High-resolution structure of a retrovial capsid hexameric amino-terminal domain

Nature

Volumn 431, Issue 7007, 2004, Pages 481-485

  Mortuza, Gulnahar B ^a   Haire, Lesley F ^a   Stevens, Anthony ^a   Smerdon, Stephen J ^a   Stoye, Jonathan P ^a   Taylor, Ian A ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; LIFE CYCLE; MATRIX ALGEBRA; MONOMERS; PROTEINS; STRUCTURAL ANALYSIS; X RAYS;

AETIOLOGICAL AGENTS; MOLECULAR LEVEL; RETROVIRAL PARTICLES;

VIRUSES;

BIOLOGY;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; DNA SEQUENCE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; STRUCTURE ANALYSIS; VIRUS CAPSID; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; MURINE LEUKEMIA VIRUS; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; VIRUS ASSEMBLY; X RAY CRYSTALLOGRAPHY;

MURINAE; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

CAPSID PROTEIN;

AMINO ACID SEQUENCE; BINDING SITES; CAPSID; CAPSID PROTEINS; CRYSTALLOGRAPHY, X-RAY; LEUKEMIA VIRUS, MURINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; VIRUS ASSEMBLY;

EID: 4644301808     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02915     Document Type: Article

References (30)

1. Swanstrom, R. & Wills, J.W. in Synthesis, Assembly and Processing of Viral Proteins (eds Coffin, J. M., Hughes, S. H. & Varmus, H. E.) (Cold Spring Harbor Laboratory Press, New York, 1997).
2. Briggs, J. A., Wilk, T., Welker, R., Krausslich, H. G. & Fuller, S. D. Structural organization of authentic, mature HIV-1 virions and cores. EMBO J. 22, 1707-1715 (2003).
3. Nermut, M. V. & Hockley, D. J. Comparative morphology and structural classification of retroviruses. Curr. Top. Microbiol. Immunol. 214, 1-24 (1996).
4. Li, S., Hill, C. P., Sundquist, W. I. & Finch, J. T. Image reconstructions of helical assemblies of the HIV-1 CA protein. Nature 407, 409-413 (2000).
5. Ganser, B. K., Cheng, A., Sundquist, W. I. & Yeager, M. Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly. EMBO J. 22, 2886-2892 (2003).
6. Kingston, R. L. et al. Structure and self-association of the Rous sarcoma virus capsid protein. Struct. Fold. Des. 8, 617-628 (2000).
7. Cornilescu, C. C., Bouamr, F., Yao, X., Carter, C. & Tjandra, N. Structural analysis of the N-terminal domain of the human T-cell leukemia virus capsid protein. J. Mol. Biol. 306, 783-797 (2001).
8. Gamble, T. R. et al. Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid. Cell 87, 1285-1294 (1996).
9. Gitti, R. K. et al. Structure of the amino-terminal core domain of the HIV-1 capsid protein. Science 273, 231-235 (1996).
10. Jin, Z., Jin, L., Peterson, D. L. & Lawson, C. L. Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26. J. Mol. Biol. 286, 83-93 (1999).
11. Khorasanizadeh, S., Campos-Olivas, R. & Summers, M. F. Solution structure of the capsid protein from the human T-cell leukemia virus type-I. J. Mol. Biol. 291, 491-505 (1999).
12. Nandhagopal, N. et al. Dimeric Rous sarcoma virus capsid protein structure relevant to immature Gag assembly. J. Mol. Biol. 335, 275-282 (2004).
13. Tang, C., Ndassa, Y. & Summers, M. F. Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein. Nature Struct. Biol. 9, 537-543 (2002).
14. Gross, I., Hohenberg, H., Huckhagel, C. & Krausslich, H. G. N-Terminal extension of human immunodeficiency virus capsid protein converts the in vitro assembly phenotype from tubular to spherical particles. J. Virol. 72, 4798-4810 (1998).
15. von Schwedler, U. K. et al. Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly. EMBO J. 17, 1555-1568 (1998); corrigendum 19, 2391 (2000).
16. Briggs, J. A. et al. The stoichiometry of Gag protein in HIV-1. Nature Struct. Mol. Biol. 11, 672-675 (2004).
17. Lanman, J. et al. Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry. J. Mol. Biol. 325, 759-772 (2003).
18. Lanman, J. et al. Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange. Nature Struct. Mol. Biol. 11, 676-677 (2004).
19. von Schwedler, U. K., Stray, K. M., Garrus, J. E. & Sundquist, W. I. Functional surfaces of the human immunodeficiency virus type 1 capsid protein. J. Virol. 77, 5439-5450 (2003).
20. Forshey, B. M., von Schwedler, U., Sundquist, W. I. & Aiken, C. Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication. J. Virol. 76, 5667-5677 (2002).
21. Ganser-Pornillos, B. K., von Schwedler, U. K., Stray, K. M., Aiken, C. & Sundquist, W. I. Assembly properties of the human immunodeficiency virus type 1 CA protein. J. Virol. 78, 2545-2552 (2004).
22. Fassati, A. & Goff, S. P. Characterization of intracellular reverse transcription complexes of Moloney murine leukemia virus. J. Virol. 73, 8919-8925 (1999).
23. Fassati, A. & Goff, S. P. Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1. J. Virol. 75, 3626-3635 (2001).
24. Karageorgos, L., Li, P. & Burrell, C. Characterization of HIV replication complexes early after cell-to-cell infection. AIDS Res. Hum. Retroviruses 9, 817-823 (1993).
25. Best, S., Le Tissier, P., Towers, G. & Stoye, J. P. Positional cloning of the mouse retrovirus restriction gene Fv1. Nature 382, 826-829 (1996).
26. Boone, L. R. et al. Reversal of Fv-1 host range by in vitro restriction endonuclease fragment exchange between molecular clones of N-tropic and B-tropic murine leukemia virus genomes. J. Virol. 48, 110-119 (1983).
27. Stremlau, M. et al. The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys. Nature 427, 848-853 (2004).
28. Terwilliger, T. C. & Berendzen, J. Automated MAD and MIR structure solution. Acta Crystallogr. D 55, 849-861 (1999).
29. Cowtan, K. 'dm': an automated procedure for phase improvement by density modification. Joint CCP4 ESF-EACBM Newsl. Prot. Crystallogr. 31, 34-38 (1994).
30. Morris, R. J., Perrakis, A. & Lamzin, V. S. ARP/wARP and automatic interpretation of protein electron density maps. Methods Enzymol. 374, 229-244 (2003).