Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia

Blood

Volumn 123, Issue 20, 2014, Pages 3116-3127

  Williams, Mark T S ^a   Yousafzai, Yasar ^a,b   Cox, Charlotte ^c   Blair, Allison ^c,d   Carmody, Ruaidhrí ^a   Sai, Shuji ^e   Chapman, Karen E ^e   McAndrew, Rachel ^f   Thomas, Angela ^f   Spence, Alison ^g   Gibson, Brenda ^g   Graham, Gerard J ^a   Halsey, Christina ^a,g  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b KHYBER MEDICAL UNIVERSITY   (Pakistan)

^c NHS BLOOD AND TRANSPLANT   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^g ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CXCR3; FR 180204; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 15 RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; P SELECTIN GLYCOPROTEIN LIGAND 1; PHOSPHATIDYLINOSITOL 3 KINASE; STAT5 INHIBITOR; STAT5 PROTEIN; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; B CELL LEUKEMIA; BIOLOGICAL ACTIVITY; BLAST CELL; CANCER CELL LINE; CANCER GROWTH; CANCER RECURRENCE; CANCER TISSUE; CELL LEVEL; CENTRAL NERVOUS SYSTEM TUMOR; CEREBROSPINAL FLUID; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; INTRACELLULAR SIGNALING; LEUKEMOGENESIS; LYMPHOCYTE HOMING; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; TUMOR XENOGRAFT; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-15; MEMBRANE GLYCOPROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, CXCR3; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84903178881     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-05-499970     Document Type: Article

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