Adiponectin is better predictor of subclinical atherosclerosis than liver function tests in patients with nonalcoholic fatty liver disease

Journal of the American Society of Hypertension

Volumn 8, Issue 6, 2014, Pages 376-380

  Omelchenko, Elena ^a   Gavish, Dov ^a,b   Shargorodsky, Marina ^a,b  

^a WOLFSON MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Adiponectin; aortic augmentation index; nonalcoholic fatty liver disease; pulse wave velocity

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; BIOLOGICAL MARKER;

ADULT; AGE DISTRIBUTION; ARTERIAL STIFFNESS; ARTICLE; ATHEROSCLEROSIS; AUGMENTATION INDEX; DISEASE ASSOCIATION; FEMALE; HOMEOSTASIS MODEL ASSESSMENT INSULIN RESISTANCE; HUMAN; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; METABOLIC PARAMETERS; NONALCOHOLIC FATTY LIVER; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PULSE WAVE; SYSTOLIC BLOOD PRESSURE; VASCULAR DISEASE; BLOOD; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPLICATION; FOLLOW UP; MIDDLE AGED; PHYSIOLOGY; PROGNOSIS;

ADIPONECTIN; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PROGNOSIS; VASCULAR STIFFNESS;

EID: 84903277937     PISSN: 19331711     EISSN: 18787436     Source Type: Journal    
DOI: 10.1016/j.jash.2014.03.002     Document Type: Article

References (21)

1. E. Bugianesi, A. Gastaldelli, E. Vanni, R. Gambino, M. Cassader, and S. Baldi et al. Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms Diabetologia 48 2005 634 642
2. G. Targher, L. Bertolini, R. Padovani, L. Zenari, G. Zoppini, and G. Falezza Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation Diabetes Care 7 2004 1498 1500
3. A. Brea, D. Mosquera, E. Martin, A. Arizti, J.L. Cordero, and E. Ros Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: a case-control study Arterioscler Thromb Vasc Biol 25 2005 1045 1500
4. G. Targher, L. Bertolini, R. Padovani, S. Rodella, G. Zoppini, and L. Zenari et al. Relations between carotid artery wall thickness and liver histology in subjects with nonalcoholic fatty liver disease Diabetes Care 29 2006 1325 1330
5. F. Ozcelik, C. Yuksel, E. Arslan, S. Genc, B. Omer, and M.A. Serdar Relationship between visceral adipose tissue and, adiponectin, inflammatory markers and thyroid hormones in obese males with hepatosteatosis and insulin resistance Arch Med Res 44 2013 273 280
6. A.T. Turer, J.D. Browning, C.R. Ayers, S.R. Das, A. Khera, and G.L. Vega et al. Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study J Clin Endocrinol Metab 97 2012 E982 E986
7. C. Finelli, and G. Tarantino What is the role of adiponectin in obesity related non-alcoholic fatty liver disease? World J Gastroenterol 19 2013 802 812
8. D. van der Poorten, C.F. Samer, M. Ramezani-Moghadam, S. Coulter, M. Kacevska, and D. Schrijnders et al. Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause? Hepatology 57 2013 2180 2188
9. S.J. Zieman, V. Melenovsky, and D.A. Kass Mechanisms, pathophysiology, and therapy of arterial stiffness Arterioscler Thromb Vasc Biol 25 2005 932 943
10. E.L. Schiffrin Vascular stiffening and arterial compliance Am J Hypertens 17 2004 39 48
11. M.A. Gomez-Marcos, J.I. Recio-Rodríguez, M.C. Patino-Alonso, C. Agudo-Conde, L. Gomez-Sanchez, and E. Rodriguez-Sanchez et al. Yearly evolution of organ damage markers in diabetes or metabolic syndrome: data from the LOD-DIABETES study Cardiovasc Diabetol 10 2011 9
12. S.G. Kim, H.Y. Kim, J.A. Seo, K.W. Lee, H.J. Oh, and N.H. Kim et al. Relationship between serum adiponectin concentration, pulse wave velocity, and nonalcoholic fatty liver disease Europ J Endocrinol 152 2005 225 231
13. D. Joy, V.R. Thava, and B.B. Scott Diagnosis of fatty liver disease: is biopsy necessary? Eur J Gastroenterol Hepatol 15 2003 539 543
14. M. O'Rourke, and J.A. Staessen Clinical application of arterial stiffness definitions and reference values Am J Hypertens 15 2002 426 444
15. G. Tarantino, C. Finelli, A. Colao, D. Capone, M. Tarantino, and E. Grimaldi et al. Are hepatic steatosis and carotid intima media thickness associated in obese patients with normal or slightly elevated gamma-glutamyl-transferase? J Transl Med 10 2012 50
16. T. Claudel, and M. Trauner Adiponectin, bile acids, and burnt-out nonalcoholic steatohepatitis: new light on an old paradox Hepatology 57 2013 2106 2109
17. J.M. Hui, A. Hodge, G.C. Farrell, J.G. Kench, A. Kriketos, and J. George Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 40 2004 46 54
18. C.K. Hui, H.Y. Zhang, N.P. Lee, W. Chan, Y.H. Yueng, and K.W. Leung et al. Serum adiponectin is increased in advancing liver fibrosis and declines with reduction in fibrosis in chronic hepatitis B J Hepatol 47 2007 191 202
19. F. Tacke, T. Wustefeld, R. Horn, T. Luedde, A. Srinivas Rao, and M.P. Manns et al. High adiponectin in chronic liver disease and cholestasis suggests biliary route of adiponectin excretion in vivo J Hepatol 42 2005 666 673
20. P. Sorrentino, G. Tarantino, P. Conca, A. Perrella, M.L. Terracciano, and R. Vecchione et al. Silent non-alcoholic fatty liver disease-a clinical-histological study J Hepatol 41 2004 751 757
21. G. Tarantino, and C. Finelli What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome? World J Gastroenterol 19 2013 3375 3384