-
1
-
-
0038638396
-
Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Campath-1H)
-
Kirk AD, Hale DA, Mannon RB, et al. Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Campath-1H). Transplantation 2003; 76: 120-129.
-
(2003)
Transplantation
, vol.76
, pp. 120-129
-
-
Kirk, A.D.1
Hale, D.A.2
Mannon, R.B.3
-
2
-
-
33645795235
-
Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it
-
Neujahr DC, Chen CQ, Huang X, et al. Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it. J Immunol 2006; 176: 4632-4639.
-
(2006)
J Immunol
, vol.176
, pp. 4632-4639
-
-
Neujahr, D.C.1
Chen, C.Q.2
Huang, X.3
-
3
-
-
44849105008
-
Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection
-
Moxham VF, Karegli J, Phillips RE, et al. Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol 2008; 180: 3910-3918.
-
(2008)
J Immunol
, vol.180
, pp. 3910-3918
-
-
Moxham, V.F.1
Karegli, J.2
Phillips, R.E.3
-
4
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
-
Schluns KS, Kieper WC, Jameson SC, Lefrancois L., Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000; 1: 426-432.
-
(2000)
Nat Immunol
, vol.1
, pp. 426-432
-
-
Schluns, K.S.1
Kieper, W.C.2
Jameson, S.C.3
Lefrancois, L.4
-
5
-
-
0035902513
-
IL-7 is critical for homeostatic proliferation and survival of naive T cells
-
Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A 2001; 98: 8732-8737.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8732-8737
-
-
Tan, J.T.1
Dudl, E.2
Leroy, E.3
-
6
-
-
17844370566
-
A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells
-
Bourgeois C, Kassiotis G, Stockinger B., A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells. J Immunol 2005; 174: 5316-5323.
-
(2005)
J Immunol
, vol.174
, pp. 5316-5323
-
-
Bourgeois, C.1
Kassiotis, G.2
Stockinger, B.3
-
7
-
-
0024332461
-
Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo
-
Rocha B, Dautigny N, Pereira P., Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo. Eur J Immunol 1989; 19: 905-911.
-
(1989)
Eur J Immunol
, vol.19
, pp. 905-911
-
-
Rocha, B.1
Dautigny, N.2
Pereira, P.3
-
8
-
-
0034698828
-
Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells
-
Cho BK, Rao VP, Ge Q, Eisen HN, Chen JZ., Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J Exp Med 2000; 192: 549-556.
-
(2000)
J Exp Med
, vol.192
, pp. 549-556
-
-
Cho, B.K.1
Rao, V.P.2
Ge, Q.3
Eisen, H.N.4
Chen, J.Z.5
-
9
-
-
0034698931
-
Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
-
Goldrath AW, Bogatzki LY, Bevan MJ., Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J Exp Med 2000; 192: 557-564.
-
(2000)
J Exp Med
, vol.192
, pp. 557-564
-
-
Goldrath, A.W.1
Bogatzki, L.Y.2
Bevan, M.J.3
-
10
-
-
20044380331
-
Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion
-
Pearl JP, Parris J, Hale DA, et al. Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. Am J Transplant 2005; 5: 465-474.
-
(2005)
Am J Transplant
, vol.5
, pp. 465-474
-
-
Pearl, J.P.1
Parris, J.2
Hale, D.A.3
-
11
-
-
11144355749
-
Homeostatic proliferation is a barrier to transplantation tolerance
-
Wu ZH, Bensinger SJ, Zhang JD, et al. Homeostatic proliferation is a barrier to transplantation tolerance. Nat Med 2004; 10: 87-92.
-
(2004)
Nat Med
, vol.10
, pp. 87-92
-
-
Wu, Z.H.1
Bensinger, S.J.2
Zhang, J.D.3
-
12
-
-
20444373376
-
Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells
-
Battaglia M, Stabilini A, Roncarolo MG., Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells. Blood 2005; 105: 4743-4748.
-
(2005)
Blood
, vol.105
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
13
-
-
38049177784
-
Differential impact of mammalian target of rapamycin inhibition on CD4(+)CD25(+)Foxp3(+) regulatory T cells compared with conventional CD4(+) T cells
-
Zeiser R, Leveson-Gower DB, Zambricki EA, et al. Differential impact of mammalian target of rapamycin inhibition on CD4(+)CD25(+)Foxp3(+) regulatory T cells compared with conventional CD4(+) T cells. Blood 2008; 111: 453-462.
-
(2008)
Blood
, vol.111
, pp. 453-462
-
-
Zeiser, R.1
Leveson-Gower, D.B.2
Zambricki, E.A.3
-
14
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693-1700.
-
(2006)
J Exp Med
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
-
15
-
-
0027443753
-
Expression and function of the interleukin-7 receptor in murine lymphocytes
-
Sudo T, Nishikawa S, Ohno N, et al. Expression and function of the interleukin-7 receptor in murine lymphocytes. Proc Natl Acad Sci U S A 1993; 90: 9125-9129.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9125-9129
-
-
Sudo, T.1
Nishikawa, S.2
Ohno, N.3
-
16
-
-
0033559501
-
Elimination of the immunogenicity of therapeutic antibodies
-
Gilliland LK, Walsh LA, Frewin MR, et al. Elimination of the immunogenicity of therapeutic antibodies. J Immunol 1999; 162: 3663-3671.
-
(1999)
J Immunol
, vol.162
, pp. 3663-3671
-
-
Gilliland, L.K.1
Walsh, L.A.2
Frewin, M.R.3
-
17
-
-
33644626883
-
Campath: From concept to clinic
-
Waldmann H, Hale G., Campath: From concept to clinic. Philos T Roy Soc B 2005; 360: 1707-1711.
-
(2005)
Philos T Roy Soc B
, vol.360
, pp. 1707-1711
-
-
Waldmann, H.1
Hale, G.2
-
18
-
-
0024553650
-
Monoclonal-antibodies recognizing transforming growth factor-beta - Bioactivity neutralization and transforming growth-factor beta-2 affinity purification
-
Dasch JR, Pace DR, Waegell W, Inenaga D, Ellingsworth L., Monoclonal-antibodies recognizing transforming growth factor-beta-Bioactivity neutralization and transforming growth-factor beta-2 affinity purification. J Immunol 1989; 142: 1536-1541.
-
(1989)
J Immunol
, vol.142
, pp. 1536-1541
-
-
Dasch, J.R.1
Pace, D.R.2
Waegell, W.3
Inenaga, D.4
Ellingsworth, L.5
-
19
-
-
0029918208
-
T cell suppression in transplantation tolerance through linked recognition
-
Davies JD, Leong LYW, Mellor A, Cobbold SP, Waldmann H., T cell suppression in transplantation tolerance through linked recognition. J Immunol 1996; 156: 3602-3607.
-
(1996)
J Immunol
, vol.156
, pp. 3602-3607
-
-
Davies, J.D.1
Leong, L.Y.W.2
Mellor, A.3
Cobbold, S.P.4
Waldmann, H.5
-
20
-
-
84903146533
-
-
FlowJO TSI, Ashland Oregon, USA Available at:. Accessed January 20, 2011
-
FlowJO TSI, Ashland Oregon, USA. Proliferation Tutorial. Available at: http://wwwflowjocom/home/tutorials/proliferationhtml. Accessed January 20, 2011.
-
Proliferation Tutorial
-
-
-
21
-
-
0348223787
-
Conversion of peripheral CD4(+)CD25(-) naive T cells to CD4(+)CD25(+) regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen WJ, Jin WW, Hardegen N, et al. Conversion of peripheral CD4(+)CD25(-) naive T cells to CD4(+)CD25(+) regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003; 198: 1875-1886.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.J.1
Jin, W.W.2
Hardegen, N.3
-
22
-
-
84855608212
-
Immune profile of pediatric renal transplant recipients following alemtuzumab induction
-
De Serres SA, Mfarrej BG, Magee CN, et al. Immune profile of pediatric renal transplant recipients following alemtuzumab induction. J Am Soc Nephrol 2012; 23: 174-182.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 174-182
-
-
De Serres, S.A.1
Mfarrej, B.G.2
Magee, C.N.3
-
23
-
-
27944439639
-
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
-
Cox AL, Thompson SAJ, Jones JL, et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005; 35: 3332-3342.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3332-3342
-
-
Cox, A.L.1
Thompson, S.A.J.2
Jones, J.L.3
-
24
-
-
69949120991
-
Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model
-
Hu YP, Turner MJ, Shields J, et al. Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model. Immunology 2009; 128: 260-270.
-
(2009)
Immunology
, vol.128
, pp. 260-270
-
-
Hu, Y.P.1
Turner, M.J.2
Shields, J.3
-
25
-
-
3042800728
-
Donor-specific transplantation tolerance: The paradoxical behavior of CD4(+)CD25(+) T cells
-
Graca L, Le Moine A, Lin CY, Fairchild PJ, Cobbold SP, Waldmann H., Donor-specific transplantation tolerance: The paradoxical behavior of CD4(+)CD25(+) T cells. Proc Natl Acad Sci U S A 2004; 101: 10122-10126.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10122-10126
-
-
Graca, L.1
Le Moine, A.2
Lin, C.Y.3
Fairchild, P.J.4
Cobbold, S.P.5
Waldmann, H.6
-
26
-
-
84864510487
-
IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells
-
Penaranda C, Kuswanto W, Hofmann J, et al. IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A 2012; 109: 12668-12673.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12668-12673
-
-
Penaranda, C.1
Kuswanto, W.2
Hofmann, J.3
-
27
-
-
33751191378
-
Neutralizing IL-7 promotes long-term allograft survival induced by CD40/CD40L costimulatory blockade
-
Wang Y, Dai H, Liu Z, Cheng X, Tellides G, Dai Z., Neutralizing IL-7 promotes long-term allograft survival induced by CD40/CD40L costimulatory blockade. Am J Transplant 2006; 6: 2851-2860.
-
(2006)
Am J Transplant
, vol.6
, pp. 2851-2860
-
-
Wang, Y.1
Dai, H.2
Liu, Z.3
Cheng, X.4
Tellides, G.5
Dai, Z.6
-
28
-
-
10844292763
-
Immunosuppressive drugs for kidney transplantation
-
Halloran PF., Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004; 351: 2715-2729.
-
(2004)
N Engl J Med
, vol.351
, pp. 2715-2729
-
-
Halloran, P.F.1
-
29
-
-
80555129271
-
Sustained suppression by Foxp3(+) regulatory T cells is vital for infectious transplantation tolerance
-
Kendal AR, Chen Y, Regateiro FS, et al. Sustained suppression by Foxp3(+) regulatory T cells is vital for infectious transplantation tolerance. J Exp Med 2011; 208: 2043-2053.
-
(2011)
J Exp Med
, vol.208
, pp. 2043-2053
-
-
Kendal, A.R.1
Chen, Y.2
Regateiro, F.S.3
|