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Volumn 12, Issue 6, 2014, Pages 3323-3351

Metabolomic profiling and genomic study of a marine sponge-associated Streptomyces sp

Author keywords

Antifungal; Antimycin; Butenolide; Haliclona simulans; Metabolomics; Streptomyces

Indexed keywords

4 HYDROXY 10 METHYL 11 OXO DODEC 2 EN 1,4 OLIDE; 4,10 DIHYDROXY 10 METHYL DODEC 2 EN 1,4 OLIDE; 4,11 DIHYDROXY 10 METHYL DODEC 2 EN 1,4 OLIDE; ACTINOMYCIN X2; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIMYCIN A1; ANTIMYCIN A11; ANTIMYCIN A17; ANTIMYCIN A2; ANTIMYCIN A3; ANTIMYCIN A5; ANTIMYCIN A7; ANTIMYCIN A8; BUTENOLIDE; CANDICIDIN; CITRININ; DACTINOMYCIN; DEACETYL GLYKENIN A; DEACETYL GLYKENIN B; DEACETYL GLYKENIN C; GUANIDYLFUNGIN A; GUANIDYLFUNGIN B; KITASAMYCIN; KITASAMYCIN A; KITASAMYCIN B; NATURAL PRODUCT; SALINILACTAM; SATURATED FATTY ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84903521487     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12063323     Document Type: Article
Times cited : (47)

References (68)
  • 3
    • 34250733462 scopus 로고    scopus 로고
    • Sponge-associated microorganisms: Evolution, ecology, and biotechnological potential
    • DOI 10.1128/MMBR.00040-06
    • Taylor, M.; Radax, R.; Steger, D.; Wagner, M. Sponge-associated microorganisms: Evolution, ecology, and biotechnological potential. Microbiol. Mol. Biol. Rev. 2007, 71, 295-347. (Pubitemid 46954308)
    • (2007) Microbiology and Molecular Biology Reviews , vol.71 , Issue.2 , pp. 295-347
    • Taylor, M.W.1    Radax, R.2    Steger, D.3    Wagner, M.4
  • 5
    • 0024192007 scopus 로고
    • A marine micrococcus produces metabolites ascribed to the sponge Tedania ignis
    • Stierle, A.; Cardellina, J.; Singleton, F. A marine micrococcus produces metabolites ascribed to the sponge Tedania ignis. Experientia 1988, 44, 1021.
    • (1988) Experientia , vol.44 , pp. 1021
    • Stierle, A.1    Cardellina, J.2    Singleton, F.3
  • 6
    • 0001212607 scopus 로고
    • Discodermide-A new bioactive macrocyclic lactam from the marine sponge Discodermia dissoluta
    • Gunasekera, S.; Gunasekera, M.; McCarthy, P. Discodermide-A new bioactive macrocyclic lactam from the marine sponge Discodermia dissoluta. J. Org. Chem. 1991, 56, 4830-4833.
    • (1991) J. Org. Chem. , vol.56 , pp. 4830-4833
    • Gunasekera, S.1    Gunasekera, M.2    McCarthy, P.3
  • 7
    • 0017710502 scopus 로고
    • The structure of ikarugamycin, an acyltetramic acid antibiotic possessing a unique as-hydrindacene skeleton
    • DOI 10.1246/bcsj.50.1813
    • Ito, S.; Hirata, Y. The structure of ikarugamycin, an acyltetramic acid antibiotic possessing a unique asymmetric-hydrindacene skeleton. Bull. Chem. Soc. Jpn. 1977, 50, 1813-1820. (Pubitemid 8191278)
    • (1977) Bulletin of the Chemical Society of Japan , vol.50 , Issue.7 , pp. 1813-1820
    • Ito, S.1    Hirata, Y.2
  • 8
    • 63449122196 scopus 로고    scopus 로고
    • Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from irish waters
    • Kennedy, J.; Baker, P.; Piper, C.; Cotter, P.; Walsh, M.; Mooij, M.; Bourke, M.; Rea, M.; O'Connor, P.; Ross, R.; et al. Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from irish waters. Mar. Biotechnol. 2009, 11, 384-396.
    • (2009) Mar. Biotechnol. , vol.11 , pp. 384-396
    • Kennedy, J.1    Baker, P.2    Piper, C.3    Cotter, P.4    Walsh, M.5    Mooij, M.6    Bourke, M.7    Rea, M.8    O'Connor, P.9    Ross, R.10
  • 9
    • 78650066974 scopus 로고    scopus 로고
    • Streptomyces tateyamensis sp. nov., Streptomyces marinus sp. nov. and Streptomyces haliclonae s. nov., isolated from the marine sponge Haliclona sp
    • Khan, S.; Tamura, T.; Takagi, M.; Shin-ya, K. Streptomyces tateyamensis sp. nov., Streptomyces marinus sp. nov. and Streptomyces haliclonae s. nov., isolated from the marine sponge Haliclona sp. Int. J. Syst. Evol. Microbiol. 2010, 60, 2775-2779.
    • (2010) Int. J. Syst. Evol. Microbiol. , vol.60 , pp. 2775-2779
    • Khan, S.1    Tamura, T.2    Takagi, M.3    Shin-ya, K.4
  • 10
    • 79551487445 scopus 로고    scopus 로고
    • Streptomyces associated with a marine sponge Haliclona sp.; biosynthetic genes for secondary metabolites and products
    • Khan, S.; Komaki, H.; Motohashi, K.; Kozone, I.; Mukai, A.; Takagi, M.; Shin-ya, K. Streptomyces associated with a marine sponge Haliclona sp.; biosynthetic genes for secondary metabolites and products. Environ. Microbiol. 2011, 13, 391-403.
    • (2011) Environ. Microbiol. , vol.13 , pp. 391-403
    • Khan, S.1    Komaki, H.2    Motohashi, K.3    Kozone, I.4    Mukai, A.5    Takagi, M.6    Shin-ya, K.7
  • 12
    • 0029769378 scopus 로고    scopus 로고
    • Synergistic effects of a cellulase-producing Micromonospora carbonacea and an antibiotic-producing Streptomyces violascens on the suppression of Phytophthora cinnamomi root rot of Banksia grandis
    • El-Tarabily, K.A.; Sykes, M.L.; Kurtböke, I.D.; Hardy, G.E.S.J.; Barbosa, A.M.; Dekker, R.F.H. Synergistic effects of a cellulase-producing Micromonospora carbonacea and an antibiotic-producing Streptomyces violascens on the suppression of Phytophthora cinnamomi root rot of Banksia grandis. Can. J. Bot. 1996, 74, 618-624.
    • (1996) Can. J. Bot. , vol.74 , pp. 618-624
    • El-Tarabily, K.A.1    Sykes, M.L.2    Kurtböke, I.D.3    Hardy, G.E.S.J.4    Barbosa, A.M.5    Dekker, R.F.H.6
  • 13
    • 0015254698 scopus 로고
    • Protease inhibitors from Streptomyces violascens. 2. Production of the inhibitors
    • Jonsson, A.; Torstensson, N. Protease inhibitors from Streptomyces violascens. 2. Production of the inhibitors. Arch. Mikrobiol. 1972, 83, 71-77.
    • (1972) Arch. Mikrobiol. , vol.83 , pp. 71-77
    • Jonsson, A.1    Torstensson, N.2
  • 14
    • 0017125137 scopus 로고
    • Some enzymatic properties of 3beta-hydroxysteroid oxidase produced by Streptomyces violascens
    • Tomioka, H.; Kagawa, M.; Nakamura, S. Some enzymatic properties of 3beta-hydroxysteroid oxidase produced by Streptomyces violascens. J. Biochem. 1976, 79, 903-915.
    • (1976) J. Biochem. , vol.79 , pp. 903-915
    • Tomioka, H.1    Kagawa, M.2    Nakamura, S.3
  • 15
    • 33846000626 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolomics
    • DOI 10.1002/mas.20108
    • Dettmer, K.; Aronov, P.A.; Hammock, B.D. Mass spectrometry-based metabolomics. Mass Spectrom. Rev. 2007, 26, 51-78. (Pubitemid 46051813)
    • (2007) Mass Spectrometry Reviews , vol.26 , Issue.1 , pp. 51-78
    • Dettmer, K.1    Aronov, P.A.2    Hammock, B.D.3
  • 16
    • 30544454201 scopus 로고    scopus 로고
    • Metabolomics reviewed: A new "omics" platform technology for systems biology and implications for natural products research
    • DOI 10.1021/np050255w
    • Rochfort, S. Metabolomics reviewed: A new "Omics" Platform technology for systems biology and implications for natural products research. J. Nat. Prod. 2005, 68, 1813-1820. (Pubitemid 43082664)
    • (2005) Journal of Natural Products , vol.68 , Issue.12 , pp. 1813-1820
    • Rochfort, S.1
  • 17
    • 84867644221 scopus 로고    scopus 로고
    • Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach
    • Seipke, R.F.; Grüschow, S.; Goss, R.J.; Hutchings, M.I. Isolating antifungals from fungus-growing ant symbionts using a genome-guided chemistry approach. Methods Enzymol. 2012, 517, 47-70.
    • (2012) Methods Enzymol. , vol.517 , pp. 47-70
    • Seipke, R.F.1    Grüschow, S.2    Goss, R.J.3    Hutchings, M.I.4
  • 18
    • 79961040245 scopus 로고    scopus 로고
    • A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus
    • Seipke, R.F.; Barke, J.; Brearley, C.; Hill, L.; Yu, D.W.; Goss, R.J.; Hutchings, M.I. A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus . PLoS One 2011, 6, e22028.
    • (2011) PLoS One , vol.6
    • Seipke, R.F.1    Barke, J.2    Brearley, C.3    Hill, L.4    Yu, D.W.5    Goss, R.J.6    Hutchings, M.I.7
  • 20
    • 84934441555 scopus 로고    scopus 로고
    • Metabolomics and dereplication strategies in natural products
    • Tawfike, A.F.; Viegelmann, C.; Edrada-Ebel, R. Metabolomics and dereplication strategies in natural products. Methods Mol. Biol. 2013, 1055, 227-244.
    • (2013) Methods Mol. Biol. , vol.1055 , pp. 227-244
    • Tawfike, A.F.1    Viegelmann, C.2    Edrada-Ebel, R.3
  • 21
    • 84897048924 scopus 로고    scopus 로고
    • Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins a and b from a marine sponge associated-actinokineospora sp
    • Abdelmohsen, U.R.; Cheng, C.; Viegelmann, C.; Zhang, T.; Grkovic, T.; Ahmed, S.; Quinn, R.J.; Hentschel, U.; Edrada-Ebel, R. Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins a and b from a marine sponge associated-actinokineospora sp. Mar. Drugs 2014, 12, 1220-1244.
    • (2014) Mar. Drugs , vol.12 , pp. 1220-1244
    • Abdelmohsen, U.R.1    Cheng, C.2    Viegelmann, C.3    Zhang, T.4    Grkovic, T.5    Ahmed, S.6    Quinn, R.J.7    Hentschel, U.8    Edrada-Ebel, R.9
  • 28
    • 0021182730 scopus 로고
    • Studies on new antifungal antibiotics, guanidylfungins A and B. I. Taxonomy, fermentation, isolation and characterization
    • Takesako, K.; Beppu, T. Studies on new antifungal antibiotics, guanidylfungins a and b. I. Taxonomy, fermentation, isolation and characterization. J. Antibiot. 1984, 37, 1161-1169. (Pubitemid 14015827)
    • (1984) Journal of Antibiotics , vol.37 , Issue.10 , pp. 1161-1169
    • Takesako, K.1    Beppu, T.2
  • 29
    • 0021752669 scopus 로고
    • Studies on new antifungal antibiotics, guanidylfungins A and B. II. Structure elucidation and biosynthesis
    • Takesako, K.; Beppu, T. Studies on new antifungal antibiotics, guanidylfungins a and b. II. Structure elucidation and biosynthesis. J. Antibiot. 1984, 37, 1170-1186. (Pubitemid 15204438)
    • (1984) Journal of Antibiotics , vol.37 , Issue.10 , pp. 1170-1186
    • Takesako, K.1    Beppu, T.2
  • 31
    • 0347038783 scopus 로고
    • The chemistry of antimycin a. 6. Separation and properties of antimycin a subcomponents
    • Liu, W.; Strong, F. The chemistry of antimycin a. 6. Separation and properties of antimycin a subcomponents. J. Am. Chem. Soc. 1959, 81, 4387-4390.
    • (1959) J. Am. Chem. Soc. , vol.81 , pp. 4387-4390
    • Liu, W.1    Strong, F.2
  • 33
    • 0014737396 scopus 로고
    • Antimycin a components. 1. Isolation and biological activity
    • Kluepfel, D.; Sehgal, S.; Vezina, C. Antimycin a components. 1. Isolation and biological activity. J. Antibiot. (Tokyo) 1970, 23, 75-80.
    • (1970) J. Antibiot. (Tokyo) , vol.23 , pp. 75-80
    • Kluepfel, D.1    Sehgal, S.2    Vezina, C.3
  • 35
    • 0014238876 scopus 로고
    • Respiratory chain of antimycin a-producing Streptomyces antibioticus
    • Rehacek, Z.; Ramankutty, M.; Kozova, J. Respiratory chain of antimycin a-producing Streptomyces antibioticus. Appl. Microbiol. 1968, 16, 29-32.
    • (1968) Appl. Microbiol. , vol.16 , pp. 29-32
    • Rehacek, Z.1    Ramankutty, M.2    Kozova, J.3
  • 36
    • 0025243736 scopus 로고
    • Liquid chromatography-thermospray mass spectrometric study of n-acylamino dilactones and 4-butyrolactones derived from antimycin a
    • Abidi, S.L.; Ha, S.C.; Rosen, R.T. Liquid chromatography-thermospray mass spectrometric study of n-acylamino dilactones and 4-butyrolactones derived from antimycin a. J. Chromatogr. 1990, 552, 179-194.
    • (1990) J. Chromatogr. , vol.552 , pp. 179-194
    • Abidi, S.L.1    Ha, S.C.2    Rosen, R.T.3
  • 37
    • 0015314631 scopus 로고
    • Conditions influencing antimycin production by a Streptomyces species grown in chemically defined medium
    • Neft, N.; Farley, T. Conditions influencing antimycin production by a Streptomyces species grown in chemically defined medium. Antimicrob. Agents Chemother. 1972, 1, 274-276.
    • (1972) Antimicrob. Agents Chemother. , vol.1 , pp. 274-276
    • Neft, N.1    Farley, T.2
  • 38
    • 84865265539 scopus 로고    scopus 로고
    • Biosynthetic pathway for high structural diversity of a common dilactone core in antimycin production
    • Yan, Y.; Zhang, L.; Ito, T.; Qu, X.; Asakawa, Y.; Awakawa, T.; Abe, I.; Liu, W. Biosynthetic pathway for high structural diversity of a common dilactone core in antimycin production. Org. Lett. 2012, 14, 4142-4145.
    • (2012) Org. Lett. , vol.14 , pp. 4142-4145
    • Yan, Y.1    Zhang, L.2    Ito, T.3    Qu, X.4    Asakawa, Y.5    Awakawa, T.6    Abe, I.7    Liu, W.8
  • 40
    • 17544372171 scopus 로고    scopus 로고
    • New butenolides from two marine streptomycetes
    • Mukku, V.; Speitling, M.; Laatsch, H.; Helmke, E. New butenolides from two marine streptomycetes. J. Nat. Prod. 2000, 63, 1570-1572.
    • (2000) J. Nat. Prod. , vol.63 , pp. 1570-1572
    • Mukku, V.1    Speitling, M.2    Laatsch, H.3    Helmke, E.4
  • 41
    • 77649208017 scopus 로고    scopus 로고
    • Anti-parasitic compounds from Streptomyces sp strains isolated from mediterranean sponges
    • Pimentel-Elardo, S.; Kozytska, S.; Bugni, T.; Ireland, C.; Moll, H.; Hentschel, U. Anti-parasitic compounds from Streptomyces sp strains isolated from mediterranean sponges. Mar. Drugs 2010, 8, 373-380.
    • (2010) Mar. Drugs , vol.8 , pp. 373-380
    • Pimentel-Elardo, S.1    Kozytska, S.2    Bugni, T.3    Ireland, C.4    Moll, H.5    Hentschel, U.6
  • 42
    • 4844221703 scopus 로고    scopus 로고
    • Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum
    • Martinelli, D.; Grossmann, G.; Sequin, U.; Brandl, H.; Bachofen, R. Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum. BMC Microbiol. 2004, 4, 25.
    • (2004) BMC Microbiol. , vol.4 , pp. 25
    • Martinelli, D.1    Grossmann, G.2    Sequin, U.3    Brandl, H.4    Bachofen, R.5
  • 44
    • 0026709964 scopus 로고
    • Autoregulatory factors and communication in actinomycetes
    • Horinouchi, S.; Beppu, T. Autoregulatory factors and communication in actinomycetes. Annu. Rev. Microbiol. 1992, 46, 377-398.
    • (1992) Annu. Rev. Microbiol. , vol.46 , pp. 377-398
    • Horinouchi, S.1    Beppu, T.2
  • 45
    • 0036007872 scopus 로고    scopus 로고
    • Marine natural products
    • DOI 10.1039/b009029h
    • Faulkner, D. Marine natural products. Nat. Prod. Rep. 2002, 19, 1-48. (Pubitemid 34140331)
    • (2002) Natural Product Reports , vol.19 , Issue.1 , pp. 1-48
    • Faulkner, D.J.1
  • 48
    • 84863993358 scopus 로고    scopus 로고
    • Volatile lactones from streptomycetes arise via the antimycin biosynthetic pathway
    • Riclea, R.; Aigle, B.; Leblond, P.; Schoenian, I.; Spiteller, D.; Dickschat, J.S. Volatile lactones from streptomycetes arise via the antimycin biosynthetic pathway. Chembiochem 2012, 13, 1635-1644.
    • (2012) Chembiochem , vol.13 , pp. 1635-1644
    • Riclea, R.1    Aigle, B.2    Leblond, P.3    Schoenian, I.4    Spiteller, D.5    Dickschat, J.S.6
  • 49
    • 84903531880 scopus 로고    scopus 로고
    • Sourceforge Project Website. Available online: (accessed on 22 April 2012)
    • Sourceforge Project Website. Available online: http://sourceforge.net/ projects/mzmine/ (accessed on 22 April 2012).
  • 50
    • 84901421268 scopus 로고    scopus 로고
    • Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans
    • Viegelmann, C.; Parker, J.; Ooi, T.; Clements, C.; Abbott, G.; Young, L.; Kennedy, J.; Dobson, A.D.W.; Edrada-Ebel, R. Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans. Mar. Drugs 2014, 12, 2937-2952.
    • (2014) Mar. Drugs , vol.12 , pp. 2937-2952
    • Viegelmann, C.1    Parker, J.2    Ooi, T.3    Clements, C.4    Abbott, G.5    Young, L.6    Kennedy, J.7    Dobson, A.D.W.8    Edrada-Ebel, R.9
  • 51
    • 0035940721 scopus 로고    scopus 로고
    • Chromatographic analysis of plant sterols in foods and vegetable oils
    • DOI 10.1016/S0021-9673(01)00946-3, PII S0021967301009463
    • Abidi, S.L. Chromatographic analysis of plant sterols in foods and vegetable oils. J. Chromatogr. A 2001, 935, 173-201. (Pubitemid 33044646)
    • (2001) Journal of Chromatography A , vol.935 , Issue.1-2 , pp. 173-201
    • Abidi, S.L.1
  • 52
    • 0001348852 scopus 로고
    • Relation between structure and retention time of sterols in gas chromatography
    • Patterson, G.W. Relation between structure and retention time of sterols in gas chromatography. Anal. Chem. 1971, 43, 1165-1170.
    • (1971) Anal. Chem. , vol.43 , pp. 1165-1170
    • Patterson, G.W.1
  • 53
    • 51249187017 scopus 로고
    • Separation of pairs of C-24 epimeric sterols by glass capillary gas liquid chromatography
    • Thompson, R.H.; Patterson, G.W.; Thompson, M.; Slover, H.T. Separation of pairs of C-24 epimeric sterols by glass capillary gas liquid chromatography. Lipids 1981, 16, 694-699.
    • (1981) Lipids , vol.16 , pp. 694-699
    • Thompson, R.H.1    Patterson, G.W.2    Thompson, M.3    Slover, H.T.4
  • 54
    • 0342733231 scopus 로고
    • The synthesis from thujaketone of some new hydroterpenoids
    • Werner, J.; Bogert, M.T. The synthesis from thujaketone of some new hydroterpenoids. J. Org. Chem. 1938, 3, 578-587.
    • (1938) J. Org. Chem. , vol.3 , pp. 578-587
    • Werner, J.1    Bogert, M.T.2
  • 55
    • 80155174922 scopus 로고    scopus 로고
    • Khatmiamycin, a motility inhibitor and zoosporicide against the grapevine downy mildew pathogen Plasmopara viticola from Streptomyces sp. Ank313
    • Abdalla, M.A.; Win, H.Y.; Islam, M.T.; von Tiedemann, A.; Schüffler, A.; Laatsch, H. Khatmiamycin, a motility inhibitor and zoosporicide against the grapevine downy mildew pathogen Plasmopara viticola from Streptomyces sp. Ank313. J. Antibiot. (Tokyo) 2011, 64, 655-659.
    • (2011) J. Antibiot. (Tokyo) , vol.64 , pp. 655-659
    • Abdalla, M.A.1    Win, H.Y.2    Islam, M.T.3    Von Tiedemann, A.4    Schüffler, A.5    Laatsch, H.6
  • 56
    • 0034739119 scopus 로고    scopus 로고
    • Fatty acid amides from freshwater green alga Rhizoclonium hieroglyphicum
    • Dembitsky, V.M.; Shkrob, I.; Rozentsvet, O.A. Fatty acid amides from freshwater green alga Rhizoclonium hieroglyphicum. Phytochemistry 2000, 54, 965-967.
    • (2000) Phytochemistry , vol.54 , pp. 965-967
    • Dembitsky, V.M.1    Shkrob, I.2    Rozentsvet, O.A.3
  • 57
    • 77955562439 scopus 로고    scopus 로고
    • A guide to successful bioprospecting: Informed by actinobacterial systematics
    • Goodfellow, M.; Fiedler, H.P. A guide to successful bioprospecting: Informed by actinobacterial systematics. Antonie Van Leeuwenhoek 2010, 98, 119-142.
    • (2010) Antonie Van Leeuwenhoek , vol.98 , pp. 119-142
    • Goodfellow, M.1    Fiedler, H.P.2
  • 58
    • 34249817099 scopus 로고    scopus 로고
    • Colorimetric broth microdilution method for the antifungal screening of plant extracts against yeasts
    • DOI 10.1016/j.ymeth.2007.02.013, PII S1046202307000436, Natural Product Research: The Challenges Facing the Modern Researcher
    • Liu, M.; Seidel, V.; Katerere, D.R.; Gray, A.I. Colorimetric broth microdilution method for the antifungal screening of plant extracts against yeasts. Methods 2007, 42, 325-329. (Pubitemid 46856866)
    • (2007) Methods , vol.42 , Issue.4 , pp. 325-329
    • Liu, M.1    Seidel, V.2    Katerere, D.R.3    Gray, A.I.4
  • 59
    • 34249800918 scopus 로고    scopus 로고
    • Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals
    • DOI 10.1016/j.ymeth.2007.01.006, PII S1046202307000096, Natural Product Research: The Challenges Facing the Modern Researcher
    • Sarker, S.D.; Nahar, L.; Kumarasamy, Y. Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals. Methods 2007, 42, 321-324. (Pubitemid 46856865)
    • (2007) Methods , vol.42 , Issue.4 , pp. 321-324
    • Sarker, S.D.1    Nahar, L.2    Kumarasamy, Y.3
  • 63
  • 66
    • 0032898961 scopus 로고    scopus 로고
    • Evidence that the extracytoplasmic function sigma factor sigma(E) is required for normal cell wall structure in Streptomyces coelicolor A3(2)
    • Paget, M.S.; Chamberlin, L.; Atrih, A.; Foster, S.J.; Buttner, M.J. Evidence that the extracytoplasmic function sigma factor sigmae is required for normal cell wall structure in Streptomyces coelicolor a3(2). J. Bacteriol. 1999, 181, 204-211. (Pubitemid 29013672)
    • (1999) Journal of Bacteriology , vol.181 , Issue.1 , pp. 204-211
    • Paget, M.S.B.1    Chamberlin, L.2    Atrih, A.3    Foster, S.J.4    Buttner, M.J.5
  • 67
    • 84903542461 scopus 로고    scopus 로고
    • Available online: (accessed on 25 March 2014)
    • PharmaSea. Available online: http://www.pharma-sea.eu (accessed on 25 March 2014).
  • 68
    • 84903525791 scopus 로고    scopus 로고
    • SeaBioTech. Available online: (accessed on 25 March 2014)
    • SeaBioTech. Available online: http://spider.science.strath.ac.uk/ seabiotech/ (accessed on 25 March 2014).


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