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Volumn 10, Issue 6, 2014, Pages

Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia

(27)  Juraeva, Dilafruz a   Haenisch, Britta b,c,d   Zapatka, Marc a   Frank, Josef e   Witt, Stephanie H e   Mühleisen, Thomas W c,f   Treutlein, Jens e   Strohmaier, Jana e   Meier, Sandra e,g   Degenhardt, Franziska c   Giegling, Ina h,i   Ripke, Stephan j,k   Leber, Markus c   Lange, Christoph b,c,l   Schulze, Thomas G m   Mössner, Rainald c   Nenadic, Igor n   Sauer, Heinrich n   Rujescu, Dan h,i   Maier, Wolfgang c   more..


Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR CTCF; TRANSCRIPTION FACTOR FOXP2;

EID: 84903440660     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004345     Document Type: Article
Times cited : (41)

References (63)
  • 1
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • Manolio TA, Brooks LD, Collins FS, (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118: 1590-1605.
    • (2008) J Clin Invest , vol.118 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 2
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 106: 9362-9367.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 3
    • 79751474481 scopus 로고    scopus 로고
    • Pathway-based analysis of GWAS datasets: Effective but caution required
    • Jia P, Wang L, Meltzer HY, Zhao Z, (2010) Pathway-based analysis of GWAS datasets: effective but caution required. Int J Neuropsychopharmacol 14: 567-572.
    • (2010) Int J Neuropsychopharmacol , vol.14 , pp. 567-572
    • Jia, P.1    Wang, L.2    Meltzer, H.Y.3    Zhao, Z.4
  • 5
    • 78549251736 scopus 로고    scopus 로고
    • Analysing biological pathways in genome-wide association studies
    • Wang K, Li M, Hakonarson H, (2010) Analysing biological pathways in genome-wide association studies. Nat Rev Genet 11: 843-854.
    • (2010) Nat Rev Genet , vol.11 , pp. 843-854
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 6
    • 84862499271 scopus 로고    scopus 로고
    • Pathways analysis of genomic data: Concepts, methods, and prospoects for future development
    • Ramanan VK, Shen L, Moore JH, Saykin AJ, (2012) Pathways analysis of genomic data: concepts, methods, and prospoects for future development. Trends in Genetics 28: 323-332.
    • (2012) Trends in Genetics , vol.28 , pp. 323-332
    • Ramanan, V.K.1    Shen, L.2    Moore, J.H.3    Saykin, A.J.4
  • 7
    • 53649098737 scopus 로고    scopus 로고
    • Pathway analysis of seven common diseases assessed by genome-wide association
    • Torkamani A, Topol EJ, Schork NJ, (2008) Pathway analysis of seven common diseases assessed by genome-wide association. Genomics 92: 265-272.
    • (2008) Genomics , vol.92 , pp. 265-272
    • Torkamani, A.1    Topol, E.J.2    Schork, N.J.3
  • 8
    • 58849112975 scopus 로고    scopus 로고
    • Pathways-based analysis of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
    • Askland K, Read C, Moore J, (2009) Pathways-based analysis of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission. Hum Genet 125: 63-79.
    • (2009) Hum Genet , vol.125 , pp. 63-79
    • Askland, K.1    Read, C.2    Moore, J.3
  • 9
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study datasets provides insights into the biology of bipolar disorder
    • Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, et al. (2009) Gene ontology analysis of GWA study datasets provides insights into the biology of bipolar disorder. Am J Hum Genet 85: 13-24.
    • (2009) Am J Hum Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.4    Purcell, S.M.5
  • 10
    • 78549252909 scopus 로고    scopus 로고
    • Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility
    • O'Dushlaine C, Kenny E, Heron E, Donohoe G, Gill M, et al. (2010) Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility. Mol Psychiatry 16: 286-292.
    • (2010) Mol Psychiatry , vol.16 , pp. 286-292
    • O'Dushlaine, C.1    Kenny, E.2    Heron, E.3    Donohoe, G.4    Gill, M.5
  • 11
    • 79955121427 scopus 로고    scopus 로고
    • SNP-based pathway enrichment analysis for genome-wide association studies
    • doi:10.1186/1471-2105-12-99
    • Weng L, Macciardi F, Subramanian A, Guffanti G, Potkin SG, et al. (2010) SNP-based pathway enrichment analysis for genome-wide association studies. BMC Bioinformatics 12: 99 doi:10.1186/1471-2105-12-99.
    • (2010) BMC Bioinformatics , vol.12 , pp. 99
    • Weng, L.1    Macciardi, F.2    Subramanian, A.3    Guffanti, G.4    Potkin, S.G.5
  • 12
    • 84862781043 scopus 로고    scopus 로고
    • A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia
    • Jia P, Wang L, Fanous AH, Chen X, Kendler KS, et al. (2012) A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. J Med Genet 49: 96-103.
    • (2012) J Med Genet , vol.49 , pp. 96-103
    • Jia, P.1    Wang, L.2    Fanous, A.H.3    Chen, X.4    Kendler, K.S.5
  • 13
    • 84904723024 scopus 로고    scopus 로고
    • Gene set analysis methods: Statistical models and methodological differences
    • doi:10.1093/bib/bbt002
    • Maciejewski H, (2013) Gene set analysis methods: statistical models and methodological differences. Brief Bioinform doi: 10.1093/bib/bbt002.
    • (2013) Brief Bioinform
    • Maciejewski, H.1
  • 14
    • 34249663294 scopus 로고    scopus 로고
    • Analyzing gene expression data in terms of gene sets: Methodological issues
    • Goeman JJ, Bühlmann P, (2004) Analyzing gene expression data in terms of gene sets: methodological issues. Bioinformatics 23: 980-987.
    • (2004) Bioinformatics , vol.23 , pp. 980-987
    • Goeman, J.J.1    Bühlmann, P.2
  • 16
    • 84872601462 scopus 로고    scopus 로고
    • Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways
    • Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, et al. (2013) Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways. Age 35: 235-249.
    • (2013) Age , vol.35 , pp. 235-249
    • Deelen, J.1    Uh, H.W.2    Monajemi, R.3    van Heemst, D.4    Thijssen, P.E.5
  • 17
    • 80052441156 scopus 로고    scopus 로고
    • Gene Set Analysis and Network Analysis for Genome-Wide Association Studies
    • doi:10.1101/pdb.top065581
    • Pedroso I, Breen G, (2011) Gene Set Analysis and Network Analysis for Genome-Wide Association Studies. Cold Spring Harb Protoc doi:10.1101/pdb.top065581.
    • (2011) Cold Spring Harb Protoc
    • Pedroso, I.1    Breen, G.2
  • 18
    • 84865712382 scopus 로고    scopus 로고
    • Annotation of functional variation in personal genomes using RegulomeDB
    • Boyle A, Hong E, Hariharan M, Cheng Y, Schaub M, et al. (2012) Annotation of functional variation in personal genomes using RegulomeDB. Genome Res 22: 1790-1797.
    • (2012) Genome Res , vol.22 , pp. 1790-1797
    • Boyle, A.1    Hong, E.2    Hariharan, M.3    Cheng, Y.4    Schaub, M.5
  • 19
    • 77956192274 scopus 로고    scopus 로고
    • Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data
    • Jia P, Wang L, Meltzer HY, Zhao Z, (2010) Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophr Res 122: 38-42.
    • (2010) Schizophr Res , vol.122 , pp. 38-42
    • Jia, P.1    Wang, L.2    Meltzer, H.Y.3    Zhao, Z.4
  • 20
    • 84878825442 scopus 로고    scopus 로고
    • Pathway analysis of a genome-wide association study in schizophrenia
    • Lee YH, Kim JH, Song GG, (2013) Pathway analysis of a genome-wide association study in schizophrenia. Gene 525: 107-115.
    • (2013) Gene , vol.525 , pp. 107-115
    • Lee, Y.H.1    Kim, J.H.2    Song, G.G.3
  • 21
    • 77953123145 scopus 로고    scopus 로고
    • Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data
    • Chen LS, Hutter CM, Potter JD, Liu Y, Prentice RL, et al. (2010) Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data. Am J Hum Genet 86: 860-871.
    • (2010) Am J Hum Genet , vol.86 , pp. 860-871
    • Chen, L.S.1    Hutter, C.M.2    Potter, J.D.3    Liu, Y.4    Prentice, R.L.5
  • 22
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-Based Approaches for Analysis of Genomewide Association Studies
    • Wang K, Li M, Bucan M, (2007) Pathway-Based Approaches for Analysis of Genomewide Association Studies. Am J Hum Genet 81: 1278-1283.
    • (2007) Am J Hum Genet , vol.81 , pp. 1278-1283
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 23
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study datasets provides insights into the biology of bipolar disorder
    • Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, et al. (2009) Gene ontology analysis of GWA study datasets provides insights into the biology of bipolar disorder. Am J Hum Genet 85: 13-24.
    • (2009) Am J Hum Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.4    Purcell, S.M.5
  • 24
    • 84876896913 scopus 로고    scopus 로고
    • Structure and function of the β subunit of voltage-gated Ca(2+) channels
    • Buraei Z, Yang J, (2013) Structure and function of the β subunit of voltage-gated Ca(2+) channels. Biochim Biophys Acta 1828: 1530-1540.
    • (2013) Biochim Biophys Acta , vol.1828 , pp. 1530-1540
    • Buraei, Z.1    Yang, J.2
  • 25
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Erratum in: Lancet 381: 1360
    • Cross-Disorder Group of the Psychiatric Genomics Consortium (2010) Smoller JW, Craddock N, Kendler K, Lee PH, et al. (2010) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381: 1371-1379. Erratum in: Lancet 381: 1360.
    • Lancet , vol.381 , pp. 1371-1379
    • Smoller, J.W.1    Craddock, N.2    Kendler, K.3    Lee, P.H.4
  • 26
    • 79955473843 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar I disorder in the Han Chinese population
    • Lee MT, Chen CH, Lee CS, Chen CC, Chong MY, et al. (2011) Genome-wide association study of bipolar I disorder in the Han Chinese population. Mol Psychiatry 16: 548-556.
    • (2011) Mol Psychiatry , vol.16 , pp. 548-556
    • Lee, M.T.1    Chen, C.H.2    Lee, C.S.3    Chen, C.C.4    Chong, M.Y.5
  • 27
    • 34247385160 scopus 로고    scopus 로고
    • Regulation of Cav1.2 current: Interaction with intracellular molecules
    • Kobayashi T, Yamada Y, Fukao M, Tsutsuura M, Tohse N, (2007) Regulation of Cav1.2 current: interaction with intracellular molecules. J Pharmacol Sci 103: 347-353.
    • (2007) J Pharmacol Sci , vol.103 , pp. 347-353
    • Kobayashi, T.1    Yamada, Y.2    Fukao, M.3    Tsutsuura, M.4    Tohse, N.5
  • 28
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group (2013) Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 43: 977-983.
    • (2013) Nat Genet , vol.43 , pp. 977-983
  • 29
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer MD, et al. (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 40: 1056-1058.
    • (2008) Nat Genet , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3    Jones, I.R.4    Ruderfer, M.D.5
  • 30
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011) Ripke S, Sanders AR, Kendler KS, Levinson DF, et al. (2011) Genome-wide association study identifies five new schizophrenia loci. Nat Gen 43: 969-976.
    • (2011) Nat Gen , vol.43 , pp. 969-976
    • Ripke, S.1    Sanders, A.R.2    Kendler, K.S.3    Levinson, D.F.4
  • 31
    • 77954510735 scopus 로고    scopus 로고
    • The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
    • Green EK, Grozeva D, Jones I, Jones L, Kirov G, et al. (2010) The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry 15: 1016-1022.
    • (2010) Mol Psychiatry , vol.15 , pp. 1016-1022
    • Green, E.K.1    Grozeva, D.2    Jones, I.3    Jones, L.4    Kirov, G.5
  • 32
    • 84857048120 scopus 로고    scopus 로고
    • Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport
    • Houghton FJ, Bellingham SA, Hill AF, Bourges D, Ang DK, et al. (2012) Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport. Exp Cell Res 318: 464-477.
    • (2012) Exp Cell Res , vol.318 , pp. 464-477
    • Houghton, F.J.1    Bellingham, S.A.2    Hill, A.F.3    Bourges, D.4    Ang, D.K.5
  • 33
    • 33846149648 scopus 로고    scopus 로고
    • DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1
    • Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, et al. (2007) DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. J Neurosci 27: 15-26.
    • (2007) J Neurosci , vol.27 , pp. 15-26
    • Taya, S.1    Shinoda, T.2    Tsuboi, D.3    Asaki, J.4    Nagai, K.5
  • 34
    • 84871398317 scopus 로고    scopus 로고
    • CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice
    • Guo Y, Monahan K, Wu H, Gertz J, Varley KE, et al. (2012) CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice. Proc Natl Acad Sci U S A 109: 21081-21086.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 21081-21086
    • Guo, Y.1    Monahan, K.2    Wu, H.3    Gertz, J.4    Varley, K.E.5
  • 35
    • 84861917541 scopus 로고    scopus 로고
    • Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of protocadherin-α gene expression
    • Monahan K, Rudnick ND, Kehayova PD, Pauli F, Newberry KM, et al. (2012) Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of protocadherin-α gene expression. Proc Natl Acad Sci U S A 109: 9125-9130.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 9125-9130
    • Monahan, K.1    Rudnick, N.D.2    Kehayova, P.D.3    Pauli, F.4    Newberry, K.M.5
  • 36
    • 67549119096 scopus 로고    scopus 로고
    • CTCF: Master weaver of the genome
    • Phillips JE, Corces VG, (2009) CTCF: master weaver of the genome. Cell 137: 1194-1211.
    • (2009) Cell , vol.137 , pp. 1194-1211
    • Phillips, J.E.1    Corces, V.G.2
  • 37
    • 84865724573 scopus 로고    scopus 로고
    • CTCF is required for neural development and stochastic expression of clustered Pcdh genes in neurons
    • Hirayama T, Tarusawa E, Yoshimura Y, Galjart N, Yagi T, (2012) CTCF is required for neural development and stochastic expression of clustered Pcdh genes in neurons. Cell Rep 2: 345-357.
    • (2012) Cell Rep , vol.2 , pp. 345-357
    • Hirayama, T.1    Tarusawa, E.2    Yoshimura, Y.3    Galjart, N.4    Yagi, T.5
  • 39
    • 57649186936 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: Preliminary evidence
    • Gregório SP, Sallet PC, Do KA, Lin E, Gattaz WF, Dias-Neto E, (2009) Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Psychiatry Res 165: 1-9.
    • (2009) Psychiatry Res , vol.165 , pp. 1-9
    • Gregório, S.P.1    Sallet, P.C.2    Do, K.A.3    Lin, E.4    Gattaz, W.F.5    Dias-Neto, E.6
  • 40
    • 9944230432 scopus 로고    scopus 로고
    • Identification, expression analysis amd polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions
    • Matsuzaka Y, Okamoto K, Mabuchi T, Iizuki M, Ozawa A, et al. (2004) Identification, expression analysis amd polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions. Gene 343: 291-304.
    • (2004) Gene , vol.343 , pp. 291-304
    • Matsuzaka, Y.1    Okamoto, K.2    Mabuchi, T.3    Iizuki, M.4    Ozawa, A.5
  • 41
    • 0025814801 scopus 로고
    • Arginyl-glycyl-aspartic acid (RGD): A cell adhesion motif
    • D'Souza SE, Ginsberg MH, Plow EF, (1991) Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif. Trens Biochem Sci 16: 246-250.
    • (1991) Trens Biochem Sci , vol.16 , pp. 246-250
    • D'Souza, S.E.1    Ginsberg, M.H.2    Plow, E.F.3
  • 42
    • 79958003661 scopus 로고    scopus 로고
    • Genetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia
    • Jamadar S, Powers NR, Meda SA, Gelernter J, Gruen JR, (2011) Genetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia. Schizophr Res 129: 141-148.
    • (2011) Schizophr Res , vol.129 , pp. 141-148
    • Jamadar, S.1    Powers, N.R.2    Meda, S.A.3    Gelernter, J.4    Gruen, J.R.5
  • 43
    • 84874906262 scopus 로고    scopus 로고
    • FoxP2 is significantly associated with schizophrenia and major depression in the Chinese Han Population
    • Li T, Zeng Z, Zhao Q, Wang T, Huang K, et al. (2012) FoxP2 is significantly associated with schizophrenia and major depression in the Chinese Han Population. World J Biol Psychiatry 14: 146-150.
    • (2012) World J Biol Psychiatry , vol.14 , pp. 146-150
    • Li, T.1    Zeng, Z.2    Zhao, Q.3    Wang, T.4    Huang, K.5
  • 45
    • 0033591008 scopus 로고    scopus 로고
    • Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site
    • Nakatani K, Sakaue H, Thompson DA, Weigel RJ, Roth RA, (1999) Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site. Biochem Biophys Res Commun 257: 906-910.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 906-910
    • Nakatani, K.1    Sakaue, H.2    Thompson, D.A.3    Weigel, R.J.4    Roth, R.A.5
  • 46
    • 84859609280 scopus 로고    scopus 로고
    • Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons
    • doi:10.1371/journal.pone.0032715
    • Diez H, Garrido JJ, Wandosell F, (2012) Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons. PLoS ONE 7: e32715 doi:10.1371/journal.pone.0032715.
    • (2012) PLoS ONE , vol.7
    • Diez, H.1    Garrido, J.J.2    Wandosell, F.3
  • 48
    • 84866427260 scopus 로고    scopus 로고
    • Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe
    • Genetic Risk and Outcome in Psychosis (GROUP Investigators)
    • Rietschel M, Mattheisen M, Degenhardt F, (2012) Genetic Risk and Outcome in Psychosis (GROUP Investigators) (2012) Mühleisen TW, et al. (2012) Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Mol Psychiatry 17: 906-917.
    • (2012) Mol Psychiatry , vol.17 , pp. 906-917
    • Rietschel, M.1    Mattheisen, M.2    Degenhardt, F.3    Mühleisen, T.W.4
  • 49
  • 50
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, et al. (2009) Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 460: 753-757.
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5
  • 51
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.R.5
  • 53
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5
  • 54
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology
    • The Gene Ontology Consortium
    • The Gene Ontology Consortium Gene ontology: tool for the unification of biology. Nat Genet 25: 25-29.
    • Nat Genet , vol.25 , pp. 25-29
  • 55
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • Kanehisa M, Goto S, (2010) KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 28: 27-30.
    • (2010) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 56
  • 57
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y, (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B Stat Methodol 57: 289-300.
    • (1995) J R Stat Soc Ser B Stat Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 58
    • 39149099505 scopus 로고    scopus 로고
    • Multiple testing on the directed acyclic graph of gene ontology
    • Goeman JJ, Mansmann U, (2008) Multiple testing on the directed acyclic graph of gene ontology. Bioinformatics 24: 537-544.
    • (2008) Bioinformatics , vol.24 , pp. 537-544
    • Goeman, J.J.1    Mansmann, U.2
  • 59
    • 84894557694 scopus 로고    scopus 로고
    • Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci
    • doi:10.1038/mp.2013.2
    • Børglum AD, Demontis D, Grove J, Pallesen J, Hollegaard MV, et al. (2013) Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Mol Psychiatry 2013doi: 10.1038/mp.2013.2.
    • (2013) Mol Psychiatry , vol.2013
    • Børglum, A.D.1    Demontis, D.2    Grove, J.3    Pallesen, J.4    Hollegaard, M.V.5
  • 60
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium
    • Genomes Project Consortium (2010) Abecasis GR, Altshuler D, Auton A, Brooks LD, et al. (2010) A map of human genome variation from population-scale sequencing. Nature 467: 1061-1073.
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Abecasis, G.R.1    Altshuler, D.2    Auton, A.3    Brooks, L.D.4
  • 61
    • 57249114505 scopus 로고    scopus 로고
    • SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
    • Johnson A, Handsaker R, Pulit S, Nizzari M, O'Donnell C, et al. (2008) SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 24: 2938-2939.
    • (2008) Bioinformatics , vol.24 , pp. 2938-2939
    • Johnson, A.1    Handsaker, R.2    Pulit, S.3    Nizzari, M.4    O'Donnell, C.5
  • 63
    • 68149165614 scopus 로고    scopus 로고
    • Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
    • Kumar P, Henikoff S, Ng PC, (2009) Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc 4: 1073-1081.
    • (2009) Nat Protoc , vol.4 , pp. 1073-1081
    • Kumar, P.1    Henikoff, S.2    Ng, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.