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Volumn 15, Issue 3, 2002, Pages 279-285

Formulation-dependent food effects demonstrated for nifedipine modified-release preparations marketed in the European Union

Author keywords

Bioavailability; Dose dumping; Food effect; Monolithic erosive tablet; Nifedipine; Osmotic push pull system

Indexed keywords

DRUG THERAPY; FOOD PRODUCTS; OILS AND FATS;

EID: 0036118842     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(02)00008-8     Document Type: Article
Times cited : (70)

References (10)
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    • CPMP Note for Guidance, 1999. CPMP Note for Guidance on Quality of Modified Release Oral and Transdermal Dosage Forms (Section II: Pharmacokinetic and Clinical Evaluation), CPMP/EWP/280/96.
  • 3
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    • Behaviour of single unit and multiple unit dosage forms in the gastrointestinal tract
    • Capsugel Symposium Papers: London Symposium
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    • Davis, S.S.1
  • 4
    • 2042431571 scopus 로고    scopus 로고
    • Food and Drug Administration, 1997. Draft Guidance for Industry: food-effect bioavailability and bioequivalence studies. US Department of Health and Human Services, CDER.
  • 5
    • 0022392154 scopus 로고
    • Food-induced changes in theophylline absorption from controlled-release formulations. Part II: Importance of meal composition and dosing time relative to meal intake in assessing changes in absorption
    • (1985) Clin. Pharmacol. Ther. , vol.38 , pp. 642-647
    • Karim, A.1    Burns, T.2    Janky, D.3    Hurwitz, A.4
  • 8
    • 2042462879 scopus 로고    scopus 로고
    • Schug, B.S., Brendel, E., Chantraine, E., Wolf, D., Martin, W., Schall, R., Blume, H.H., 2001. Dosage form related effect of food on the pharmacokinetics of nifedipine: pronounced lag-time after a high-fat breakfast. Br. J. Clin. Pharmacol. (in press).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.