-
1
-
-
84903894120
-
Executive summary
-
WHO. Geneva: WHO Press.
-
WHO. Executive summary. In: Global Tuberculosis Control. Geneva: WHO Press, 2011; 1-2.
-
(2011)
Global Tuberculosis Control
, pp. 1-2
-
-
-
2
-
-
79251589638
-
The challenge of new drug discovery for tuberculosis
-
Koul A, Arnoult E, Lounis N et al. The challenge of new drug discovery for tuberculosis. Nature 2011; 469: 483-90.
-
(2011)
Nature
, vol.469
, pp. 483-490
-
-
Koul, A.1
Arnoult, E.2
Lounis, N.3
-
3
-
-
77950849122
-
Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!
-
Amaral L, Boeree MJ, Gillespie SH et al. Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now! Int J Antimicrob Agents 2010; 35: 524-6.
-
(2010)
Int J Antimicrob Agents
, vol.35
, pp. 524-526
-
-
Amaral, L.1
Boeree, M.J.2
Gillespie, S.H.3
-
4
-
-
62949092917
-
New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development
-
van den Boogaard J, Kibiki GS, Kisanga ER et al. New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development. Antimicrob Agents Chemother 2009; 53: 849-62.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 849-862
-
-
Van Den Boogaard, J.1
Kibiki, G.S.2
Kisanga, E.R.3
-
5
-
-
84866488944
-
New treatment options for multidrug-resistant tuberculosis
-
Field SK, Fisher D, Jarand JM et al. New treatment options for multidrug-resistant tuberculosis. Ther Adv Respir Dis 2012; 6: 255-68.
-
(2012)
Ther Adv Respir Dis
, vol.6
, pp. 255-268
-
-
Field, S.K.1
Fisher, D.2
Jarand, J.M.3
-
6
-
-
33846929918
-
Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives
-
Bate AB, Kalin JH, Fooksman EM et al. Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives. Bioorg Med Chem Lett 2007; 17: 1346-8.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 1346-1348
-
-
Bate, A.B.1
Kalin, J.H.2
Fooksman, E.M.3
-
7
-
-
84855829764
-
Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine
-
Garci A, Montaner PG, Abbate E et al. Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine. J Antimicrob Chemother 2012; 67: 473-7.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 473-477
-
-
Garci, A.1
Montaner, P.G.2
Abbate, E.3
-
8
-
-
77953797826
-
In vitro interactions between new antitubercular drug candidates
-
Reddy VM, Einck L, Andries K et al. In vitro interactions between new antitubercular drug candidates. Antimicrob Agents Chemother 2010; 54: 2840-6.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2840-2846
-
-
Reddy, V.M.1
Einck, L.2
Andries, K.3
-
9
-
-
0037416986
-
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis
-
Ordway D, Viveiros M, Leandro C et al. Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother 2003; 47: 917-22.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 917-922
-
-
Ordway, D.1
Viveiros, M.2
Leandro, C.3
-
10
-
-
0030801767
-
The potential management of resistant infections with non-antibiotics
-
Kristiansen JE, Amaral L. The potential management of resistant infections with non-antibiotics. J Antimicrob Chemother 1997; 40: 319-27.
-
(1997)
J Antimicrob Chemother
, vol.40
, pp. 319-327
-
-
Kristiansen, J.E.1
Amaral, L.2
-
11
-
-
33846572768
-
Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei
-
Chan YY, Ong YM, Chua KL. Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. Antimicrob Agents Chemother 2007; 51: 623-30.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 623-630
-
-
Chan, Y.Y.1
Ong, Y.M.2
Chua, K.L.3
-
12
-
-
0030462751
-
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis
-
Amaral L, Kristiansen JE, Abebe LS et al. Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis. J Antimicrob Chemother 1996; 38: 1049-53.
-
(1996)
J Antimicrob Chemother
, vol.38
, pp. 1049-1053
-
-
Amaral, L.1
Kristiansen, J.E.2
Abebe, L.S.3
-
13
-
-
0033839994
-
Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis
-
Bettencourt MV, Bosne-David S, Amaral L. Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis. Int J Antimicrob Agents 2000; 16: 69-71.
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 69-71
-
-
Bettencourt, M.V.1
Bosne-David, S.2
Amaral, L.3
-
14
-
-
0035010729
-
Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy
-
Amaral L, Kristiansen JE, Viveiros M et al. Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy. J Antimicrob Chemother 2001; 47: 505-11.
-
(2001)
J Antimicrob Chemother
, vol.47
, pp. 505-511
-
-
Amaral, L.1
Kristiansen, J.E.2
Viveiros, M.3
-
15
-
-
0035098674
-
Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines
-
Viveiros M, Amaral L. Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines. Int J Antimicrob Agents 2001; 17: 225-8.
-
(2001)
Int J Antimicrob Agents
, vol.17
, pp. 225-228
-
-
Viveiros, M.1
Amaral, L.2
-
16
-
-
0037308580
-
Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus
-
Kaatz GW, Moudgal VV, Seo SM et al. Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus. Antimicrob Agents Chemother 2003; 47: 719-26.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 719-726
-
-
Kaatz, G.W.1
Moudgal, V.V.2
Seo, S.M.3
-
18
-
-
84866004392
-
Thioridazine: an old neuroleptic effective against totally drug resistant tuberculosis
-
Amaral L. Thioridazine: an old neuroleptic effective against totally drug resistant tuberculosis. Acta Méd Port 2012; 25: 118-21.
-
(2012)
Acta Méd Port
, vol.25
, pp. 118-121
-
-
Amaral, L.1
-
19
-
-
33846969173
-
In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis
-
Martins M, Schelz Z, Martins A et al. In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis. Int J Antimicrob Agents 2007; 29: 338-40.
-
(2007)
Int J Antimicrob Agents
, vol.29
, pp. 338-340
-
-
Martins, M.1
Schelz, Z.2
Martins, A.3
-
20
-
-
79958257266
-
Recent progress in biological activities of synthesized phenothiazines
-
Pluta K, Morak-Mlodawska B, Jeleń M. Recent progress in biological activities of synthesized phenothiazines. Eur J Med Chem 2011; 46: 3179-89.
-
(2011)
Eur J Med Chem
, vol.46
, pp. 3179-3189
-
-
Pluta, K.1
Morak-Mlodawska, B.2
Jeleń, M.3
-
21
-
-
84862187466
-
Chemical structure of phenothiazines and their biological activity
-
Jaszczyszyn A, Ga{ogonek}siorowski K, Świa{ogonek}tek P et al. Chemical structure of phenothiazines and their biological activity. Pharmacol Rep 2012; 64: 16-23.
-
(2012)
Pharmacol Rep
, vol.64
, pp. 16-23
-
-
Jaszczyszyn, A.1
Gasiorowski, K.2
Światek, P.3
-
22
-
-
33744957049
-
Steady-state kinetics and inhibitory action of antitubercular phenothiazines on Mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2)
-
Yano T, Li L-S, Weinstein E et al. Steady-state kinetics and inhibitory action of antitubercular phenothiazines on Mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2). J Biol Chem 2006; 281: 11456-63.
-
(2006)
J Biol Chem
, vol.281
, pp. 11456-11463
-
-
Yano, T.1
Li, L.-S.2
Weinstein, E.3
-
23
-
-
84873740882
-
Autoinduction of the metabolism of phenothiazine neuroleptics in a primary culture of human hepatocytes
-
Wójcikowski J, Maurel P, Daniel WA. Autoinduction of the metabolism of phenothiazine neuroleptics in a primary culture of human hepatocytes. Pharmacol Rep 2012; 64: 1578-83.
-
(2012)
Pharmacol Rep
, vol.64
, pp. 1578-1583
-
-
Wójcikowski, J.1
Maurel, P.2
Daniel, W.A.3
-
24
-
-
0344443250
-
Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter
-
Changsen C, Franzblau SG, Palittapongarnpim P. Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter. Antimicrob Agents Chemother 2003; 47: 3682-7.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3682-3687
-
-
Changsen, C.1
Franzblau, S.G.2
Palittapongarnpim, P.3
-
25
-
-
34247859208
-
Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors
-
Madrid PB, Polgar WE, Toll L et al. Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors. Bioorg Med Chem Lett 2007; 17: 3014-7.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 3014-3017
-
-
Madrid, P.B.1
Polgar, W.E.2
Toll, L.3
-
26
-
-
84859428822
-
Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections
-
Amaral L, Viveiros M. Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections. Int J Antimicrob Agents 2012; 39: 376-80.
-
(2012)
Int J Antimicrob Agents
, vol.39
, pp. 376-380
-
-
Amaral, L.1
Viveiros, M.2
-
27
-
-
0035996896
-
Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed
-
Ordway D, Vi M, Leandro C et al. Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus. 2002; 20: 34-43.
-
(2002)
Staphylococcus aureus.
, vol.20
, pp. 34-43
-
-
Ordway, D.1
Vi, M.2
Leandro, C.3
-
28
-
-
0027052626
-
Chlorpromazine: a drug potentially useful for treating mycobacterial infections
-
Crowle AJ, Douvas GS, May MH. Chlorpromazine: a drug potentially useful for treating mycobacterial infections. Chemotherapy 1992; 38: 410-9.
-
(1992)
Chemotherapy
, vol.38
, pp. 410-419
-
-
Crowle, A.J.1
Douvas, G.S.2
May, M.H.3
-
29
-
-
0344004865
-
The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions
-
Daniel WA, Wójcikowski J. The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions. Toxicol Appl Pharmacol 1999; 158: 115-24.
-
(1999)
Toxicol Appl Pharmacol
, vol.158
, pp. 115-124
-
-
Daniel, W.A.1
Wójcikowski, J.2
-
30
-
-
77955889510
-
Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB
-
Amaral L, Martins A, Molnar J et al. Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB. In Vivo 2010; 24: 409-24.
-
(2010)
In Vivo
, vol.24
, pp. 409-424
-
-
Amaral, L.1
Martins, A.2
Molnar, J.3
-
31
-
-
40749110626
-
Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M. tuberculosis by non-killing macrophages
-
Martins M, Viveiros M, Amaral L. Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M. tuberculosis by non-killing macrophages. In Vivo 2008; 22: 69-75.
-
(2008)
In Vivo
, vol.22
, pp. 69-75
-
-
Martins, M.1
Viveiros, M.2
Amaral, L.3
-
32
-
-
80052050200
-
Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages
-
Welin A, Raffetseder J, Eklund D et al. Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages. J Innate Immun 2011; 3: 508-18.
-
(2011)
J Innate Immun
, vol.3
, pp. 508-518
-
-
Welin, A.1
Raffetseder, J.2
Eklund, D.3
-
33
-
-
0035284908
-
Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages
-
Malik ZA, Iyer SS, Kusner DJ et al. Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages. J Immunol 2001; 166: 3392-401.
-
(2001)
J Immunol
, vol.166
, pp. 3392-3401
-
-
Malik, Z.A.1
Iyer, S.S.2
Kusner, D.J.3
|