Low density lipoprotein receptor class A repeats are O-glycosylated in linker regions

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17312-17324

  Pedersen, Nis Borbye ^a   Wang, Shengjun ^a   Narimatsu, Yoshiki ^a   Yang, Zhang ^a   Halim, Adnan ^a   Schjoldager, Katrine Ter Borch Gram ^a   Madsen, Thomas Daugbjerg ^a   Seidah, Nabil G ^b   Bennett, Eric Paul ^a   Levery, Steven B ^a   Clausen, Henrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; ENZYMES; GLYCOSYLATION;

CHOLESTEROL HOMEOSTASIS; CYSTEINE RESIDUES; HOMOLOGOUS RECEPTORS; HYPERCHOLESTEROLEMIA; LOW DENSITY LIPOPROTEIN RECEPTORS; STABLE EXPRESSION; TRANS-MEMBRANE PROTEINS; WILD-TYPE CELLS;

ESTERIFICATION;

GLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR; N ACETYLGALACTOSAMINYLTRANSFERASE; N ACETYLGALACTOSAMINYLTRANSFERASE T1; N ACETYLGALACTOSAMINYLTRANSFERASE T11; N ACETYLGALACTOSAMINYLTRANSFERASE T12; N ACETYLGALACTOSAMINYLTRANSFERASE T16; N ACETYLGALACTOSAMINYLTRANSFERASE T2; N ACETYLGALACTOSAMINYLTRANSFERASE T3; O GLYCAN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL LINE; CONTROLLED STUDY; DNA STRUCTURE; ENZYME ASSAY; GENE INACTIVATION; GENETIC CONSERVATION; GLYCOSYLATION AND DEGLYCOSYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LIGAND BINDING; LINKER REGION; LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A REPEAT; MOLECULAR DYNAMICS; NONHUMAN; O GLYCOSYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEOMICS; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; WILD TYPE; XENOPUS;

GALNT; GLYCOSYLATION; GLYCOSYLTRANSFERASE; LECTIN; LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LPR); LOW DENSITY LIPOPROTEIN (LDL); O-GLYCAN; ZINC FINGER NUCLEASE;

AMINO ACID MOTIFS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GLYCOSYLATION; HEK293 CELLS; HUMANS; OOCYTES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LDL; REPETITIVE SEQUENCES, AMINO ACID; SIALYLTRANSFERASES; XENOPUS LAEVIS;

EID: 84903480472     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.545053     Document Type: Article

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