In vitro establishment of ivermectin-resistant Rhipicephalus microplus cell line and the contribution of ABC transporters on the resistance mechanism

Veterinary Parasitology

Volumn 204, Issue 3-4, 2014, Pages 316-322

  Pohl, Paula C ^a,c   Carvalho, Danielle D ^b   Daffre, Sirlei ^c   da Silva Vaz, Itabajara ^a   Masuda, Aoi ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b SD and W Modelagem e Soluções Estratégicas Ltda   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

ATP binding cassette transporter; Ivermectin resistance; Rhipicephalus microplus; Tick cell line

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER B10; ABC TRANSPORTER B7; CYCLOSPORIN A; IVERMECTIN; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG; ACARICIDE;

ACARICIDE RESISTANCE; ANIMAL CELL; ARTICLE; BME26 IVM CELL LINE; CELL SPECIFICITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RESISTANCE; EMBRYO; EMBRYO CELL; EXPOSURE; GENE EXPRESSION; IN VITRO STUDY; INCUBATION TIME; LC 50; MTT ASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHIPICEPHALUS (BOOPHILUS) MICROPLUS; ANIMAL; BOVINE; CATTLE DISEASE; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM; PARASITOLOGY; RHIPICEPHALUS; TICK INFESTATION; VETERINARY;

BOOPHILUS MICROPLUS; IXODIDA; RHIPICEPHALUS;

ACARICIDES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CATTLE; CATTLE DISEASES; CELL LINE; DRUG RESISTANCE; IVERMECTIN; RHIPICEPHALUS; TICK INFESTATIONS;

EID: 84903354653     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2014.05.042     Document Type: Article

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