Directed differentiation of human induced pluripotent stem cells toward bone and cartilage: In vitro versus in vivo assays

Stem Cells Translational Medicine

Volumn 3, Issue 7, 2014, Pages 867-878

  Phillips, Matthew D ^a   Kuznetsov, Sergei A ^a   Cherman, Natasha ^a   Park, Kyeyoon ^b   Chen, Kevin G ^b   McClendon, Britney N ^a   Hamilton, Rebecca S ^b   McKay, Ronald D G ^c   Chenoweth, Josh G ^c   Mallon, Barbara S ^b   Robey, Pamela G ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

Author keywords

Bone; Chondrogenesis; Induced pluripotent stem cells; Osteoblast; Transplantation

Indexed keywords

ALKALINE PHOSPHATASE; ASCORBIC ACID 2 PHOSPHATE; BONE MORPHOGENETIC PROTEIN 4; BONE SIALOPROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; DEXAMETHASONE; FIBROBLAST GROWTH FACTOR 2; HERMES ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; OSTEOCALCIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; RAPAMYCIN; RETINOIC ACID; STAGE SPECIFIC EMBRYO ANTIGEN 1; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR RUNX2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BONE DEVELOPMENT; BONE MATRIX; BONE MINERALIZATION; CARTILAGE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; EMBRYONIC STEM CELL; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION ASSAY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFANT; KARYOTYPING; MESENCHYMAL STROMA CELL; MOUSE; MRNA EXPRESSION ASSAY; NONHUMAN; OSSIFICATION; OSTEOBLAST; PLURIPOTENT STEM CELL; PLURIPOTENT STEM CELL LINE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGENERATIVE MEDICINE; SKIN FIBROBLAST; STEM CELL CULTURE;

BONE; CHONDROGENESIS; INDUCED PLURIPOTENT STEM CELLS; OSTEOBLAST; TRANSPLANTATION;

AGED; AGED, 80 AND OVER; ANIMALS; BIOLOGICAL ASSAY; CELL DIFFERENTIATION; CELL LINE; CHONDROCYTES; CHONDROGENESIS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; NUCLEAR REPROGRAMMING; OSTEOBLASTS; OSTEOGENESIS; PHENOTYPE; TRANSFECTION;

EID: 84903518256     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0154     Document Type: Article

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