-
1
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase iii study: 5-year analysis of the eortc-ncic trial
-
Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009;10:459-66
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
2
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012;12:265-77
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
3
-
-
78650801857
-
Sipuleucel-T: In metastatic castration-resistant prostate cancer
-
Plosker GL. Sipuleucel-T: In metastatic castration-resistant prostate cancer. Drugs 2011;71(1):101-8
-
(2011)
Drugs
, vol.71
, Issue.1
, pp. 101-108
-
-
Plosker, G.L.1
-
4
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
Ransohoff RM, Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol 2012;12:623-35
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
5
-
-
84888317089
-
Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma
-
Ochs K, Sahm F, Opitz CA, et al. Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma. J Neuroimmunol 2013;265:106-16
-
(2013)
J Neuroimmunol
, vol.265
, pp. 106-116
-
-
Ochs, K.1
Sahm, F.2
Opitz, C.A.3
-
6
-
-
84880757177
-
Deciphering and reversing tumor immune suppression
-
Motz GT, Coukos G. Deciphering and reversing tumor immune suppression. Immunity 2013;39:61-73
-
(2013)
Immunity
, vol.39
, pp. 61-73
-
-
Motz, G.T.1
Coukos, G.2
-
7
-
-
84883554099
-
Active immunotherapy using dendritic cells in the treatment of glioblastoma multiforme
-
Bregy A, Wong TM, Shah AH, et al. Active immunotherapy using dendritic cells in the treatment of glioblastoma multiforme. Cancer Treat Rev 2013;39:891-907
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 891-907
-
-
Bregy, A.1
Wong, T.M.2
Shah, A.H.3
-
8
-
-
84870985481
-
Integration of autologous dendritic cell-based immunotherapyin the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 phase I/II trial
-
Ardon H, Van Gool SW, Verschuere T,et al. Integration of autologous dendritic cell-based immunotherapyin the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 phase I/II trial. Cancer Immunol Immunother 2012;61:2033-44
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 2033-2044
-
-
Ardon, H.1
Van Gool, S.W.2
Verschuere, T.3
-
9
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
DOI 10.1016/j.ccr.2006.02.019, PII S1535610806000560
-
Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006;9:157-73 (Pubitemid 43357943
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
Misra, A.7
Nigro, J.M.8
Colman, H.9
Soroceanu, L.10
Williams, P.M.11
Modrusan, Z.12
Feuerstein, B.G.13
Aldape, K.14
-
10
-
-
37549007198
-
Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis
-
Shirahata M, Iwao-Koizumi K, Saito S,et al. Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis. Clin Cancer Res 2007;13:7341-56
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7341-7356
-
-
Shirahata, M.1
Iwao-Koizumi, K.2
Saito, S.3
-
11
-
-
79952711945
-
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy
-
Prins RM, Soto H, Konkankit V, et al. Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy. Clin Cancer Res 2011;17:1603-15
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1603-1615
-
-
Prins, R.M.1
Soto, H.2
Konkankit, V.3
-
12
-
-
9144247794
-
Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study
-
DOI 10.1038/sj.bjc.6602195
-
Rutkowski S, De Vleeschouwer S,Kaempgen E, et al. Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study. Br J Cancer 2004;91: 1656-62 (Pubitemid 39546137
-
(2004)
British Journal of Cancer
, vol.91
, Issue.9
, pp. 1656-1662
-
-
Rutkowski, S.1
De Vleeschouwer, S.2
Kaempgen, E.3
Wolff, J.E.A.4
Kuhl, J.5
Demaerel, P.6
Warmuth-Metz, M.7
Flamen, P.8
Van Calenbergh, F.9
Plets, C.10
Sorensen, N.11
Opitz, A.12
Van Gool, S.W.13
-
13
-
-
49649113879
-
Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme
-
De Vleeschouwer S, Fieuws S, Rutkowski S,et al. Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme. Clin Cancer Res 2008;14:3098-104
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3098-3104
-
-
De Vleeschouwer, S.1
Fieuws, S.2
Rutkowski, S.3
-
14
-
-
54549108740
-
Comprehensive genomic characterization Defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization Defines human glioblastoma genes and core pathways. Nature 2008; 455(7216):1061-8
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
15
-
-
84894573670
-
Paediatric and adult glioblastoma: Multiform (epi)genomic culprits emerge
-
Sturm D, Bender S, Jones DTW, et al. Paediatric and adult glioblastoma: Multiform (epi)genomic culprits emerge. Nat Rev Cancer 2014;14:92-107
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 92-107
-
-
Sturm, D.1
Bender, S.2
Jones, D.T.W.3
-
16
-
-
0242329784
-
Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: Results of a clinical phase I/II trial
-
DOI 10.1038/sj.bjc.6601268
-
Yamanaka R, Abe T, Yajima N, et al. Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: Results of a clinical phase I/II trial. Br J Cancer 2003;89:1172-9 (Pubitemid 37363398
-
(2003)
British Journal of Cancer
, vol.89
, Issue.7
, pp. 1172-1179
-
-
Yamanaka, R.1
Abe, T.2
Yajima, N.3
Tsuchiya, N.4
Homma, J.5
Kobayashi, T.6
Narita, M.7
Takahashi, M.8
Tanaka, R.9
-
17
-
-
70350236627
-
An epidermal growth factor receptor variant III-Targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
-
Sampson JH, Archer GE, Mitchell DA,et al. An epidermal growth factor receptor variant III-Targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme. Mol Cancer Ther 2009;8: 2773-9
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2773-2779
-
-
Sampson, J.H.1
Archer, G.E.2
Mitchell, D.A.3
-
18
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE,et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol 2010;28:4722-9
-
(2010)
J Clin Oncol
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
19
-
-
79951978155
-
Induction of CD8+ T-cell responses against novel glioma-Associated antigen peptides and clinical activity by vaccinations with {alpha}-Type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma
-
Okada H, Kalinski P, Ueda R, et al. Induction of CD8+ T-cell responses against novel glioma-Associated antigen peptides and clinical activity by vaccinations with {alpha}-Type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma. J Clin Oncol 2011;29:330-6
-
(2011)
J Clin Oncol
, vol.29
, pp. 330-336
-
-
Okada, H.1
Kalinski, P.2
Ueda, R.3
-
20
-
-
84855597498
-
Clinical application of a dendritic cell vaccine raised against heat- shocked glioblastoma
-
Jie X, Hua L, Jiang W, et al. Clinical application of a dendritic cell vaccine raised against heat- shocked glioblastoma. Cell Biochem Biophys 2012;62:91-9
-
(2012)
Cell Biochem Biophys
, vol.62
, pp. 91-99
-
-
Jie, X.1
Hua, L.2
Jiang, W.3
-
21
-
-
84872498982
-
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
-
Phuphanich S, Wheeler CJ, Rudnick JD,et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother 2013;62:125-35
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 125-135
-
-
Phuphanich, S.1
Wheeler, C.J.2
Rudnick, J.D.3
-
22
-
-
84871546020
-
A-Type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: A phase I clinical trial
-
Akiyama Y, Oshita C, Kume A, et al. a-Type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: A phase I clinical trial. BMC Cancer 2012;12:623
-
(2012)
BMC Cancer
, vol.12
, pp. 623
-
-
Akiyama, Y.1
Oshita, C.2
Kume, A.3
-
23
-
-
81055130102
-
Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-Thymidine ([18F]FLT) PET imaging
-
Aarntzen EH, Srinivas M, De Wilt JH,et al. Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy- Thymidine ([18F]FLT) PET imaging. Proc Natl Acad Sci USA 2011;108:18396-9
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18396-18399
-
-
Aarntzen, E.H.1
Srinivas, M.2
De Wilt, J.H.3
-
25
-
-
48649096955
-
Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients
-
Wheeler CJ, Black KL, Liu G, et al. Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients. Cancer Res 2008;68: 5955-64
-
(2008)
Cancer Res
, vol.68
, pp. 5955-5964
-
-
Wheeler, C.J.1
Black, K.L.2
Liu, G.3
-
26
-
-
23044479028
-
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
-
DOI 10.1158/1078-0432.CCR-05-0464
-
Liau LM, Prins RM, Kiertscher SM, et al. Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res 2005;11:5515-25 (Pubitemid 41060828
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.15
, pp. 5515-5525
-
-
Liau, L.M.1
Prins, R.M.2
Kiertscher, S.M.3
Odesa, S.K.4
Kremen, T.J.5
Giovannone, A.J.6
Lin, J.-W.7
Chute, D.J.8
Mischet, P.S.9
Cloughesy, T.F.10
Roth, M.D.11
-
27
-
-
39149097490
-
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study
-
DOI 10.1215/15228517-2007-046
-
Heimberger AB, Sun W, Hussain SF, et al. Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study. Neuro Oncol 2008;10:98-103 (Pubitemid 351250906
-
(2008)
Neuro-Oncology
, vol.10
, Issue.1
, pp. 98-103
-
-
Heimberger, A.B.1
Sun, W.2
Hussain, S.F.3
Dey, M.4
Crutcher, L.5
Aldape, K.6
Gilbert, M.7
Hassenbusch, S.J.8
Sawaya, R.9
Schmittling, B.10
Archer, G.E.11
Mitchell, D.A.12
Bigner, D.D.13
Sampson, J.H.14
-
28
-
-
79960735609
-
A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma
-
Chang CN, Huang YC, Yang DM, et al. A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma. J Clin Neurosci 2011;18:1048-54
-
(2011)
J Clin Neurosci
, vol.18
, pp. 1048-1054
-
-
Chang, C.N.1
Huang, Y.C.2
Yang, D.M.3
-
29
-
-
0035988623
-
Immune modulation by ionizing radiation and its implications for cancer immunotherapy
-
DOI 10.2174/1381612023394089
-
Friedman EJ. Immune modulation by ionizing radiation and its implications for cancer immunotherapy. Curr Pharm Des 2002;8:1765-80 (Pubitemid 34846202
-
(2002)
Current Pharmaceutical Design
, vol.8
, Issue.19
, pp. 1765-1780
-
-
Friedman, E.J.1
-
30
-
-
24944552128
-
Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-Tumor cell fusion vaccines
-
Kjaergaard J, Wang LX, Kuriyama H, et al. Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-Tumor cell fusion vaccines. J Neurosurg 2005;103:156-64 (Pubitemid 43193947
-
(2005)
Journal of Neurosurgery
, vol.103
, Issue.1
, pp. 156-164
-
-
Kjaergaard, J.1
Wang, L.-X.2
Kuriyama, H.3
Shu, S.4
Plautz, G.E.5
-
31
-
-
84870741733
-
-
Available from
-
Cancer research UK. Available from: Www.cancerresearchuk.org/cancer-help/ trials/a-Trial-of-A-vaccine-called-dcvax-l-forglioblastoma-multiforme.
-
Cancer research UK
-
-
|