Insulin and leptin levels in overweight and normal-weight Iranian adolescents: The CASPIAN-III study

Journal of Research in Medical Sciences

Volumn 19, Issue 5, 2014, Pages 387-390

  Bahrami, Ehsan ^a   Mirmoghtadaee, Parisa ^b   Ardalan, Gelayol ^b   Zarkesh Esfahani, Hamid ^a   Tajaddini, Mohammad Hassan ^a   Haghjooy Javanmard, Shaghayegh ^c   Najafi, Hananeh ^b   Kelishadi, Roya ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Children; Insulin; Leptin; Obesity; Overweight

Indexed keywords

GLUCOSE; INSULIN; LEPTIN;

ADOLESCENT; ADULT; AGE; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY MASS; CARDIOMETABOLIC RISK; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; OBESITY;

EID: 84903128003     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Correia ML, Haynes WG. Leptin, obesity and cardiovascular disease. Curr Opin Nephrol Hypertens 2004;13:215-23.
2. Mirmohammadi SJ, Hafezi R, Mehrparvar AH, Rezaeian B, Akbari H. Prevalence of overweight and obesity among Iranian school children in different ethnicities. Iran J Pediatr 2011;21:514-20.
3. Motlagh ME, Kelishadi R, Ziaoddini H, Mirmoghtadaee P, Poursafa P, Ardalan G, et al. Secular trends in the national prevalence of overweight and obesity during 2007-2009 in 6-year-old Iranian children. J Res Med Sci 2011;16:979-84.
4. Zimmet P, Boyko EJ, Collier GR, de Courten M. Etiology of the metabolic syndrome: Potential role of insulin resistance, leptin resistance, and other players. Ann N Y Acad Sci 1999;892:25-44.
5. Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000;106:473-81.
6. Venner AA, Lyon ME, Doyle-Baker PK. Leptin: A potential biomarker for childhood obesity? Clin Biochem 2006;39:1047-56.
7. Aygun AD, Gungor S, Ustundag B, Gurgoze MK, Sen Y. Proinflammatory cytokines and leptin are increased in serum of prepubertal obese children. Mediators Inflamm 2005;2005:180-3.
8. Mark AL, Correia ML, Rahmouni K, Haynes WG. Selective leptin resistance: A new concept in leptin physiology with cardiovascular implications. J Hypertens 2002;20:1245-50.
9. Martin SS, Qasim A, Reilly MP. Leptin resistance: A possible interface of inflammation and metabolism in obesity-related cardiovascular disease. J Am Coll Cardiol 2008;52:1201-10.
10. Zuo H, Shi Z, Yuan B, Dai Y, Wu G, Hussain A. Association between serum leptin concentrations and insulin resistance: A populationbased study from China. PLoS One 2013;8:e54615.
11. Mente A, Razak F, Blankenberg S, Vuksan V, Davis AD, Miller R, et al. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care 2010;33:1629-34.
12. Huang KC, Lin RC, Kormas N, Lee LT, Chen CY, Gill TP, et al. Plasma leptin is associated with insulin resistance independent of age, body mass index, fat mass, lipids, and pubertal development in nondiabetic adolescents. Int J Obes Relat Metab Disord 2004;28:470-5.
13. Reseland JE, Mundal HH, Hollung K, Haugen F, Zahid N, Anderssen SA, et al. Cigarette smoking may reduce plasma leptin concentration via catecholamines. Prostaglandins Leukot Essent Fatty Acids 2005;73:43-9.
14. Kelishadi R, Heshmat R, Motlagh ME, Majdzadeh R, Keramatian K, Qorbani M, et al. Methodology and Early Findings of the Third Survey of CASPIAN Study: A National School-based Surveillance of Students' High Risk Behaviors. Int J Prev Med 2012;3:394-401.
15. Stylianou C, Galli-Tsinopoulou A, Farmakiotis D, Rousso I, Karamouzis M, Koliakos G, et al. Ghrelin and leptin levels in obese adolescents. Relationship with body fat and insulin resistance. Hormones (Athens) 2007;6:295-303.
16. Hamidi A, Fakhrzadeh H, Moayyeri A, Heshmat R, Ebrahimpour P, Larijani B. Metabolic syndrome and leptin concentrations in obese children. Indian J Pediatr 2006;73:593-6.
17. Hamidi A, Bagheri A, Fakkhrzadeh H, Heshmat R, Moayyeri A, Mahmoudi MJ, et al. The relationship between leptin and insulin resistance in Iranian obese children. J Diab Metab Disord 2004;4:103.
18. Moussa MA, Shaltout AA, Nkansa-Dwamena D, Mourad M, Al-Sheikh N, Agha N, et al. Association of fasting insulin with serum lipids and blood pressure in Kuwaiti children. Metabolism 1998;47:420-4.
19. Shea S, Aymong E, Zybert P, Shamoon H, Tracy RP, Deckelbaum RJ, et al. Obesity, fasting plasma insulin, and C-reactive protein levels in healthy children. Obes Res 2003;11:95-103.
20. Valle M, Gascón F, Martos R, Bermudo F, Ceballos P, Suanes A. Relationship between high plasma leptin concentrations and metabolic syndrome in obese pre-pubertal children. Int J Obes Relat Metab Disord 2003;27:13-8.
21. Plonka M, Toton-Morys A, Adamski P, Suder A, Bielanski W, Dobrzanska MJ, et al. Association of the physical activity with leptin blood serum level, body mass indices and obesity in schoolgirls. J Physiol Pharmacol 2011;62:647-56.