Retraction: Regulation of cell proliferation and migration by p62 through stabilization of Twist1 (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (9241–9246) DOI: 10.1073/pnas.1322913111);Regulation of cell proliferation and migration by p62 through stabilization of Twist1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 25, 2014, Pages 9241-9246

  Qiang, Lei ^a   Zhao, Baozhong ^a   Ming, Mei ^a   Wang, Ning ^b   He, Tong Chuan ^b   Hwang, Seungmin ^c   Thorburn, Andrew ^d   He, Yu Ying ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Melanoma; Proteasome; Skin cancer; SQSTM1; Ubiquitination

Indexed keywords

PROTEIN P62; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TWIST1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL MIGRATION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; EPITHELIUM; GENE TARGETING; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MEDIATOR; METASTASIS; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; RECEPTOR UPREGULATION; TUMOR GROWTH; TUMOR XENOGRAFT; UBIQUITINATION;

MELANOMA; PROTEASOME; SKIN CANCER; SQSTM1; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HEAT-SHOCK PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MALE; MICE; MICE, KNOCKOUT; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; NUCLEAR PROTEINS; PROTEIN STABILITY; TWIST TRANSCRIPTION FACTOR;

EID: 84903481496     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.2313213120     Document Type: Erratum

References (46)

1. Klionsky DJ (2007) Autophagy: From phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8(11):931-937.
2. Mizushima N, Levine B, Cuervo AM, Klionsky DJ (2008) Autophagy fights disease through cellular self-digestion. Nature 451(7182):1069-1075. (Pubitemid 351317450)
3. Choi AM, Ryter SW, Levine B (2013) Autophagy in human health and disease. N Engl J Med 368(19):1845-1846.
4. White E (2012) Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer 12(6):401-410.
5. Bjørkøy G, et al. (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171(4):603-614. (Pubitemid 41668720)
6. Pankiv S, et al. (2007) p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 282(33):24131-24145. (Pubitemid 47328003)
7. Moscat J, Diaz-Meco MT (2009) p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 137(6):1001-1004.
8. Moscat J, Diaz-Meco MT (2012) p62: A versatile multitasker takes on cancer. Trends Biochem Sci 37(6):230-236.
9. Mathew R, et al. (2009) Autophagy suppresses tumorigenesis through elimination of p62. Cell 137(6):1062-1075.
10. Duran A, et al. (2008) The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. Cancer Cell 13(4):343-354. (Pubitemid 351446193)
11. Inami Y, et al. (2011) Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol 193(2):275-284.
12. Komatsu M, et al. (2010) The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 12(3):213-223.
13. Lau A, et al. (2010) A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between Keap1 and p62. Mol Cell Biol 30(13):3275-3285.
14. Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis. Dev Cell 14(6):818-829. (Pubitemid 351757205)
15. Eckert MA, et al. (2011) Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell 19(3):372-386.
16. Yang J, et al. (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117(7):927-939. (Pubitemid 38798858)
17. Franco HL, Casasnovas J, Rodríguez-Medina JR, Cadilla CL (2011) Redundant or separate entities? - roles of Twist1 and Twist2 as molecular switches during gene transcription. Nucleic Acids Res 39(4):1177-1186.
18. Lander R, Nordin K, LaBonne C (2011) The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1. J Cell Biol 194(1):17-25.
19. Kabeya Y, et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19(21):5720-5728.
20. Klionsky DJ, et al. (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4(2):151-175.
21. Bolós V, et al. (2003) The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors. J Cell Sci 116(Pt 3):499-511. (Pubitemid 36231290)
22. Batlle E, et al. (2000) The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2(2):84-89.
23. Vesuna F, van Diest P, Chen JH, Raman V (2008) Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer. Biochem Biophys Res Commun 367(2):235-241.
24. Gravdal K, Halvorsen OJ, Haukaas SA, Akslen LA (2007) A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer. Clin Cancer Res 13(23):7003-7011. (Pubitemid 350276881)
25. Itakura E, Mizushima N (2011) p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J Cell Biol 192(1):17-27.
26. Korolchuk VI, Mansilla A, Menzies FM, Rubinsztein DC (2009) Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates. Mol Cell 33(4):517-527.
27. Hiyama H, et al. (1999) Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome. J Biol Chem 274(39):28019-28025.
28. Chen L, Madura K (2002) Rad23 promotes the targeting of proteolytic substrates to the proteasome. Mol Cell Biol 22(13):4902-4913. (Pubitemid 34620423)
29. Farmer LM, et al. (2010) The RAD23 family provides an essential connection between the 26S proteasome and ubiquitylated proteins in Arabidopsis. Plant Cell 22(1):124-142.
30. Seibenhener ML, et al. (2004) Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol Cell Biol 24(18):8055-8068. (Pubitemid 39167456)
31. Laursen KB, Mielke E, Iannaccone P, Füchtbauer EM (2007) Mechanism of transcriptional activation by the proto-oncogene Twist1. J Biol Chem 282(48):34623-34633. (Pubitemid 350232411)
32. Onder TT, et al. (2008) Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68(10):3645-3654.
33. Kao YC, et al. (2010) Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition. Mol Cell Biol 30(20):4767-4785.
34. Kiyono K, et al. (2009) Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells. Cancer Res 69(23):8844-8852.
35. Puisieux A, Valsesia-Wittmann S, Ansieau S (2006) A twist for survival and cancer progression. Br J Cancer 94(1):13-17. (Pubitemid 43088534)
36. Ansieau S, et al. (2008) Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell 14(1):79-89. (Pubitemid 351890463)
37. Šošić D, Richardson JA, Yu K, Ornitz DM, Olson EN (2003) Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell 112(2):169-180. (Pubitemid 36144107)
38. Cheng GZ, et al. (2008) Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. J Biol Chem 283(21):14665-14673.
39. Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML (2008) A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development. Development 135(11):1903-1911. (Pubitemid 351943355)
40. Lv Q, et al. (2012) DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer. Cancer Res 72(13):3238-3250.
41. Babu JR, Geetha T, Wooten MW (2005) Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation. J Neurochem 94(1):192-203. (Pubitemid 40911405)
42. Inoue D, et al. (2012) Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma. Cancer Sci 103(4):760-766.
43. Thompson HG, Harris JW, Wold BJ, Lin F, Brody JP (2003) p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells. Oncogene 22(15):2322-2333. (Pubitemid 36566787)
44. Rolland P, et al. (2007) The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease. Endocr Relat Cancer 14(1):73-80. (Pubitemid 47521723)
45. Belaid A, et al. (2013) Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res 73(14):4311-4322.
46. Belaid A, et al. (2014) Autophagy and SQSTM1 on the RHOA(d) again: Emerging roles of autophagy in the degradation of signaling proteins. Autophagy 10(2):201-208.