Variation in motor output and motor performance in a centrally generated motor pattern

Journal of Neurophysiology

Volumn 112, Issue 1, 2014, Pages 95-109

  Wenning, Angela ^a   Norris, Brian J ^a,b   Doloc Mihu, Anca ^a   Calabrese, Ronald L ^a  

^a EMORY UNIVERSITY   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Intersegmental coordination; Leech; Motor pattern in vivo; Motor performance; Variability

Indexed keywords

ANIMAL BEHAVIOR; ARTICLE; BLADDER; CENTRAL PATTERN GENERATOR; CONTROLLED STUDY; ELECTROPHYSIOLOGICAL PROCEDURES; HEART BEAT; HEART MOVEMENT; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; IN VITRO STUDY; IN VIVO STUDY; LEECH; MOTONEURON; MOTOR OUTPUT; MOTOR PERFORMANCE; NONHUMAN; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; SENSORY FEEDBACK; SIGNAL NOISE RATIO; ANIMAL; HEART; HEART CONTRACTION; INNERVATION; PHYSIOLOGY;

ANIMALS; CENTRAL PATTERN GENERATORS; HEART; LEECHES; MOTOR NEURONS; MYOCARDIAL CONTRACTION;

EID: 84903589674     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00856.2013     Document Type: Article

References (42)

1. Arbas EA. Rate modification in the heartbeat central pattern generator of the medicinal leech. J Comp Physiol A 155: 783-794, 1984.
2. Arbas EA, Calabrese RL. Leydig neuron activity modulates heartbeat in the medicinal leech. J Comp Physiol A 167: 665-671, 1990.
3. Brezina V, Orekhova IV, Weiss KR. The neuromuscular transform: the dynamic, nonlinear link between motor neuron firing patterns and muscle contraction in rhythmic behaviors. J Neurophysiol 83: 207-231, 2000.
4. Calabrese RL. The neural control of alternate heartbeat coordination states in the leech, Hirudo medicinalis. J Comp Physiol A 122: 11-143, 1977.
5. Calabrese RL. The roles of endogenous membrane properties and synaptic interaction in generating the heartbeat rhythm of the leech, Hirudo medicinalis. J Exp Biol 82: 163-176, 1979.
6. Calabrese RL. The heartbeat neural control system of the leech. In: Handbook of Microcircuits, edited by Shepherd GM, Grillner S. Oxford, UK: Oxford Univ. Press, 2010, p. 450-456.
7. Calabrese RL, Maranto AR. Neural control of the hearts in the leech, Hirudo medicinalis. III. Regulation of myogenicity and muscle tension by heart accessory neurons. J Comp Physiol A 154: 393-406, 1984.
8. Calabrese RL, Norris BJ, Wenning A, Wright TM. Coping with variability in small neuronal networks. Integr Comp Biol 51: 845-855, 2011.
9. Callaway EM, Marder E. Common features of diverse circuits. Curr Opin Neurobiol 22: 565-567, 2012.
10. Cymbalyuk GS, Gaudry Q, Masino MA, Calabrese RL. Bursting in leech heart interneurons: cell-autonomous and network-based mechanisms. J Neurosci 22: 10580-10592, 2002.
11. Davis RL. Influence of oxygen on the heartbeat rhythm of the leech. J Exp Biol 123: 401-408, 1986.
12. Diehl F, White RS, Stein W, Nusbaum MP. Motor circuit-specific burst patterns drive different muscle and behavior patterns. J Neurosci 33: 12013-12029, 2013.
13. Friesen WO, Cang J. Sensory and central mechanisms control intersegmental coordination. Curr Opin Neurobiol 11: 678-683, 2001.
14. Garcia-Crescioni K, Fort TJ, Stern E, Brezina V, Miller MW. Feedback from peripheral musculature to central pattern generator in the neurogenic heart of the crab Callinectes sapidus: role of mechanosensitive dendrites. J Neurophysiol 103: 83-96, 2010.
15. Goaillard JM. Neural networks: more about flexibility than synaptic strength. Curr Biol 21: R276-R278, 2011.
16. Goeritz ML, Soofi W, Stein WA, Prinz AA, Marder E. Pyloric network responses to temperature changes in vivo (Abstract). Soc Neurosci Abstr 2013: 372.-09, 2013.
17. Golowasch J, Goldman MS, Abbott LF, Marder E. Failure of averaging in the construction of a conductance-based neuron model. J Neurophysiol 87: 1129-1131, 2002.
18. Hildebrandt JP. Circulation in the leech, Hirudo medicinalis L. J Exp Biol 134: 235-246, 1988.
19. Krahl B, Zerbst-Boroffka I. Blood pressure in the leech Hirudo medicinalis. J Exp Biol 107: 163-168, 1983.
20. Mahadevan A, Lappe J, Rhyne RT, Cruz-Bermudez ND, Marder E, Goy MF. Nitric oxide inhibits the rate and strength of cardiac contractions in the lobster Homarus americanus by acting on the cardiac ganglion. J Neurosci 24: 2813-2824, 2004.
21. Maranto AR, Calabrese RL. Neural control of the hearts in the leech, Hirudo medicinalis. I. Anatomy, electrical coupling, and innervation of the hearts. J Comp Physiol A 154: 367-380, 1984a.
22. Maranto AR, Calabrese RL. Neural control of the hearts in the leech, Hirudo medicinalis. II. Myogenic activity and its control by heart motor neurons. J Comp Physiol A 154: 381-391, 1984b.
23. Marder E, Calabrese RL. Principles of rhythmic motor pattern generation. Physiol Rev 76: 687-717, 1996.
24. Morton DW, Chiel HJ. In vivo buccal nerve activity that distinguishes ingestion from rejection can be used to predict behavioral transitions in Aplysia. J Comp Physiol A 172: 17-32, 1993a.
25. Morton DW, Chiel HJ. The timing of activity in motor neurons that produce radula movements distinguishes ingestion from rejection in Aplysia. J Comp Physiol A 173: 519-536, 1993b.
26. Norris BJ, Weaver AL, Morris LG, Wenning A, Garcìa PA, Calabrese RL. A central pattern generator producing alternative outputs: temporal pattern of premotor activity. J Neurophysiol 96: 309-326, 2006.
27. Norris BJ, Weaver AL, Wenning A, Garcìa PS, Calabrese RL. A central pattern generator producing alternative outputs: phase relations of leech heart motor neurons with respect to premotor synaptic input. J Neurophysiol 98: 2983-2991, 2007.
28. Norris BJ, Wenning A, Wright TM, Calabrese RL. Constancy and variability in the output of a central pattern generator. J Neurosci 31: 4663-4674, 2011.
29. Peterson EL, Calabrese RL. Dynamic analysis of a rhythmic neural circuit in the leech Hirudo medicinalis. J Neurophysiol 47: 256-271, 1982.
30. Pittendrigh CS (Editor). Circadian Oscillations in Cells and the Circadian Organization of Multicellular Systems. Cambridge, MA: MIT Press, 1974, p. 437-458.
31. Roffman RC, Norris BJ, Calabrese RL. Animal-to-animal variability of connection strength in the leech heartbeat central pattern generator. J Neurophysiol 107: 1681-1693, 2012.
32. Siddall ME, Trontelj P, Utevsky SY, Nkamany M, Macdonald KS. Diverse molecular data demonstrate that commercially available medicinal leeches are not Hirudo medicinalis. Proc Biol Sci 274: 1481-1487, 2007.
33. Tang LS, Goeritz ML, Caplan JS, Taylor AL, Fisek M, Marder E. Precise temperature compensation of phase in a rhythmic motor pattern. PLoS Biol 8: e1000469, 2010.
34. Thompson WJ, Stent GS. Neuronal control of heartbeat in the medicinal leech. II. Intersegmental coordination of heart motor neuron activity by heart interneurons. J Comp Physiol 111: 281-307, 1976.
35. Wenning A, Cymbalyuk GS, Calabrese RL. Heartbeat control in leeches. I. Constriction pattern and neural modulation of blood pressure in intact animals. J Neurophysiol 91: 382-396, 2004a.
36. Wenning A, Hill AA, Calabrese RL. Heartbeat control in leeches. II. Fictive motor pattern. J Neurophysiol 91: 397-409, 2004b.
37. Wenning A, Meyer EP. Hemodynamics in the leech: blood flow in two hearts switching between two constriction patterns. J Exp Biol 210: 2627-2636, 2007.
38. Wenning A, Norris BJ, Doloc-Mihu A, Calabrese RL. Bringing up the rear: new premotor interneurons add regional complexity to a segmentally distributed motor pattern. J Neurophysiol 106: 2201-2215, 2011.
39. Wenning A, Zerbst-Boroffka I, Bazin B. Water and salt excretion in Hirudo medicinalis. J Comp Physiol B 139: 97-102, 1980.
40. Williams AH, Calkins A, O'Leary T, Symonds R, Marder E, Dickinson PS. The neuromuscular transform of the lobster cardiac system explains the opposing effects of a neuromodulator on muscle output. J Neurosci 33: 16565-16575, 2013.
41. Wright TM Jr, Calabrese RL. Patterns of presynaptic activity and synaptic strength interact to produce motor output. J Neurosci 31: 17555-17571, 2011.
42. Zerbst-Boroffka I. Osmo-und Volumenregulation bei Hirudo medicinalis nach Nahrungsaufnahme. J Comp Physiol 84: 185-204, 1973.