In vitro - In silico - In vivo drug absorption model development based on mechanistic gastrointestinal simulation and artificial neural networks: Nifedipine osmotic release tablets case study

European Journal of Pharmaceutical Sciences

Volumn 62, Issue , 2014, Pages 212-218

  Ilić, Marija ^a   Crossed D Signuriš, Jelena ^a   Kovačević, Ivan ^a   Ibrić, Svetlana ^a   Parojčić, Jelena ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Artificial neural network; Dissolution; Gastrointestinal simulation; In vitro in vivo correlation; Nifedipine

Indexed keywords

NIFEDIPINE; TABLET;

AREA UNDER THE CURVE; ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG SOLUBILITY; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRACT; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MATRIX TABLET; MAXIMUM PLASMA CONCENTRATION; OSMOSIS; PRIORITY JOURNAL; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; BIOLOGICAL MODEL; BLOOD; CHEMISTRY; INTESTINE ABSORPTION; METABOLISM; SOLUBILITY; TABLET;

COMPUTER SIMULATION; GASTROINTESTINAL TRACT; HUMANS; INTESTINAL ABSORPTION; MODELS, BIOLOGICAL; NEURAL NETWORKS (COMPUTER); NIFEDIPINE; SOLUBILITY; TABLETS;

EID: 84903300210     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.05.030     Document Type: Article

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