Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of Nicotiana tabacum suggests detoxification of these insecticides in Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance

Pest Management Science

Volumn 64, Issue 1, 2008, Pages 65-73

  Joußen, Nicole ^a   Heckel, David G ^b   Haas, Matthias ^c   Schuphan, Ingolf ^a   Schmidt, Burkhard ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

^c BAYER CROPSCIENCE AG   (Germany)

Author keywords

Cytochrome P450 CYP6G1; Drosophila melanogaster; Heterologous expression; Insecticide resistance; Tobacco cell cultures

Indexed keywords

CHLORPHENOTANE; CYP6G1 PROTEIN, DROSOPHILA; CYTOCHROME P450; DROSOPHILA PROTEIN; IMIDACLOPRID; IMIDAZOLE DERIVATIVE; INSECTICIDE; NITRO DERIVATIVE; UNCLASSIFIED DRUG;

CONCENTRATION (COMPOSITION); DDT; DETOXIFICATION; ENZYME ACTIVITY; FLY; GENE EXPRESSION; HERB; INSECTICIDE; METABOLISM; PESTICIDE RESISTANCE;

ANIMAL; ARTICLE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DROSOPHILA MELANOGASTER; GENETICS; INSECTICIDE RESISTANCE; METABOLISM; TOBACCO; TRANSGENIC ANIMAL; TRANSGENIC PLANT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DDT; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; IMIDAZOLES; INSECTICIDE RESISTANCE; INSECTICIDES; MOLECULAR STRUCTURE; NITRO COMPOUNDS; PLANTS, GENETICALLY MODIFIED; TOBACCO;

DROSOPHILA MELANOGASTER; HEXAPODA; NICOTIANA TABACUM;

EID: 38349004538     PISSN: 1526498X     EISSN: 15264998     Source Type: Journal    
DOI: 10.1002/ps.1472     Document Type: Article

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