content in daptomycin-susceptible and -resistant isolates of Staphylococcus aureus with mutations in mprF Mol. Membr. Biol. 29 2012 1 8
5. N.N. Mishra, and A.S. Bayer Correlation of cell membrane lipid profiles with daptomycin resistance in methicillin-resistant Staphylococcus aureus Antimicrob. Agents Chemother. 57 2013 1082 1085
6. P.F. Almeida, and A. Pokorny Interactions of antimicrobial peptides with lipid bilayers L. Tamm, Comprehensive Biophysics vol. 5 2012 Elsevier B. V. 189 222
7. S.A. Wheaten, F.D. Ablan, B.L. Spaller, J.M. Trieu, and P.F. Almeida Translocation of cationic amphipathic peptides across the membranes of pure phospholipid giant vesicles J. Am. Chem. Soc. 135 2013 16517 16525
8. P.F. Almeida Membrane-active peptides: binding, translocation, and flux in lipid vesicles. 1838 2014 2216 2227
9. H. Steiner, D. Hultmark, A. Engström, H. Bennich, and H.G. Boman Sequence and specificity of two antibacterial proteins involved in insect immunity Nature 292 1981 246 248 (Pubitemid 11001840)
10. T. Higashijima, K. Wakamatsu, M. Takemitsu, M. Fujino, T. Nakajima, and T. Miyazawa Conformational change of mastoparan from wasp venom on binding with phospholipid membrane FEBS Lett. 152 1983 227 230 (Pubitemid 13129700)
11. A. Tossi, L. Sandri, and A. Giangaspero Amphipathic, alpha-helical antimicrobial peptides Biopolymers 55 2000 4 30
12. S. Danner, G. Pabst, K. Lohner, and A. Hickel Structure and thermotropic behavior of the Staphylococcus aureus lipid lysyl- dipalmitoylphosphatidylglycerol Biophys. J. 94 2008 2150 2159
13. A. Pokorny, E.M. Kilelee, D. Wu, and P.F. Almeida The activity of the amphipathic peptide delta-lysin correlates with phospholipid acyl chain structure and bilayer elastic properties Biophys. J. 95 2008 4748 4755
14. S.M. Gregory, A.C. Cavenaugh, V. Journigan, A. Pokorny, and P.F.F. Almeida A quantitative model for the all-or-none permeabilization of phospholipid vesicles by the antimicrobial peptide cecropin A Biophys. J. 94 2008 1667 1680
15. A. Michalak, E. Cox, S. Pagentine, P. Seaton, and A. Pokorny The synthesis of aminoacylated phosphatidylethanolamines, stable analogs of bacterial lipids 2014 (in preparation)
16. J.C. Dittmer, and R.L. Lester A simple, specific spray for the detection of phospholipids on thin layer chromatograms J. Lipid Res. 5 1964 126 127
17. E.K. Ryu, and M. MacCoss Modification of the Dittmer-Lester reagent for the detection of phospholipid derivatives on thin-layer chromatograms J. Lipid Res. 20 1979 561 563 (Pubitemid 9215384)
18. G.R. Bartlett Phosphorous assay in column chromatography J. Biol. Chem. 234 1959 466 468
19. A. Pokorny, T.H. Birkbeck, and P.F.F. Almeida Mechanism and kinetics of delta-lysin interaction with phospholipid vesicles Biochemistry 41 2002 11044 11056 (Pubitemid 35001219)
20. P.F. Almeida, and A. Pokorny Binding and permeabilization of model membranes by amphipathic peptides Methods Mol. Biol. 618 2010 155 169
21. E. Kilelee, A. Pokorny, M.R. Yeaman, and A.S. Bayer Lysyl- phosphatidylglycerol attenuates membrane perturbation rather than surface association of the cationic antimicrobial peptide 6W-RP-1 in a model membrane system: implicationsfor daptomycin resistance Antimicrob. Agents Chemother. 54 2010 4476 4479
22. W. Xia, and M.F. Thorpe Percolation properties of random ellipses Phys. Rev. A 38 1988 2650 2656
23. S.D. Shoemaker, and T.K. Vanderlick Intramembrane electrostatic interactions destabilize lipid vesicles Biophys. J. 83 2002 2007 2014
24. F.Y. Chen, M.T. Lee, and H.W. Huang Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation Biophys. J. 84 2003 3751 3758 (Pubitemid 36637870)
25. E. Evans, V. Heinrich, F. Ludwig, and W. Rawicz Dynamic tension spectroscopy and strength of biomembranes Biophys. J. 85 2003 2342 2350 (Pubitemid 37210784)