Role of prostaglandins in determining the increased cardiac sympathetic nerve activity in ovine sepsis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 307, Issue 1, 2014, Pages

  Booth, Lindsea C ^a   Ramchandra, Rohit ^a   Calzavacca, Paolo ^a   May, Clive N ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Baroreflex curve; Cardiac sympathetic nerve activity; Indomethacin; Renal sympathetic nerve activity; Sepsis; Sheep

Indexed keywords

INDOMETACIN; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC SYMPATHETIC NERVE ACTIVITY; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DRUG EFFECT; ESCHERICHIA COLI; HEART RATE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; REFLEX; RENAL SYMPATHETIC NERVE ACTIVITY; RENAL SYSTEM PARAMETERS; SEPSIS; TEMPERATURE;

BAROREFLEX CURVE; CARDIAC SYMPATHETIC NERVE ACTIVITY; INDOMETHACIN; PGE2; RENAL SYMPATHETIC NERVE ACTIVITY; SEPSIS; SHEEP;

ANIMALS; ARTERIAL PRESSURE; BAROREFLEX; CAROTID ARTERIES; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ESCHERICHIA COLI INFECTIONS; FEMALE; HEART; HEART RATE; INFUSIONS, INTRA-ARTERIAL; KIDNEY; SEPSIS; SHEEP; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM; TIME FACTORS;

EID: 84903650302     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00450.2013     Document Type: Article

References (35)

1. Ackland GL, Yao ST, Rudiger A, Dyson A, Stidwill R, Poputnikov D, Singer M, Gourine AV. Cardioprotection, attenuated systemic inflammation, and survival benefit of beta1-adrenoceptor blockade in severe sepsis in rats. Crit Care Med 38: 388-394, 2010.
2. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29: 1303-1310, 2001.
3. Ariumi H, Takano Y, Masumi A, Takahashi S, Hirabara Y, Honda K, Saito R, Kamiya HO. Roles of the central prostaglandin EP3 receptors in cardiovascular regulation in rats. Neurosci Lett 324: 61-64, 2002.
4. 2 in conscious ewes. Proc Soc Exp Biol Med 180: 353-358, 1985.
5. 2 in conscious sheep. Am J Physiol Regul Integr Comp Physiol 256: R685-R693, 1989.
6. Cheyuo C, Jacob A, Wang P. Ghrelin-mediated sympathoinhibition and suppression of inflammation in sepsis. Am J Physiol Endocrinol Metab 302: E265-E272, 2012.
7. Di Giantomasso D, May CN, Bellomo R. Vital organ blood flow during hyperdynamic sepsis. Chest 124: 1053-1059, 2003.
8. Feigen LP. Actions of prostaglandins in peripheral vascular beds. Fed Proc 40: 1987-1990, 1981.
9. Fitzpatrick TM, Johnson M, Kot PA, Ramwell PW, Rose JC. Vasoconstrictor response to arachidonic acid in the isolated hind limb of the dog. Br J Pharmacol 59: 269-273, 1977.
10. Flower RJ, Vane JR. Inhibition of prostaglandin biosynthesis. Biochem Pharmacol 23: 1439-1450, 1974.
11. Fox J. The R Commander: A Basic Statistics Graphical User Interface to R. J Stat Softw 14: 1-42, 2005.
12. Groves AC, Griffiths J, Leung F, Meek RN. Plasma catecholamines in patients with serious postoperative infection. Ann Surg 178: 102-107, 1973.
13. Hofer S, Steppan J, Wagner T, Funke B, Lichtenstern C, Martin E, Graf BM, Bierhaus A, Weigand MA. Central sympatholytics prolong survival in experimental sepsis. Crit Care 13: R11, 2009.
14. Ishikawa K, Calzavacca P, Bellomo R, Bailey M, May CN. Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis. Crit Care Med 40: 2368-2375, 2012.
15. Kannan H, Tanaka Y, Kunitake T, Ueta Y, Hayashida Y, Yamashita H. Activation of sympathetic outflow by recombinant human interleukin-1 in conscious rats. Am J Physiol Regul Integr Comp Physiol 270: R479-R485, 1996.
16. Krishnagopalan S, Kumar A, Parrillo JE. Myocardial dysfunction in the patient with sepsis. Curr Opin Crit Care 8: 376-388, 2002.
17. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 31: 1250-1256, 2003.
18. Mason RT, Coghlan JP, Denton DA, Graham WF, Humphery TJ, Scoggins BA, Whitworth JA. Prostaglandin synthesis inhibition with indomethacin in ACTH-induced hypertension. J Cardiovasc Pharmacol 6: 288-292, 1984.
19. Morelli A, Ertmer C, Westphal M, Rehberg S, Kampmeier T, Ligges S, Orecchioni A, D'Egidio A, D'Ippoliti F, Raffone C, Venditti M, Guarracino F, Girardis M, Tritapepe L, Pietropaoli P, Mebazaa A, Singer M. Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial. JAMA 310: 1683-1691, 2013.
20. Mori T, Shimizu T, Tani T. Septic acute renal failure. Contrib Nephrol 166: 40-46, 2010.
21. Neveu H, Kleinknecht D, Brivet F, Loirat P, Landais P. Prognostic factors in acute renal failure due to sepsis. Results of a prospective multicentre study: The French Study Group on Acute Renal Failure. Nephrol Dial Transplant 11: 293-299, 1996.
22. Palsson J, Ricksten SE, Delle M, Lundin S. Changes in renal sympathetic nerve activity during experimental septic and endotoxin shock in conscious rats. Circ Shock 24: 133-141, 1988.
23. Core Team R. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing, 2013.
24. Ramchandra R, Wan L, Hood SG, Frithiof R, Bellomo R, May CN. Septic shock induces distinct changes in sympathetic nerve activity to the heart and kidney in conscious sheep. Am J Physiol Regul Integr Comp Physiol 297: R1247-R1253, 2009.
25. Revhaug A, Michie HR, Manson JM, Watters JM, Dinarello CA, Wolff SM, Wilmore DW. Inhibition of cyclo-oxygenase attenuates the metabolic response to endotoxin in humans. Arch Surg 123: 162-170, 1988.
26. Riedel W, Kozawa E, Iriki M. Renal and cutaneous vasomotor and respiratory rate adjustments to peripheral cold and warm stimuli and to bacterial endotoxin in conscious rabbits. J Auton Nerv Syst 5: 177-194, 1982.
27. Sayk F, Vietheer A, Schaaf B, Wellhoener P, Weitz G, Lehnert H, Dodt C. Endotoxemia causes central downregulation of sympathetic vasomotor tone in healthy humans. Am J Physiol Regul Integr Comp Physiol 295: R891-R898, 2008.
28. Schoenberg MH, Weiss M, Radermacher P. Outcome of patients with sepsis and septic shock after ICU treatment. Langenbecks Arch Surg 383: 44-48, 1998.
29. Tang CH, Chan GS, Middleton PM, Cave G, Harvey M, Savkin AV, Lovell NH. Transfer function analysis of baroreflex function in a rabbit model of endotoxic shock. Conf Proc IEEE Eng Med Biol Soc 2009: 1848-1851, 2009.
30. Vayssettes-Courchay C, Bouysset F, Verbeuren TJ. Involvement of COX and NOS induction in the sympatho-activation during sepsis. Auton Neurosci 98: 33-36, 2002.
31. Wallis G, Brackett D, Lerner M, Kotake Y, Bolli R, McCay PB. In vivo spin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study. Shock 6: 274-278, 1996.
32. Watson A, Hood S, Ramchandra R, McAllen R, May C. Increased cardiac sympathetic nerve activity in heart failure is not due to desensitization of the arterial baroreflex. Am J Physiol Heart Circ Physiol 293: H798-H804, 2007.
33. Wilson J, Higgins D, Hutting H, Serkova N, Baird C, Khailova L, Queensland K, Weitzel L, Tran ZV, Wischmeyer PE. Early propranolol treatment induces lung heme-oxygenase-1, attenuates metabolic dysfunction, and improves survival following experimental sepsis. Crit Care 17: R195, 2013.
34. Zhang ZH, Wei SG, Francis J, Felder RB. Cardiovascular and renal sympathetic activation by blood-borne TNF-α in rat: the role of central prostaglandins. Am J Physiol Regul Integr Comp Physiol 284: R916-R927, 2003.
35. 2-induced hypothalamic paraventricular nucleus excitation and sympathetic activation. Am J Physiol Heart Circ Physiol 301: H1559-H1569, 2011.