Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis

European Journal of Pharmacology

Volumn 667, Issue 1-3, 2011, Pages 50-55

  Zhong, Zhangfeng ^a,b   Chen, Xiuping ^a   Tan, Wen ^a   Xu, Zengtao ^a   Zhou, Keyuan ^b   Wu, Tie ^b   Cui, Liao ^b   Wang, Yitao ^a  

^a University of Macau   (Macao)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Breast cancer; Cell cycle; Germacrone; Proliferation

Indexed keywords

BIM PROTEIN; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; CYTOTOXIC AGENT; GERMACRONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; CURCUMA LONGA; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RHIZOME;

EID: 80052038761     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.03.041     Document Type: Article

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