Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS

Biomaterials

Volumn 35, Issue 27, 2014, Pages 7786-7799

  Dang, Lan T H ^a,e,f   Feric, Nicole T ^a   Laschinger, Carol ^a   Chang, Wing Y ^a,b,c   Zhang, Boyang ^e   Wood, Geoffrey A ^d   Stanford, William L ^a,b,c   Radisic, Milica ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF GUELPH   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Adhesion; Angiopoietin 1; Apoptosis; Human pluripotent stem cells; Integrins; QHREDGS

Indexed keywords

ADHESION; CELL ADHESION; GLYCOPROTEINS; MOLECULES; PEPTIDES; STEM CELLS; SUBSTRATES;

ANGIOPOIETIN-1; EXTRACELLULAR SIGNAL-REGULATED KINASE; HUMAN-INDUCED PLURIPOTENT STEM CELLS; INTEGRIN-LINKED KINASE; INTEGRINS; PLURIPOTENT STEM CELLS; QHREDGS; SMALL MOLECULE INHIBITOR;

CELL DEATH;

ANGIOPOIETIN 1; BETA1 INTEGRIN; CASPASE 3; CASPASE 7; INTEGRIN LINKED KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OCTAMER TRANSCRIPTION FACTOR 4; PEPTIDE; QHREDGS PEPTIDE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; CASPASE; INTEGRIN-LINKED KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONJUGATION; EMBRYO; GENE EXPRESSION; GERM LAYER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LONG TERM EXPOSURE; MESODERM; NERVE CELL; NORMAL HUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STEM CELL CULTURE; STEM CELL EXPANSION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL COUNT; CELL CULTURE; CELL SIZE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; FEEDER CELL; METABOLISM; MOUSE; PROCEDURES; TIME;

ANGIOPOIETIN-1; ANIMALS; ANTIGENS, CD29; APOPTOSIS; CASPASES; CELL ADHESION; CELL COUNT; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEEDER CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; PEPTIDES; PROTEIN-SERINE-THREONINE KINASES; TIME FACTORS;

EID: 84903488615     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.018     Document Type: Article

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