메뉴 건너뛰기




Volumn 23, Issue 8, 2014, Pages 802-812

Immunomodulatory effects of H.P. Acthar gel on B cell development in the NZB/W F1 mouse model of systemic lupus erythematosus

Author keywords

ACTH; Acthar Gel; B cells; Melanocortin peptides; NZB W F1; Systemic lupus erythematosus

Indexed keywords

ACTHAR GEL H.P; CORTICOTROPIN; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; PLACEBO; PREDNISOLONE SODIUM SUCCINATE; UNCLASSIFIED DRUG; GEL; HORMONE;

EID: 84903549365     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203314531840     Document Type: Article
Times cited : (25)

References (51)
  • 2
    • 54149096930 scopus 로고    scopus 로고
    • Developments in the scientific understanding of lupus
    • Ardoin SP, Pisetsky DS. Developments in the scientific understanding of lupus. Arthritis Res Ther 2008; 10: 218.
    • (2008) Arthritis Res Ther , vol.10 , pp. 218
    • Ardoin, S.P.1    Pisetsky, D.S.2
  • 3
    • 32044454695 scopus 로고    scopus 로고
    • B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation
    • William J, Euler C, Primarolo N, et al. B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation. J Immunol 2006; 176: 2142-2151.
    • (2006) J Immunol , vol.176 , pp. 2142-2151
    • William, J.1    Euler, C.2    Primarolo, N.3
  • 4
    • 15444365480 scopus 로고    scopus 로고
    • Defective B cell tolerance checkpoints in systemic lupus erythematosus
    • Yurasov S, Wardemann H, Hammersen J, et al. Defective B cell tolerance checkpoints in systemic lupus erythematosus. J Exper Med 2005; 201: 703-711.
    • (2005) J Exper Med , vol.201 , pp. 703-711
    • Yurasov, S.1    Wardemann, H.2    Hammersen, J.3
  • 5
    • 38449101693 scopus 로고    scopus 로고
    • B cell biology and dysfunction in SLE
    • Anolik JH. B cell biology and dysfunction in SLE. Bull NYU Hosp Jt Dis 2007; 65: 182-186.
    • (2007) Bull NYU Hosp Jt Dis , vol.65 , pp. 182-186
    • Anolik, J.H.1
  • 6
    • 84868359403 scopus 로고    scopus 로고
    • Treatment targets in systemic lupus erythematosus: Biology and clinical perspective
    • Marian V, Anolik JH. Treatment targets in systemic lupus erythematosus: Biology and clinical perspective. Arthritis Res Ther 2012; 14(Suppl. 4): S3.
    • (2012) Arthritis Res Ther , vol.14 , Issue.SUPPL. 4
    • Marian, V.1    Anolik, J.H.2
  • 7
    • 77951739752 scopus 로고    scopus 로고
    • Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice
    • Ramanujam M, Bethunaickan R, Huang W, et al. Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice. Arthritis Rheum 2010; 62: 1457-1468.
    • (2010) Arthritis Rheum , vol.62 , pp. 1457-1468
    • Ramanujam, M.1    Bethunaickan, R.2    Huang, W.3
  • 8
    • 1842339305 scopus 로고    scopus 로고
    • The melanocortin 1,3 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH
    • Schioth HB, Muceniece R, Larsson M, et al. The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH. J Endocrinol 1997; 155: 73-78.
    • (1997) J Endocrinol , vol.155 , pp. 73-78
    • Schioth, H.B.1    Muceniece, R.2    Larsson, M.3
  • 9
    • 1542347163 scopus 로고    scopus 로고
    • Targeting melanocortin receptors as a novel strategy to control inflammation
    • Catania A, Gatti S, Colombo G, et al. Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol Rev 2004; 56: 1-29.
    • (2004) Pharmacol Rev , vol.56 , pp. 1-29
    • Catania, A.1    Gatti, S.2    Colombo, G.3
  • 10
    • 78349285554 scopus 로고    scopus 로고
    • The melanocortin system in control of inflammation
    • Catania A, Lonati C, Sordi A, et al. The melanocortin system in control of inflammation. ScientificWorldJournal 2010; 10: 1840-1853.
    • (2010) Scientific World Journal , vol.10 , pp. 1840-1853
    • Catania, A.1    Lonati, C.2    Sordi, A.3
  • 11
    • 84858601260 scopus 로고    scopus 로고
    • Treatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH)
    • Bomback AS, Radhakrishnan J. Treatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH). Discov Med 2011; 12: 91-96.
    • (2011) Discov Med , vol.12 , pp. 91-96
    • Bomback, A.S.1    Radhakrishnan, J.2
  • 12
    • 24744466460 scopus 로고    scopus 로고
    • Effect of alpha-melanocytestimulating hormone on interleukin 8 and monocyte chemotactic protein 1 expression in a human retinal pigment epithelial cell line
    • Cui HS, Hayasaka S, Zhang XY, et al. Effect of alpha- melanocytestimulating hormone on interleukin 8 and monocyte chemotactic protein 1 expression in a human retinal pigment epithelial cell line. Ophthalmic Res 2005; 37: 279-288.
    • (2005) Ophthalmic Res , vol.37 , pp. 279-288
    • Cui, H.S.1    Hayasaka, S.2    Zhang, X.Y.3
  • 13
    • 79952245992 scopus 로고    scopus 로고
    • Ingested (oral) ACTH inhibits EAE
    • Brod SA, Hood ZM. Ingested (oral) ACTH inhibits EAE. J Neuroimmunol 2011; 232: 131-135.
    • (2011) J Neuroimmunol , vol.232 , pp. 131-135
    • Brod, S.A.1    Hood, Z.M.2
  • 14
    • 0030978140 scopus 로고    scopus 로고
    • Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats
    • Chiao H, Kohda Y, McLeroy P, et al. Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats. J Clin Invest 1997; 99: 1165-1172.
    • (1997) J Clin Invest , vol.99 , pp. 1165-1172
    • Chiao, H.1    Kohda, Y.2    McLeroy, P.3
  • 15
    • 11144266618 scopus 로고    scopus 로고
    • The effect of alpha-melanocytestimulating hormone on renal tubular cell apoptosis and tubulointerstitial fibrosis in cyclosporine A nephrotoxicity
    • Lee SY, Jo SK, Cho WY, et al. The effect of alpha-melanocytestimulating hormone on renal tubular cell apoptosis and tubulointerstitial fibrosis in cyclosporine A nephrotoxicity. Transplantation 2004; 78: 1756-1764.
    • (2004) Transplantation , vol.78 , pp. 1756-1764
    • Lee, S.Y.1    Jo, S.K.2    Cho, W.Y.3
  • 16
    • 84875697942 scopus 로고    scopus 로고
    • Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms
    • Si J, Ge Y, Zhuang S, et al. Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms. Kidney Int 2013; 83: 635-646.
    • (2013) Kidney Int , vol.83 , pp. 635-646
    • Si, J.1    Ge, Y.2    Zhuang, S.3
  • 17
    • 77955609123 scopus 로고    scopus 로고
    • Melanocortin 1 receptor agonists reduce proteinuria
    • Lindskog A, Ebefors K, Johansson ME, et al. Melanocortin 1 receptor agonists reduce proteinuria. J Am Soc Nephrol 2010; 21: 1290-1298.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1290-1298
    • Lindskog, A.1    Ebefors, K.2    Johansson, M.E.3
  • 18
    • 84862496379 scopus 로고    scopus 로고
    • Treatment of resistant glomerular diseases with adrenocorticotropic hormone gel: A prospective trial
    • Bomback AS, Canetta PA, Beck Jr LH, et al. Treatment of resistant glomerular diseases with adrenocorticotropic hormone gel: A prospective trial. Am J Nephrol 2012; 36: 58-67.
    • (2012) Am J Nephrol , vol.36 , pp. 58-67
    • Bomback, A.S.1    Canetta, P.A.2    Beck Jr., L.H.3
  • 19
    • 84903526322 scopus 로고
    • The natural history of lupus erythematosus and its modification by cortisone and corticotrophin (A.C.T.H.)
    • Cohen H, Cadman EF. The natural history of lupus erythematosus and its modification by cortisone and corticotrophin (A.C.T.H.). Lancet 1953; 265: 306-312.
    • (1953) Lancet , vol.265 , pp. 306-312
    • Cohen, H.1    Cadman, E.F.2
  • 20
    • 84873765173 scopus 로고
    • The effect of adrenocorticotropic hormone (ACTH) and cortisone on the course of disseminated lupus erythematosus and peri-arteritis nodosa. Bull
    • Johns Hopkins
    • Carey RA, Harvey AM, Howard JE. The effect of adrenocorticotropic hormone (ACTH) and cortisone on the course of disseminated lupus erythematosus and peri-arteritis nodosa. Bull Johns Hopkins Hosp 1950; 87: 425-460.
    • (1950) Hosp , vol.87 , pp. 425-460
    • Carey, R.A.1    Harvey, A.M.2    Howard, J.E.3
  • 21
    • 38349073476 scopus 로고    scopus 로고
    • Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies
    • Takahashi T, Strober S. Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies. Eur J Immunol 2008; 38: 156-165.
    • (2008) Eur J Immunol , vol.38 , pp. 156-165
    • Takahashi, T.1    Strober, S.2
  • 22
    • 84863622596 scopus 로고    scopus 로고
    • B cell tolerance and positive selection in lupus
    • Eilat D, Wabl M. B cell tolerance and positive selection in lupus. J Immunol 2012; 189: 503-509.
    • (2012) J Immunol , vol.189 , pp. 503-509
    • Eilat, D.1    Wabl, M.2
  • 23
    • 79953283896 scopus 로고    scopus 로고
    • Murine models of systemic lupus erythematosus
    • Perry D, Sang A, Yin Y, et al. Murine models of systemic lupus erythematosus. J Biomed Biotechnol 2011; 2716942011.
    • (2011) J Biomed Biotechnol , pp. 2716942011
    • Perry, D.1    Sang, A.2    Yin, Y.3
  • 24
    • 0014259755 scopus 로고
    • Pathogenesis of the glomerulonephritis of NZB/W mice
    • Lambert PH, Dixon FJ. Pathogenesis of the glomerulonephritis of NZB/W mice. J Exper Med 1968; 127: 507-522.
    • (1968) J Exper Med , vol.127 , pp. 507-522
    • Lambert, P.H.1    Dixon, F.J.2
  • 25
    • 0016477799 scopus 로고
    • Influence of cyclophosphamide and other immunosuppressive drugs on immune disorders and neoplasia in NZB/NZW mice
    • Hahn BH, Knotts L, Ng M, et al. Influence of cyclophosphamide and other immunosuppressive drugs on immune disorders and neoplasia in NZB/NZW mice. Arthritis Rheum 1975; 18: 145-152.
    • (1975) Arthritis Rheum , vol.18 , pp. 145-152
    • Hahn, B.H.1    Knotts, L.2    Ng, M.3
  • 26
    • 23744432462 scopus 로고    scopus 로고
    • Balancing diversity and tolerance: Lessons from patients with systemic lupus erythematosus
    • Jacobi AM, Diamond B. Balancing diversity and tolerance: Lessons from patients with systemic lupus erythematosus. J Exper Med 2005; 202: 341-344.
    • (2005) J Exper Med , vol.202 , pp. 341-344
    • Jacobi, A.M.1    Diamond, B.2
  • 27
    • 84873627152 scopus 로고    scopus 로고
    • Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis
    • Arnason BG, Berkovich R, Catania A, et al. Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis. Mult Scler 2013; 19: 130-136.
    • (2013) Mult Scler , vol.19 , pp. 130-136
    • Arnason, B.G.1    Berkovich, R.2    Catania, A.3
  • 28
    • 0036912422 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha stimulated NFkappaB/p65 in human keratinocytes by alpha-melanocyte stimulating hormone and adrenocorticotropic hormone peptides
    • Moustafa M, Szabo M, Ghanem GE, et al. Inhibition of tumor necrosis factor-alpha stimulated NFkappaB/p65 in human keratinocytes by alpha-melanocyte stimulating hormone and adrenocorticotropic hormone peptides. J Invest Dermatol 2002; 119: 1244-1253.
    • (2002) J Invest Dermatol , vol.119 , pp. 1244-1253
    • Moustafa, M.1    Szabo, M.2    Ghanem, G.E.3
  • 29
    • 4344597627 scopus 로고    scopus 로고
    • Mechanism of action of transmembrane activator and calcium modulator ligand interactor- Ig in murine systemic lupus erythematosus
    • Ramanujam M, Wang X, Huang W, et al. Mechanism of action of transmembrane activator and calcium modulator ligand interactor- Ig in murine systemic lupus erythematosus. J Immunol 2004; 173: 3524-3534.
    • (2004) J Immunol , vol.173 , pp. 3524-3534
    • Ramanujam, M.1    Wang, X.2    Huang, W.3
  • 30
    • 33644660402 scopus 로고    scopus 로고
    • Similarities and differences between selective and nonselective BAFF blockade in murine SLE
    • Ramanujam M, Wang X, Huang W, et al. Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest 2006; 116: 724-734.
    • (2006) J Clin Invest , vol.116 , pp. 724-734
    • Ramanujam, M.1    Wang, X.2    Huang, W.3
  • 31
    • 70350515662 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision
    • Pillai S, Cariappa A. The follicular versus marginal zone B lymphocyte cell fate decision. Nat Rev Immunol 2009; 9: 767-777.
    • (2009) Nat Rev Immunol , vol.9 , pp. 767-777
    • Pillai, S.1    Cariappa, A.2
  • 32
    • 70349336151 scopus 로고    scopus 로고
    • B cell receptor and BAFF receptor signaling regulation of B cell homeostasis
    • Khan WN. B cell receptor and BAFF receptor signaling regulation of B cell homeostasis. J Immunol 2009; 183: 3561-3567.
    • (2009) J Immunol , vol.183 , pp. 3561-3567
    • Khan, W.N.1
  • 33
    • 79959969421 scopus 로고    scopus 로고
    • Regulation of B cell activating factor (BAFF) receptor expression by NF-KappaB signaling in rheumatoid arthritis B cells
    • Woo YJ, Yoon BY, Jhun JY, et al. Regulation of B cell activating factor (BAFF) receptor expression by NF-KappaB signaling in rheumatoid arthritis B cells. Exp Mol Med 2011; 43: 350-357.
    • (2011) Exp Mol Med , vol.43 , pp. 350-357
    • Woo, Y.J.1    Yoon, B.Y.2    Jhun, J.Y.3
  • 34
    • 53149103899 scopus 로고    scopus 로고
    • Therapeutic downregulation of central and peripheral B-cell-activating factor (BAFF) production in pediatric opsoclonus-myoclonus syndrome
    • Pranzatelli MR, Tate ED, Hoefgen ER, et al. Therapeutic downregulation of central and peripheral B-cell-activating factor (BAFF) production in pediatric opsoclonus-myoclonus syndrome. Cytokine 2008; 44: 26-32.
    • (2008) Cytokine , vol.44 , pp. 26-32
    • Pranzatelli, M.R.1    Tate, E.D.2    Hoefgen, E.R.3
  • 35
    • 72449136292 scopus 로고    scopus 로고
    • Insights into the heterogeneity of human B cells: Diverse functions, roles in autoimmunity, and use as therapeutic targets
    • Anolik JH, Looney RJ, Lund FE, et al. Insights into the heterogeneity of human B cells: Diverse functions, roles in autoimmunity, and use as therapeutic targets. Immunol Res 2009; 45: 144-158.
    • (2009) Immunol Res , vol.45 , pp. 144-158
    • Anolik, J.H.1    Looney, R.J.2    Lund, F.E.3
  • 38
    • 33845805695 scopus 로고    scopus 로고
    • Lupus resistance is associated with marginal zone abnormalities in an NZM murine model
    • Duan B, Croker BP, Morel L. Lupus resistance is associated with marginal zone abnormalities in an NZM murine model. Lab Invest 2007; 87: 14-28.
    • (2007) Lab Invest , vol.87 , pp. 14-28
    • Duan, B.1    Croker, B.P.2    Morel, L.3
  • 39
    • 36849090653 scopus 로고    scopus 로고
    • Depletion of B cells in murine lupus: Efficacy and resistance
    • Ahuja A, Shupe J, Dunn R, et al. Depletion of B cells in murine lupus: Efficacy and resistance. J Immunol 2007; 179: 3351-3361.
    • (2007) J Immunol , vol.179 , pp. 3351-3361
    • Ahuja, A.1    Shupe, J.2    Dunn, R.3
  • 40
    • 19944427673 scopus 로고    scopus 로고
    • Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy
    • Gong Q, Ou Q, Ye S, et al. Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J Immunol 2005; 174: 817-826.
    • (2005) J Immunol , vol.174 , pp. 817-826
    • Gong, Q.1    Ou, Q.2    Ye, S.3
  • 41
    • 77955406522 scopus 로고    scopus 로고
    • Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus
    • Bekar KW, Owen T, Dunn R, et al. Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus. Arthritis Rheum 2010; 62: 2443-2457.
    • (2010) Arthritis Rheum , vol.62 , pp. 2443-2457
    • Bekar, K.W.1    Owen, T.2    Dunn, R.3
  • 43
    • 0001726802 scopus 로고
    • Regulation of the in vitro antibody response by neuroendocrine hormones
    • Johnson HM, Smith EM, Torres BA, et al. Regulation of the in vitro antibody response by neuroendocrine hormones. Proc Natl Acad Sci U S A 1982; 79: 4171-4174.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 4171-4174
    • Johnson, H.M.1    Smith, E.M.2    Torres, B.A.3
  • 44
    • 0024365082 scopus 로고
    • Differential expression of functional adrenocorticotropic hormone receptors by subpopulations of lymphocytes
    • Clarke BL, Bost KL. Differential expression of functional adrenocorticotropic hormone receptors by subpopulations of lymphocytes. J Immunol 1989; 143: 464-469.
    • (1989) J Immunol , vol.143 , pp. 464-469
    • Clarke, B.L.1    Bost, K.L.2
  • 45
    • 84859921644 scopus 로고    scopus 로고
    • Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice
    • Stirzaker RA, Biswas PS, Gupta S, et al. Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice. Lupus 2012; 21: 656-661.
    • (2012) Lupus , vol.21 , pp. 656-661
    • Stirzaker, R.A.1    Biswas, P.S.2    Gupta, S.3
  • 46
    • 0037868032 scopus 로고    scopus 로고
    • Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition
    • Schiffer L, Sinha J, Wang X, et al. Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition. J Immunol 2003; 171: 489-497.
    • (2003) J Immunol , vol.171 , pp. 489-497
    • Schiffer, L.1    Sinha, J.2    Wang, X.3
  • 47
    • 66449123868 scopus 로고    scopus 로고
    • Decrease in glomerulonephritis and Th1-associated autoantibody production after progesterone treatment in NZB/NZW mice
    • Hughes GC, Martin D, Zhang K, et al. Decrease in glomerulonephritis and Th1-associated autoantibody production after progesterone treatment in NZB/NZW mice. Arthritis Rheum 2009; 60: 1775-1784.
    • (2009) Arthritis Rheum , vol.60 , pp. 1775-1784
    • Hughes, G.C.1    Martin, D.2    Zhang, K.3
  • 48
    • 0023278475 scopus 로고
    • Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4
    • Wofsy D, Seaman WE. Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4. J Immunol 1987; 138: 3247-3253.
    • (1987) J Immunol , vol.138 , pp. 3247-3253
    • Wofsy, D.1    Seaman, W.E.2
  • 49
    • 40749132629 scopus 로고    scopus 로고
    • Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis
    • Schiffer L, Bethunaickan R, Ramanujam M, et al. Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis. J Immunol 2008; 180: 1938-1947.
    • (2008) J Immunol , vol.180 , pp. 1938-1947
    • Schiffer, L.1    Bethunaickan, R.2    Ramanujam, M.3
  • 50
    • 79955018853 scopus 로고    scopus 로고
    • A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis
    • Bethunaickan R, Berthier CC, Ramanujam M, et al. A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis. J Immunol 2011; 186: 4994-5003.
    • (2011) J Immunol , vol.186 , pp. 4994-5003
    • Bethunaickan, R.1    Berthier, C.C.2    Ramanujam, M.3
  • 51
    • 84864804112 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis and osteonecrosis
    • Weinstein RS. Glucocorticoid-induced osteoporosis and osteonecrosis. Endocrinol Metab Clin North Am 2012; 41: 595-611.
    • (2012) Endocrinol Metab Clin North Am , vol.41 , pp. 595-611
    • Weinstein, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.