Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 7, 2014, Pages 3666-3678

  Trenholme, Katharine ^a,b   Marek, Linda ^c   Duffy, Sandra ^d   Pradel, Gabriele ^e   Fisher, Gillian ^d   Hansen, Finn K ^c   Skinner Adams, Tina S ^d   Butterworth, Alice ^a,b   Ngwa, Che Julius ^e   Moecking, Jonas ^e   Goodman, Christopher D ^f   McFadden, Geoffrey I ^f   Sumanadasa, Subathdrage D M ^d   Fairlie, David P ^b   Avery, Vicky M ^d   Kurz, Thomas ^c   Andrews, Katherine T ^d  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d GRIFFITH UNIVERSITY   (Australia)

^e RWTH AACHEN UNIVERSITY   (Germany)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HISTONE DEACETYLASE; LYSINE; NONHISTONE PROTEIN; TRICHOSTATIN A; VORINOSTAT; ADENOSINE TRIPHOSPHATE; ANTIMALARIAL AGENT; HISTONE DEACETYLASE INHIBITOR; MOLECULAR LIBRARY;

ACETYLATION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; GAMETOCYTE; GAMETOCYTOCIDAL ACTIVITY; GENE EXPRESSION; LIFE CYCLE STAGE; NONHUMAN; PLASMODIUM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN PROCESSING; SEXUAL DEVELOPMENT; TROPHOZOITE; ANIMAL; DRUG EFFECTS; FLAGELLUM; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR LIBRARY; PLASMODIUM BERGHEI;

ACETYLATION; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIMALARIALS; FLAGELLA; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; LYSINE; PLASMODIUM; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SMALL MOLECULE LIBRARIES;

EID: 84903148468     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02721-13     Document Type: Article

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