Wild celery (Smyrnium olusatrum L.) oil and isofuranodiene induce apoptosis in human colon carcinoma cells

Fitoterapia

Volumn 97, Issue , 2014, Pages 133-141

  Quassinti, Luana ^a   Maggi, Filippo ^a   Barboni, Luciano ^a   Ricciutelli, Massimo ^a   Cortese, Manuela ^a   Papa, Fabrizio ^a   Garulli, Chiara ^a   Kalogris, Cristina ^a   Vittori, Sauro ^a   Bramucci, Massimo ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Apoptosis; Colon carcinoma cells; Essential oil; Isofuranodiene; Smyrnium olusatrum

Indexed keywords

3 CARENE; ALPHA PHELLANDRENE; ALPHA THUJENE; ANTINEOPLASTIC AGENT; BETA PHELLANDRENE; BETA PINENE; BICYCLOGERMACRENE; BOURBONENE; BUTYLCRESOL; CARYOPHYLLENE; COPAENE; DOCOSANE; ESSENTIAL OIL; GERANYL ACETATE; GERMACRENE D; GLECHOMAFURAN; HENICOSANE; HUMULENE; LIMONENE; LINALOOL; MYRCENE; OCIMENE; PARA CYMENE; PENTACOSANE; PINENE; SABINENE; TERPINENE; TETRACOSANE; TRICOSANE; UNCLASSIFIED DRUG; UNINDEXED DRUG; FURAN DERIVATIVE; ISOFURANODIENE; PLANT EXTRACT;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CELERY; CHEMICAL COMPOSITION; COLON CARCINOMA; CONTROLLED STUDY; DRUG ISOLATION; ENZYME ACTIVITY; FLOWER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MTT ASSAY; PRIORITY JOURNAL; SMYRNIUM OLUSATRUM; APIACEAE; CARCINOMA; CHEMISTRY; COLONIC NEOPLASMS; DNA FRAGMENTATION; DRUG EFFECTS; DRUG SCREENING; FLUORESCENCE MICROSCOPY; HCT116 CELL LINE; ISOLATION AND PURIFICATION; PHYTOTHERAPY;

APIACEAE; APOPTOSIS; CARCINOMA; COLONIC NEOPLASMS; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; FURANS; HCT116 CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; OILS, VOLATILE; PHYTOTHERAPY; PLANT EXTRACTS;

EID: 84903139184     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.06.004     Document Type: Article

References (24)

1. F. Maggi, L. Barboni, F. Papa, G. Caprioli, M. Ricciutelli, and G. Sagratini et al. A forgotten vegetable (Smyrnium olusatrum L., Apiaceae) as a rich source of isofuranodiene Food Chem 135 2012 2852 2862
2. J. Lu, Y. Dang, M. Huang, W. Xu, X. Chen, and Y. Wang Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - a review J Ethnopharmacol 143 2012 406 411
3. W.S. Xu, Y.Y. Dang, J.J. Guo, G.S. Wu, J.J. Lu, and X.P. Chen et al. Furanodiene induces endoplasmic reticulum stress and presents antiproliferative activities in lung cancer cells Evid Based Complement Alternat Med 2012 10.1155/2012/426521 [art. no. 426521]
4. Z. Zhong, Y. Dang, X. Yuan, W. Guo, Y. Li, and W. Tan et al. Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo Cell Physiol Biochem 30 2012 778 790
5. S. Pignatti Flora d'Italia vol. 2 1982 Edagricole Bologna 187
6. M. Gavagnin, E. Mollo, F. Castelluccio, A. Crispino, and G. Cimino Sesquiterpene metabolites of the antarctic gorgonian Dasystenella acanthine J Nat Prod 66 2003 1517 1519 (Pubitemid 37490409)
7. J. Yan, G. Chen, S. Tong, Y. Feng, L. Sheng, and J. Lou Preparative isolation and purification of germacrone and curdione from the essential oil of the rhizomes of Curcuma wenyujin by high-speed counter-current chromatography J Chromatogr A 1070 2005 207 210 (Pubitemid 40417785)
8. R.P. Adams Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry 2007 Allured Publishing Corporation Carol Stream, Illinois
9. NIST 08 Mass Spectral Library (NIST/EPA/NIH) 2008 National Institute of Standards and Technology Gaithersburg, USA
10. U. Mölleken, V. Sinnwell, and K.-H. Kubeczka Essential oil composition of Smyrnium olusatrum Phytochemistry 49 1998 1709 1714 (Pubitemid 28559565)
11. U. Mölleken, V. Sinnwell, and K.-H. Kubeczka The essential oil composition of fruits from Smyrnium perfoliatum Phytochemistry 47 1998 1079 1083 (Pubitemid 28173304)
12. W.N. Setzer Ab initio analysis of the Cope rearrangement of germacrane sesquiterpenoids J Mol Model 14 2008 335 342
13. L. Quassinti, G. Lupidi, F. Maggi, G. Sagratini, F. Papa, and S. Vittori et al. Antioxidant and antiproliferative activity of Hypericum hircinum L. subsp. majus (Aiton) N. Robson essential oil Nat Prod Res 27 2013 862 868
14. T.G. Cotter, and S.G. Martin Techniques in Apoptosis. A Use's Guide 1996 Portland Press Ltd. London 7 9
15. C. Le Bel, H. Ischiropoulos, and S.C. Bondy Evaluation of the probe 2′',7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress Chem Res Toxicol 5 1992 227 231
16. J. Kawabata, Y. Fukushi, S. Tahara, and J. Mizutani Isolation and structural elucidation of four sesquiterpenes from Chloranthus japonicus (Chloranthaceae) Agric Biol Chem 49 1985 1479 1486
17. R.E. Randall Smyrnium olusatrum L J Ecol 91 2003 325 340
18. F. Papaioannou, A. Koutsaviti, and O. Tzakou Volatile constituents of different parts of Smyrnium olusatrum from Greece Nat Prod Commun 5 2010 1 2
19. L. Quassinti, M. Bramucci, G. Lupidi, L. Barboni, M. Ricciutelli, and G. Sagratini et al. In vitro biological activity of essential oils and isolated furanosesquiterpenes from the neglected vegetable Smyrnium olusatrum L. (Apiaceae) Food Chem 138 2013 808 813
20. Q. Kong, F. Sun, and X. Chen Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation Cell J 15 2013 160 165
21. A.G. Porter, and R.U. JaÈnicke Emerging roles of caspase-3 in apoptosis Cell Death Differ 6 1996 99 104 (Pubitemid 29082297)
22. E. Ma, X. Wang, Y. Li, X. Sun, W. Tai, and T. Li et al. Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway Cancer Lett 271 2008 158 166
23. Z. Zhong, X. Chen, W. Tan, Z. Xu, K. Zhou, and T. Wu et al. Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis Eur J Pharmacol 667 2011 50 55
24. Y. Liu, W. Wang, B. Fang, F. Ma, Q. Zheng, and P. Deng et al. Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis Eur J Pharmacol 698 2013 95 102