Stabilisation of amorphous ibuprofen in Upsalite, a mesoporous magnesium carbonate, as an approach to increasing the aqueous solubility of poorly soluble drugs

International Journal of Pharmaceutics

Volumn 472, Issue 1-2, 2014, Pages 185-191

  Zhang, Peng ^a   Forsgren, Johan ^a   Strømme, Maria ^a,b  

^a Department of Engineering Sciences   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Bioavailability; Ibuprofen; Magnesium carbonate; Mesoporous; Poorly soluble drug

Indexed keywords

IBUPROFEN; MAGNESIUM CARBONATE; MAGNESIUM; NONSTEROID ANTIINFLAMMATORY AGENT;

AQUEOUS SOLUTION; ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; HUMIDITY; INFRARED SPECTROSCOPY; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; THERMOGRAVIMETRY; X RAY POWDER DIFFRACTION; CHEMISTRY; DRUG STABILITY; MEDICINAL CHEMISTRY; POROSITY; SOLUBILITY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG LIBERATION; DRUG STABILITY; IBUPROFEN; MAGNESIUM; POROSITY; SOLUBILITY;

EID: 84903173189     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.06.025     Document Type: Article

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