The protective role of interleukin-11 against neutron radiation injury in mouse intestines via MEK/ERK and PI3K/Akt dependent pathways

Digestive Diseases and Sciences

Volumn 59, Issue 7, 2014, Pages 1406-1414

  Yang, Leilei ^a   Wang, Ruijuan ^b   Gao, Yabing ^a   Xu, Xinping ^a   Fu, Kaifei ^a   Wang, Shaoxia ^a   Li, Yang ^a   Peng, Ruiyun ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b Beijing Military Region General Hospital   (China)

Author keywords

Intestinal epithelia; MEK ERK; Neutron irradiation; PI3K Akt

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RECOMBINANT INTERLEUKIN 11;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; CELL JUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DIARRHEA; FLOW CYTOMETRY; GOBLET CELL; IN VITRO STUDY; INTESTINE INJURY; MALE; MOUSE; NEUTRON RADIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIATION INJURY; RADIATION PROTECTION; SIGNAL TRANSDUCTION; SURVIVAL TIME;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-11; INTESTINE, SMALL; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; NEUTRONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 84903545894     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-013-3015-0     Document Type: Article

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