Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice

Blood

Volumn 123, Issue 21, 2014, Pages 3344-3353

  Morioka, Yoko ^a   Casari, Caterina ^b   Wohner, Nikolett ^b   Cho, Sungyun ^c   Kurata, Sachiko ^a   Kitano, Ayumi ^a   Christophe, Olivier D ^b   Lenting, Peter J ^b   Li, Renhao ^c   Denis, Cécile V ^b   Prévost, Nicolas ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISINTEGRIN; HISTAMINE; METALLOPROTEINASE; POLYMER; THROMBOSPONDIN 1; VON WILLEBRAND FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; KIDNEY DYSFUNCTION; MICROVASCULATURE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PLASMAPHERESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SPLENOMEGALY; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOTIC THROMBOCYTOPENIC PURPURA;

AMINO ACID SEQUENCE; ANIMALS; DISULFIDES; HEK293 CELLS; HUMANS; HYDROLYSIS; KIDNEY; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE HYDROLASES; PROTEIN STRUCTURE, TERTIARY; PURPURA, THROMBOTIC THROMBOCYTOPENIC; VON WILLEBRAND FACTOR;

EID: 84903164832     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-10-531392     Document Type: Article

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