Genetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia

Schizophrenia Research

Volumn 129, Issue 2-3, 2011, Pages 141-148

  Jamadar, S ^a   Powers, N R ^b,d,e   Meda, S A ^a,c   Gelernter, J ^b,d   Gruen, J R ^b,d,e   Pearlson, G D ^a,b  

^a INSTITUTE OF LIVING   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d YALE UNIVERSITY   (United States)

^e VA CT Healthcare Center   (United States)

Author keywords

Dyslexia genes; Gray matter; Independent component analysis; Reading; Schizophrenia

Indexed keywords

TRANSCRIPTION FACTOR FOXP2;

ADULT; AMYGDALOID NUCLEUS; ANTERIOR CEREBELLUM; ARTICLE; BRAIN REGION; CEREBELLUM; CEREBELLUM VERMIS; CEREBELLUM VERMIS PYRAMID; CLINICAL ARTICLE; CONTROLLED STUDY; CULMEN; CUNEUS; DCDC2 GENE; DYSLEXIA; DYX1C1 GENE; FEMALE; FOXP2 GENE; FUSIFORM GYRUS; GENE; GENOTYPE; GRAY MATTER; HETEROZYGOTE; HUMAN; INFERIOR FRONTAL GYRUS; INFERIOR OCCIPITAL GYRUS; INFERIOR PARIETAL LOBULE; INFERIOR TEMPORAL GYRUS; INSULA; KIAA0319 GENE; LANGUAGE DISABILITY; LEFT HEMISPHERE; LINGUAL GYRUS; MALE; MIDDLE FRONTAL GYRUS; MIDDLE OCCIPITAL GYRUS; MIDDLE TEMPORAL GYRUS; MIDDLE TEMPORAL POLE; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL GYRUS; OCCIPITAL LOBE; PARAHIPPOCAMPAL GYRUS; POSTCENTRAL GYRUS; POSTERIOR CINGULATE; PRECUNEUS; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; RIGHT HEMISPHERE; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SUPERIOR FRONTAL GYRUS; SUPERIOR PARIETAL LOBULE; SUPERIOR TEMPORAL GYRUS; SUPERIOR TEMPORAL POLE; TTRAP GENE; UNCUS; VOXEL BASED MORPHOMETRY;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; DNA MUTATIONAL ANALYSIS; FEMALE; FUNCTIONAL LATERALITY; GENOTYPE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LANGUAGE; MAGNETIC RESONANCE IMAGING; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; SCHIZOPHRENIA; YOUNG ADULT;

EID: 79958003661     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.03.027     Document Type: Article

References (36)

1. Akbarian S., Kim J.J., Potkin S.G., Hetrick W.P., Bunney W.E., Jone E.G. Maldistribution of interstitial neurons in prefrontal white matter of the brains of schizophrenia patients. Archives of General Psychiatry 1996, 53:425-436.
2. Allen P., Laroi F., McGuire P.K., Aleman A. The hallucinating brain: a review of structural and functional neuroimaging studies of hallucinations. Neuroscience and Biobehavioral Reviews 2008, 32:175-191.
3. Brambati S.M., Termine C., Ruffino M., Stella G., Fazio F., Cappa S.F., et al. Regional reductions of gray matter volume in familial dyslexia. Neurology 2004, 63:742-745.
4. Brown W., Eliez S., Menon V., Rumsey J., White C., Reiss A. Preliminary evidence of widespread morphological variations in the brain in dyslexia. Neurology 2001, 56:781-783.
5. Calhoun V.D., Adali T., Pearlson G.D., Pekar J.J. A method for making group inferences from functional MRI data using independent component analysis. Human Brain Mapping 2001, 14:140-151.
6. Demonet J.-F., Thierry G., Cardebat D. Renewal of the neurophysiology of language: functional neuroimaging. Physiological Review 2005, 85:49-95.
7. Deutsch S.I., Burket J.A., Katz E. Does subtle disturbance of neuronal migration contribute to schizophrenia and other neurodevelopmental disorders? Potential genetic mechanisms with possible treatment implications. European Neuropsychopharmacology 2010, 20:281-287.
8. Done D.J., Leinoneen E., Crow T.J., Sacker A. Linguistic performance in children who develop schizophrenia in adult life. Evidence for normal syntactic ability. The British Journal of Psychiatry 1998, 172:130-135.
9. Eckert M. Neuroanatomical markers for dyslexia: a review of dyslexia structural imaging studies. The Neuroscientist 2004, 10:362-371.
10. Fabbro F. Introduction to language and cerebellum. Journal of Neurolinguistics 2000, 13:83-94.
11. First M.B. The DSM series and experience with DSM-IV. Psychopathology 2002, 35:67-71.
12. Francks C., Paracchini S., Smith S.D., Richardson A.J., Scerri T.S., et al. A 77-kb region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. American Journal of Human Genetics 2004, 75:1046-1058.
13. Fuller R., Nopoulos P., Arndt S., O'Leary D., Ho B.C., Andreasen N.C. Longitudinal assessment of premorbid cognitive functioning in patients with schizophrenia through examination of standardized scholastic test performance. The American Journal of Psychiatry 2002, 159:1183-1189.
14. Gabel L.A., Gibson C.J., Gruen J.R., LoTurco J.J. Progress towards a cellular neurobiology of reading disability. Neurobiology of Disease 2010, 38:173-180.
15. Galaburda A.M., Sherman G.F., Rosen G.D., Aboitiz F., Geschwind N. Developmental dyslexia: four consecutive patients with cortical anomalies. Annals of Neurology 1985, 18:222-233.
16. Glahn D.C., Laird A.R., Ellison-Wright I., Thelen S., Robinson J.L., Lancaster J.L., Bullmore E., Fox P.T. Meta-analysis of gray matter anomalies in schizophrenia: application of anatomic likelihood estimation and network analysis. Biological Psychiatry 2008, 64:774-781.
17. Hannula-Jouppi K., Kaminen-Ahola N., Taipale M., Eklund R., Nopola-Hemmi J., et al. The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. PLoS Genetics 2005, 1:e50.
18. Hayes R.L., O'Grady B.M. Do people with schizophrenia comprehend what they read?. Schizophrenia Bulletin 2003, 29:499-507.
19. Hosono S., Faruqi A.F., Dean F.B., Du Y., Sun Z., Wu X., Du J., Kingsmore S.F., Egholm M., Lasken R.S. Unbiased whole-genome amplification directly from clinical samples. Genome Research 2003, 13:954-964.
20. Jagannathan K., Calhoun V.D., Gelernter J., Stevens M.C., Liu J., Bolognani F., Windemuth A., Ruano G., Assaf M., Pearlson G.D. Genetic associations of brain structural networks in schizophrenia: a preliminary study. Biological Psychiatry 2010, 68:657-666.
21. Lai C.S., Gerrelli D., Monaco A.P., Fisher S.E., Copp A.J. FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain 2003, 126:2455-2462.
22. Leonard C.M., Eckert M.A., Lombardino L.J., Oakland T., Kranzler J., Mohr C.M., et al. Anatomical risk factors for phonological dyslexia. Cerebral Cortex 2002, 11:148-157.
23. Leonard C.M., Kuldau J.M., Maron L., Ricciuti N., Mahoney B., Bengtson M., DeBose C. Identical neural risk factors predict cognitive deficit in dyslexia and schizophrenia. Neuropsychology 2008, 22:147-158.
24. Li X., Branch C.A., DeLisi L.E. Language pathway abnormalities in schizophrenia: a review of fMRI and other imaging studies. Current Opinion in Psychiatry 2009, 22:131-139.
25. Liu J., Pearlson G., Windemuth A., Ruano G., Perrone-Bizzero N.I., Calhoun V. Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA. Human Brain Mapping 2009, 30:241-255.
26. Marien P., Engelborghs S., Fabbro F., De Deyn P.P. The lateralized linguistic cerebellum: a review and a new hypothesis. Brain and Language 2001, 79:580-600.
27. Meda S.A., Gelernter J., Gruen J.R., Calhoun V.D., Meng H., Cope N.A., Pearlson G.D. Polymorphism of DCDC2 reveals differences in cortical morphology of healthy individuals - a preliminary voxel based morphometry study. Brain Imaging and Behavior 2007, 2:21-26.
28. Meng H., Smith S.D., Hager K., Held M., Liu J., et al. DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:17053-17058.
29. Paracchini S., Scerri T., Monaco A.P. The genetic lexicon of dyslexia. Annual Review of Genomics and Human Genetics 2007, 8:57-79.
30. Pernet C.R., Poline J.B., Demonet J.F., Rousselet G.A. Brain classification reveals the right cerebellum as the best biomarker of dyslexia. BMC Neuroscience 2010, 10:1-19.
31. Peschansky V.J., Burbridge T.J., Volz A.J., Fiondella C., Wissner Gross Z., Galaburda A.M., Lo Turco J.J., Rosen G.D. The effect of variation in expression of the candidate dyslexia susceptibility gene homolog KIAA0319 on neuronal migration and dendritic morphology in the rat. Cerebral Cortex 2010, 20:884-897.
32. Revheim N., Butler P.D., Schechter I., Jalbrzikowski M., Silipo G., Javitt D.C. Reading impairment and visual processing deficits in schizophrenia. Schizophrenia Research 2006, 87:238-245.
33. Stoodley C.J., Schmahmann J.D. Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. NeuroImage 2009, 44:489-501.
34. Strik W., Dierks T., Hubl D., Horn H. Hallucinations, thought disorders, and the language domain in schizophrenia. Clinical EEG and Neuroscience 2008, 39:91-94.
35. Taipale M., Kaminen N., Nopola-Hemmi J., Haltia T., Myllyluoma B., et al. A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:11553-11558.
36. Zou G.Y. Towards using confidence intervals to compare correlations. Psychological Methods 2007, 12:399-413.