-
1
-
-
84867117207
-
Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab
-
Tejpar S, Celik I, Schlichting M, Sartorius U, Bokemeyer C and Van Cutsem E: Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab. J Clin Oncol 30: 3570-3577, 2012.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3570-3577
-
-
Tejpar, S.1
Celik, I.2
Schlichting, M.3
Sartorius, U.4
Bokemeyer, C.5
Van Cutsem, E.6
-
2
-
-
84862026304
-
Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials
-
Bokemeyer C, Van Cutsem E, Rougier P, Ciardiello F, Heeger S, Schlichting M, Celik I and Köhne CH: Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur J Cancer 48: 1466-1475, 2012.
-
(2012)
Eur J Cancer
, vol.48
, pp. 1466-1475
-
-
Bokemeyer, C.1
Van Cutsem, E.2
Rougier, P.3
Ciardiello, F.4
Heeger, S.5
Schlichting, M.6
Celik, I.7
Köhne, C.H.8
-
3
-
-
84995766806
-
Understanding and targeting resistance to antiangiogenic therapies
-
Clarke JM and Hurwitz HI: Understanding and targeting resistance to antiangiogenic therapies. J Gastrointest Oncol 4: 253-263, 2013.
-
(2013)
J Gastrointest Oncol
, vol.4
, pp. 253-263
-
-
Clarke, J.M.1
Hurwitz, H.I.2
-
4
-
-
84858997017
-
Behavior of seeds and soil in the mechanism of metastasis: A deeper understanding
-
Mathot L and Stenninger J: Behavior of seeds and soil in the mechanism of metastasis: a deeper understanding. Cancer Sci 103: 626-631, 2012.
-
(2012)
Cancer Sci
, vol.103
, pp. 626-631
-
-
Mathot, L.1
Stenninger, J.2
-
5
-
-
84875211731
-
Cancer heterogeneity: Implications for targeted therapeutics
-
Fisher R, Pusztai L and Swanton C: Cancer heterogeneity: implications for targeted therapeutics. Br J Cancer 108: 479-485, 2013.
-
(2013)
Br J Cancer
, vol.108
, pp. 479-485
-
-
Fisher, R.1
Pusztai, L.2
Swanton, C.3
-
6
-
-
84885184379
-
Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer
-
Budinska E, Popovici V, Tejpar S, D'Ario G, Lapique N, Sikora KO, Di Narzo AF, Yan P, Hodgson JG, Weinrich S, Bosman F, Roth A and Delorenzi M: Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer J Pathol 231: 63-76, 2013.
-
(2013)
J Pathol
, vol.231
, pp. 63-76
-
-
Budinska, E.1
Popovici, V.2
Tejpar, S.3
D'Ario, G.4
Lapique, N.5
Sikora, K.O.6
Di Narzo, A.F.7
Yan, P.8
Hodgson, J.G.9
Weinrich, S.10
Bosman, F.11
Roth, A.12
Delorenzi, M.13
-
7
-
-
84884997982
-
Emerging landscape of oncogenic signatures across human cancers
-
Ciriello G, Miller ML, Aksoy BA, Senbabaoglu Y, Schultz N and Sander C: Emerging landscape of oncogenic signatures across human cancers. Nat Genet 45: 1127-1133, 2013.
-
(2013)
Nat Genet
, vol.45
, pp. 1127-1133
-
-
Ciriello, G.1
Miller, M.L.2
Aksoy, B.A.3
Senbabaoglu, Y.4
Schultz, N.5
Sander, C.6
-
8
-
-
78651529782
-
EMT is the dominant program in human colon cancer
-
Loboda A, Nebozhyn MV, Watters JW, Buser CA, Shaw PM, Huang PS, Van't Veer L, Tollenaar RA, Jackson DB, Agrawal D, Dai H and Yeatman TJ: EMT is the dominant program in human colon cancer. BMC Med Genomics 4: 9, 2011.
-
(2011)
BMC Med Genomics
, vol.4
, pp. 9
-
-
Loboda, A.1
Nebozhyn, M.V.2
Watters, J.W.3
Buser, C.A.4
Shaw, P.M.5
Huang, P.S.6
Van'T Veer, L.7
Tollenaar, R.A.8
Jackson, D.B.9
Agrawal, D.10
Dai, H.11
Yeatman, T.J.12
-
9
-
-
84863702079
-
Molecular characterization of circulating tumor cells in human metastatic colorectal cancer
-
Barbazán J, Alonso-Alconada L, Muinelo-Romay L, Vieito M, Abalo A, Alonso-Nocelo M, Candamio S, Gallardo E, Fernández B, Abdulkader I, de Los Ángeles Casares M, Gómez-Tato A, López-López R and Abal M: Molecular characterization of circulating tumor cells in human metastatic colorectal cancer PLoS One 7: e40476, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e40476
-
-
Barbazán, J.1
Alonso-Alconada, L.2
Muinelo-Romay, L.3
Vieito, M.4
Abalo, A.5
Alonso-Nocelo, M.6
Candamio, S.7
Gallardo, E.8
Fernández, B.9
Abdulkader, I.10
De Los Ángeles Casares, M.11
Gómez-Tato, A.12
López-López, R.13
Abal, M.14
-
10
-
-
84886996188
-
Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer
-
Toiyama Y, Yasuda H, Saigusa S, Tanaka K, Inoue Y, Goel A and Kusunoki M: Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer. Carcinogenesis 34: 2548-2557, 2013.
-
(2013)
Carcinogenesis
, vol.34
, pp. 2548-2557
-
-
Toiyama, Y.1
Yasuda, H.2
Saigusa, S.3
Tanaka, K.4
Inoue, Y.5
Goel, A.6
Kusunoki, M.7
-
11
-
-
79953212868
-
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: Prognostic significance of detection for early relapse
-
Lu CY, Uen YH, Tsai HL, Chuang SC, Hou MF, Wu DC, Juo SH, Lin SR and Wang JY: Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse. Br J Cancer 104: 1178-1184, 2011.
-
(2011)
Br J Cancer
, vol.104
, pp. 1178-1184
-
-
Lu, C.Y.1
Uen, Y.H.2
Tsai, H.L.3
Chuang, S.C.4
Hou, M.F.5
Wu, D.C.6
Juo, S.H.7
Lin, S.R.8
Wang, J.Y.9
-
12
-
-
77952419985
-
Circulating tumor cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents
-
Tol J, Koopman M, Miller MC, Tibbe A, Cats A, Creemers GJ, Vos AH, Nagtegaal ID, Terstappen LW and Punt CJ: Circulating tumor cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents. Ann Oncol 21: 1006-1012, 2010.
-
(2010)
Ann Oncol
, vol.21
, pp. 1006-1012
-
-
Tol, J.1
Koopman, M.2
Miller, M.C.3
Tibbe, A.4
Cats, A.5
Creemers, G.J.6
Vos, A.H.7
Nagtegaal, I.D.8
Terstappen, L.W.9
Punt, C.J.10
-
13
-
-
67650366758
-
Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer
-
Yen LC, Yeh YS, Chen CW, Wang HM, Tsai HL, Lu CY, Chang YT, Chu KS, Lin SR and Wang JY: Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer. Clin Cancer Res 15: 4508-4513, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4508-4513
-
-
Yen, L.C.1
Yeh, Y.S.2
Chen, C.W.3
Wang, H.M.4
Tsai, H.L.5
Lu, C.Y.6
Chang, Y.T.7
Chu, K.S.8
Lin, S.R.9
Wang, J.Y.10
-
14
-
-
77951665381
-
Prognostic significance of circulating tumor cells following surgical resection of colorectal cancers: A systematic review
-
Peach G, Kim C, Zacharakis E, Purkayastha S and Ziprin P: Prognostic significance of circulating tumor cells following surgical resection of colorectal cancers: a systematic review. Br J Cancer 102: 1327-1334, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 1327-1334
-
-
Peach, G.1
Kim, C.2
Zacharakis, E.3
Purkayastha, S.4
Ziprin, P.5
-
15
-
-
84868632393
-
Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients
-
De Albuquerque A, Kubisch I, Stölzel U, Ernst D, Boese-Landgraf J, Breier G, Stamminger G, Fersis N and Kaul S: Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients. J Transl Med 10: 222, 2012.
-
(2012)
J Transl Med
, vol.10
, pp. 222
-
-
De Albuquerque, A.1
Kubisch, I.2
Stölzel, U.3
Ernst, D.4
Boese-Landgraf, J.5
Breier, G.6
Stamminger, G.7
Fersis, N.8
Kaul, S.9
-
16
-
-
84863660714
-
Influence of surgical manipulation and surgical modality on the molecular detection of circulating tumor cells from colorectal cancer
-
Park SY, Choi GS, Park JS, Kim HJ, Ryuk JP and Choi WH: Influence of surgical manipulation and surgical modality on the molecular detection of circulating tumor cells from colorectal cancer. J Korean Surg Soc 82: 356-364, 2012.
-
(2012)
J Korean Surg Soc
, vol.82
, pp. 356-364
-
-
Park, S.Y.1
Choi, G.S.2
Park, J.S.3
Kim, H.J.4
Ryuk, J.P.5
Choi, W.H.6
-
17
-
-
77950458280
-
Meta-Analysis shows that detection of circulating tumor cells indicates poor prognosis in patients with colorectal cancer
-
Rahbari NN, Aigner M, Thorlund K, Mollberg N, Motschall E, Jensen K, Diener MK, Büchler MW, Koch M and Weitz J: Meta-Analysis shows that detection of circulating tumor cells indicates poor prognosis in patients with colorectal cancer. Gastroenterology 138: 1714-1726, 2010.
-
(2010)
Gastroenterology
, vol.138
, pp. 1714-1726
-
-
Rahbari, N.N.1
Aigner, M.2
Thorlund, K.3
Mollberg, N.4
Motschall, E.5
Jensen, K.6
Diener, M.K.7
Büchler, M.W.8
Koch, M.9
Weitz, J.10
-
18
-
-
84878845360
-
Lack of prognostic significance of conventional peritoneal cytology in colorectal and gastric cancers: Results of EVOCAPE 2 multicentre prospective study
-
Cotte E, Peyrat P, Piaton E, Chapuis F, Rivoire M, Glehen O, Arvieux C, Mabrut J Y, Chipponi J, Gilly FN; EVOCAPE group. Lack of prognostic significance of conventional peritoneal cytology in colorectal and gastric cancers: results of EVOCAPE 2 multicentre prospective study. Eur J Surg Oncol 39: 707-714, 2013.
-
(2013)
Eur J Surg Oncol
, vol.39
, pp. 707-714
-
-
Cotte, E.1
Peyrat, P.2
Piaton, E.3
Chapuis, F.4
Rivoire, M.5
Glehen, O.6
Arvieux, C.7
Mabrut, J.Y.8
Chipponi, J.9
Gilly, F.N.10
-
19
-
-
65549133014
-
Coordination of intratumoral immune reaction and human colorectal cancer recurrence
-
Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH and Galon J: Coordination of intratumoral immune reaction and human colorectal cancer recurrence. Cancer Res 69: 2685-2693, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 2685-2693
-
-
Camus, M.1
Tosolini, M.2
Mlecnik, B.3
Pagès, F.4
Kirilovsky, A.5
Berger, A.6
Costes, A.7
Bindea, G.8
Charoentong, P.9
Bruneval, P.10
Trajanoski, Z.11
Fridman, W.H.12
Galon, J.13
-
20
-
-
84884151496
-
Tumor-Associated macrophages and neutrophils in cancer
-
Galdiero MR, Bonavita E, Barajon I, Garlanda C, Mantovani A and Jaillon S: Tumor-Associated macrophages and neutrophils in cancer. Immunobiology 218: 1402-1410, 2013.
-
(2013)
Immunobiology
, vol.218
, pp. 1402-1410
-
-
Galdiero, M.R.1
Bonavita, E.2
Barajon, I.3
Garlanda, C.4
Mantovani, A.5
Jaillon, S.6
-
21
-
-
84867504992
-
The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer
-
Edin S, Wikberg ML, Dahlin AM, Rutegård J, Öberg Å, Oldenborg PA and Palmqvist R: The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer. PLoS One 7: e47045, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e47045
-
-
Edin, S.1
Wikberg, M.L.2
Dahlin, A.M.3
Rutegård, J.4
Öberg, A.5
Oldenborg, P.A.6
Palmqvist, R.7
-
22
-
-
84884237300
-
Phenotypic skewing of macrophages in vitro by secreted factors from colorectal cancer cells
-
Edin S, Wikberg ML, Rutegård J, Oldenborg PA and Palmqvist R: Phenotypic skewing of macrophages in vitro by secreted factors from colorectal cancer cells. PLoS One 8: e74982, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e74982
-
-
Edin, S.1
Wikberg, M.L.2
Rutegård, J.3
Oldenborg, P.A.4
Palmqvist, R.5
-
23
-
-
36349011403
-
Activation of NF-κB by AKT up-regulates Snail expression and induces epithelium-mesenchyme transition
-
Julien S, Puig I, Caretti E, Bonaventure J, Nelles L, van Roy F, Dargemont C, de Herreros AG, Bellacosa A and Larue L: Activation of NF-κB by AKT up-regulates Snail expression and induces epithelium-mesenchyme transition. Oncogene 26: 7445-7456, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 7445-7456
-
-
Julien, S.1
Puig, I.2
Caretti, E.3
Bonaventure, J.4
Nelles, L.5
Van Roy, F.6
Dargemont, C.7
De Herreros, A.G.8
Bellacosa, A.9
Larue, L.10
-
24
-
-
84867860430
-
Epithelial-mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy
-
Bhangu A, Wood G, Mirnezami A, Darzi A, Tekkis P and Goldin R: Epithelial-mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy. Surg Oncol 21: 316-323, 2012.
-
(2012)
Surg Oncol
, vol.21
, pp. 316-323
-
-
Bhangu, A.1
Wood, G.2
Mirnezami, A.3
Darzi, A.4
Tekkis, P.5
Goldin, R.6
-
25
-
-
73349142719
-
In situ cytotoxic and memory T-cells predict outcome in patients with early-stage colorectal cancer
-
Pagès F, Kirilovsky A, Mlecnik B, Asslaber M, Tosolini M, Bindea G, Lagorce C, Wind P, Marliot F, Bruneval P, Zatloukal K, Trajanoski Z, Berger A, Fridman WH and Galon J: In situ cytotoxic and memory T-cells predict outcome in patients with early-stage colorectal cancer. J Clin Oncol 27: 5944-5951, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5944-5951
-
-
Pagès, F.1
Kirilovsky, A.2
Mlecnik, B.3
Asslaber, M.4
Tosolini, M.5
Bindea, G.6
Lagorce, C.7
Wind, P.8
Marliot, F.9
Bruneval, P.10
Zatloukal, K.11
Trajanoski, Z.12
Berger, A.13
Fridman, W.H.14
Galon, J.15
-
26
-
-
84856545781
-
Tumor infiltration by T-lymphocytes expressing chemokine receptor 7 (CCR7) is predictive of favorable outcome in patients with advanced colorectal carcinoma
-
Correale P, Rotundo MS, Botta C, Del Vecchio MT, Ginanneschi C, Licchetta A, Conca R, Apollinari S, De Luca F, Tassone P and Tagliaferri P: Tumor infiltration by T-lymphocytes expressing chemokine receptor 7 (CCR7) is predictive of favorable outcome in patients with advanced colorectal carcinoma. Clin Cancer Res 18: 850-857, 2012.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 850-857
-
-
Correale, P.1
Rotundo, M.S.2
Botta, C.3
Del Vecchio, M.T.4
Ginanneschi, C.5
Licchetta, A.6
Conca, R.7
Apollinari, S.8
De Luca, F.9
Tassone, P.10
Tagliaferri, P.11
-
27
-
-
0347785480
-
Control of regulatory T-cell development by the transcription factor Foxp3
-
Hori S, Nomura T and Sakaguchi S: Control of regulatory T-cell development by the transcription factor Foxp3. Science 299: 1057-1061, 2003.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
28
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T-cells and NF-κB to repress cytokine gene expression and effect or functions of T-helper cells
-
Bettelli E, Dastrange M and Oukka M: Foxp3 interacts with nuclear factor of activated T-cells and NF-κB to repress cytokine gene expression and effect or functions of T-helper cells. Proc Natl Acad Sci USA 102: 5138-5143, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
29
-
-
58249089749
-
+ T-regulatory cells show strong prognostic significance in colorectal cancer
-
+ T-regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 27: 186-192, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 186-192
-
-
Salama, P.1
Phillips, M.2
Grieu, F.3
Morris, M.4
Zeps, N.5
Joseph, D.6
Platell, C.7
Iacopetta, B.8
-
30
-
-
84873822300
-
Expression of FOXP3 in colorectal cancer but not in T-reg cells correlates with disease progression in patients with colorectal cancer
-
Kim M, Grimmig T, Grimm M, Lazariotou M, Meier E, Rosenwald A, Tsaur I, Blaheta R, Heemann U, Germer CT, Waaga-Gasser AM and Gasser M: Expression of FOXP3 in colorectal cancer but not in T-reg cells correlates with disease progression in patients with colorectal cancer. PLoS One 8: e53630, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e53630
-
-
Kim, M.1
Grimmig, T.2
Grimm, M.3
Lazariotou, M.4
Meier, E.5
Rosenwald, A.6
Tsaur, I.7
Blaheta, R.8
Heemann, U.9
Germer, C.T.10
Waaga-Gasser, A.M.11
Gasser, M.12
-
31
-
-
84863274470
-
Tumor-derived chemokine CCL5 enhances TGF-β-mediated killing of CD8(+) T-cells in colon cancer by T-regulatory cells
-
Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng HM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT and Lin CY: Tumor-derived chemokine CCL5 enhances TGF-β-mediated killing of CD8(+) T-cells in colon cancer by T-regulatory cells. Cancer Res 72: 1092-1102, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 1092-1102
-
-
Chang, L.Y.1
Lin, Y.C.2
Mahalingam, J.3
Huang, C.T.4
Chen, T.W.5
Kang, C.W.6
Peng, H.M.7
Chu, Y.Y.8
Chiang, J.M.9
Dutta, A.10
Day, Y.J.11
Chen, T.C.12
Yeh, C.T.13
Lin, C.Y.14
-
32
-
-
77955725489
-
+ T-regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients
-
+ T-regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. Clin Cancer Res 16: 4105-4112, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4105-4112
-
-
Deng, L.1
Zhang, H.2
Luan, Y.3
Zhang, J.4
Xing, Q.5
Dong, S.6
Wu, X.7
Liu, M.8
Wang, S.9
-
33
-
-
74949093260
-
Nodal staging score: A tool to assess adequate staging of node-negative colon cancer
-
Gönen M, Schrag D and Weiser MR: Nodal staging score: A tool to assess adequate staging of node-negative colon cancer. J Clin Oncol 27: 6166-6171, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6166-6171
-
-
Gönen, M.1
Schrag, D.2
Weiser, M.R.3
-
34
-
-
83255175580
-
Which is the most suitable classification for colorectal cancer log odds the number or the ratio of positive lymph nodes?
-
Song Y-X, Gao P, Wang Z-N, Tong LL, Xu YY, Sun Z, Xing CZ and Xu HM: Which is the most suitable classification for colorectal cancer, log odds, the number or the ratio of positive lymph nodes? PLoS One 6: e28937, 2011.
-
(2011)
PLoS One
, vol.6
, pp. e28937
-
-
Song, Y.-X.1
Gao, P.2
Wang, Z.-N.3
Tong, L.L.4
Xu, Y.Y.5
Sun, Z.6
Xing, C.Z.7
Xu, H.M.8
-
35
-
-
84873303427
-
Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis
-
Zhao L, Lim SY, Gordon-Weeks AN, Tapmeier TT, Im JH, Cao Y, Beech J, Allen D, Smart S and Muschel RJ: Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis. Hepatology 57: 829-839, 2013.
-
(2013)
Hepatology
, vol.57
, pp. 829-839
-
-
Zhao, L.1
Lim, S.Y.2
Gordon-Weeks, A.N.3
Tapmeier, T.T.4
Im, J.H.5
Cao, Y.6
Beech, J.7
Allen, D.8
Smart, S.9
Muschel, R.J.10
-
36
-
-
84886789666
-
Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1(+) Myeloid cells and facilitate liver metastasis
-
Itatani Y, Kawada K, Fujishita T, Kakizaki F, Hirai H, Matsumoto T, Iwamoto M, Inamoto S, Hatano E, Hasegawa S, Maekawa T, Uemoto S, Sakai Y and Taketo MM: Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1(+) Myeloid cells and facilitate liver metastasis. Gastroenterology 145: 1064-1075, 2013.
-
(2013)
Gastroenterology
, vol.145
, pp. 1064-1075
-
-
Itatani, Y.1
Kawada, K.2
Fujishita, T.3
Kakizaki, F.4
Hirai, H.5
Matsumoto, T.6
Iwamoto, M.7
Inamoto, S.8
Hatano, E.9
Hasegawa, S.10
Maekawa, T.11
Uemoto, S.12
Sakai, Y.13
Taketo, M.M.14
-
37
-
-
15944400631
-
Hematopoietic cells regulate the angiogenic switch during tumorigenesis
-
Okamoto R, Ueno M, Yamada Y, Takahashi N, Sano H, Suda T, Takakura N: Hematopoietic cells regulate the angiogenic switch during tumorigenesis. Blood 105: 2757-2763, 2005.
-
(2005)
Blood
, vol.105
, pp. 2757-2763
-
-
Okamoto, R.1
Ueno, M.2
Yamada, Y.3
Takahashi, N.4
Sano, H.5
Suda, T.6
Takakura, N.7
-
38
-
-
78049517433
-
Mesenchymal stem cells enhance growth and metastasis of colon cancer
-
Shinagawa K, Kitadai Y, Tanaka M, Sumida T, Kodama M, Higashi Y, Tanaka S, Yasui W and Chayama K: Mesenchymal stem cells enhance growth and metastasis of colon cancer. Int J Cancer 127: 2323-2333, 2010.
-
(2010)
Int J Cancer
, vol.127
, pp. 2323-2333
-
-
Shinagawa, K.1
Kitadai, Y.2
Tanaka, M.3
Sumida, T.4
Kodama, M.5
Higashi, Y.6
Tanaka, S.7
Yasui, W.8
Chayama, K.9
-
39
-
-
84880182893
-
Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity
-
Li T, Yi S, Liu W, Jia C, Wang G, Hua X, Tai Y, Zhang Q and Chen G: Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity. Med Oncol 30: 663, 2013.
-
(2013)
Med Oncol
, vol.30
, pp. 663
-
-
Li, T.1
Yi, S.2
Liu, W.3
Jia, C.4
Wang, G.5
Hua, X.6
Tai, Y.7
Zhang, Q.8
Chen, G.9
-
40
-
-
84885079983
-
FGFR4 Promotes Stroma-induced epithelial-to-mesenchymal transition in colorectal cancer
-
Liu R, Li J, Xie K, Zhang T, Lei Y, Chen Y, Zhang L, Huang K, Wang K, Wu H, Wu M, Nice EC, Huang C and Wei Y: FGFR4 Promotes Stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. Cancer Res 73: 5926-5935, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 5926-5935
-
-
Liu, R.1
Li, J.2
Xie, K.3
Zhang, T.4
Lei, Y.5
Chen, Y.6
Zhang, L.7
Huang, K.8
Wang, K.9
Wu, H.10
Wu, M.11
Nice, E.C.12
Huang, C.13
Wei, Y.14
-
41
-
-
84860521108
-
Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1
-
Rongze Lu, Maciej Kujawski, Hao Pan and Shively JE: Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1. Cancer Res 72: 2239-2250, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 2239-2250
-
-
Lu, R.1
Kujawski, M.2
Pan, H.3
Shively, J.E.4
-
42
-
-
84903286650
-
Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells
-
Sep 2. (Epub ahead of print)
-
Suman S, Kurisetty V, Das TP, Vadodkar A, Ramos G, Lakshmanaswamy R and Damodaran C: Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells. Mol Carcinog. 2013 Sep 2. (Epub ahead of print)
-
(2013)
Mol Carcinog.
-
-
Suman, S.1
Kurisetty, V.2
Das, T.P.3
Vadodkar, A.4
Ramos, G.5
Lakshmanaswamy, R.6
Damodaran, C.7
-
43
-
-
33646849272
-
The correlation between colorectal cancer rates of proliferation and apoptosis and systemic cytokine levels; Plus their influence upon survival
-
Evans C, Morrison I, Heriot AG, Bartlett JB, Finlayson C, Dalgleish AG and Kumar D: The correlation between colorectal cancer rates of proliferation and apoptosis and systemic cytokine levels; plus their influence upon survival. Br J Cancer 94: 1412-1419, 2006.
-
(2006)
Br J Cancer
, vol.94
, pp. 1412-1419
-
-
Evans, C.1
Morrison, I.2
Heriot, A.G.3
Bartlett, J.B.4
Finlayson, C.5
Dalgleish, A.G.6
Kumar, D.7
-
44
-
-
84899786498
-
Prognostic role of neutrophil-to-lymphocyte ratio in colorectal cancer: A systematic review and meta-Analysis
-
Oct 10. (Epub ahead of print)
-
Li MX, Liu XM, Zhang XF, Zhang JF, Wang WL, Zhu Y, Dong J, Cheng JW, Liu ZW, Ma L and Lv Y: Prognostic role of neutrophil-to-lymphocyte ratio in colorectal cancer: A systematic review and meta-Analysis. Int J Cancer. 2013 Oct 10. (Epub ahead of print)
-
(2013)
Int J Cancer.
-
-
Li, M.X.1
Liu, X.M.2
Zhang, X.F.3
Zhang, J.F.4
Wang, W.L.5
Zhu, Y.6
Dong, J.7
Cheng, J.W.8
Liu, Z.W.9
Ma, L.10
Lv, Y.11
-
45
-
-
84906315448
-
A Preoperative neutrophil to lymphocyte ratio of 3 predicts disease-free survival after curative elective colorectal cancer surgery
-
Oct 3. (Epub ahead of print)
-
Malietzis G, Giacometti M, Askari A, Nachiappan S, Kennedy RH, Faiz OD, Aziz O and Jenkins JT: A Preoperative neutrophil to lymphocyte ratio of 3 predicts disease-free survival after curative elective colorectal cancer surgery. Ann Surg. 2013 Oct 3. (Epub ahead of print)
-
(2013)
Ann Surg.
-
-
Malietzis, G.1
Giacometti, M.2
Askari, A.3
Nachiappan, S.4
Kennedy, R.H.5
Faiz, O.D.6
Aziz, O.7
Jenkins, J.T.8
-
46
-
-
84883307604
-
A high preoperative neutrophil-to-lymphocyte ratio is associated with poor survival in patients with colorectal cancer
-
Shibutani M, Maeda K, Nagahara H, Noda E, Ohtani H, Nishiguchi Y and Hirakawa K: A high preoperative neutrophil-to-lymphocyte ratio is associated with poor survival in patients with colorectal cancer. Anticancer Res 33: 3291-3294, 2013.
-
(2013)
Anticancer Res
, vol.33
, pp. 3291-3294
-
-
Shibutani, M.1
Maeda, K.2
Nagahara, H.3
Noda, E.4
Ohtani, H.5
Nishiguchi, Y.6
Hirakawa, K.7
-
47
-
-
84880576750
-
Initial neutrophil lymphocyte ratio is superior to platelet lymphocyte ratio as an adverse prognostic and predictive factor in metastatic colorectal cancer
-
He W, Yin C, Guo G, Jiang C, Wang F, Qiu H, Chen X, Rong R, Zhang B and Xia L: Initial neutrophil lymphocyte ratio is superior to platelet lymphocyte ratio as an adverse prognostic and predictive factor in metastatic colorectal cancer. Med Oncol 30: 439, 2013.
-
(2013)
Med Oncol
, vol.30
, pp. 439
-
-
He, W.1
Yin, C.2
Guo, G.3
Jiang, C.4
Wang, F.5
Qiu, H.6
Chen, X.7
Rong, R.8
Zhang, B.9
Xia, L.10
-
48
-
-
60449118650
-
Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy
-
Kishi Y, Kopetz S, Chun YS, Palavecino M, Abdalla EK and Vauthey JN: Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy. Ann Surg Oncol 16: 614-622, 2009.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 614-622
-
-
Kishi, Y.1
Kopetz, S.2
Chun, Y.S.3
Palavecino, M.4
Abdalla, E.K.5
Vauthey, J.N.6
-
49
-
-
84880253796
-
Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer
-
Guthrie GJ, Roxburgh CS, Farhan-Alanie OM, Horgan PG and McMillan DC: Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer. Br J Cancer 109: 24-28, 2013.
-
(2013)
Br J Cancer
, vol.109
, pp. 24-28
-
-
Guthrie, G.J.1
Roxburgh, C.S.2
Farhan-Alanie, O.M.3
Horgan, P.G.4
McMillan, D.C.5
-
50
-
-
80755128486
-
A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study
-
Proctor MJ, Morrison DS, Talwar D, Balmer SM, Fletcher CD, O'Reilly DS, Foulis AK, Horgan PG and McMillan DC: A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. Eur J Cancer 47: 2633-2641, 2011.
-
(2011)
Eur J Cancer
, vol.47
, pp. 2633-2641
-
-
Proctor, M.J.1
Morrison, D.S.2
Talwar, D.3
Balmer, S.M.4
Fletcher, C.D.5
O'Reilly, D.S.6
Foulis, A.K.7
Horgan, P.G.8
McMillan, D.C.9
-
51
-
-
84881118260
-
Combination of platelet count and neutrophil to lymphocyte ratio is a useful predictor of postoperative survival in patients with colorectal cancer
-
Ishizuka M, Nagata H, Takagi K, Iwasaki Y and Kubota K: Combination of platelet count and neutrophil to lymphocyte ratio is a useful predictor of postoperative survival in patients with colorectal cancer. Br J Cancer 109: 401-407, 2013.
-
(2013)
Br J Cancer
, vol.109
, pp. 401-407
-
-
Ishizuka, M.1
Nagata, H.2
Takagi, K.3
Iwasaki, Y.4
Kubota, K.5
-
52
-
-
84863721491
-
+ T-cells by regulatory T-cells is associated with progression of human colorectal cancer
-
+ T-cells by regulatory T-cells is associated with progression of human colorectal cancer. Gut 61: 1163-1171, 2012.
-
(2012)
Gut
, vol.61
, pp. 1163-1171
-
-
Betts, G.1
Jones, E.2
Junaid, S.3
El-Shanawany, T.4
Scurr, M.5
Mizen, P.6
Kumar, M.7
Jones, S.8
Rees, B.9
Williams, G.10
Gallimore, A.11
Godkin, A.12
-
53
-
-
84863484555
-
Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypo-proteinemia in patients with cancer
-
Ohki S, Shibata M, Gonda K, Machida T, Shimura T, Nakamura I, Ohtake T, Koyama Y, Suzuki S, Ohto H and Takenoshita S: Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypo-proteinemia in patients with cancer. Oncol Rep 28: 453-458, 2012.
-
(2012)
Oncol Rep
, vol.28
, pp. 453-458
-
-
Ohki, S.1
Shibata, M.2
Gonda, K.3
Machida, T.4
Shimura, T.5
Nakamura, I.6
Ohtake, T.7
Koyama, Y.8
Suzuki, S.9
Ohto, H.10
Takenoshita, S.11
-
54
-
-
0029841427
-
Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses
-
Otsuji M, Kimura Y, Aoe T, Okamoto Y and Saito T: Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci USA 93: 13119-13124, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13119-13124
-
-
Otsuji, M.1
Kimura, Y.2
Aoe, T.3
Okamoto, Y.4
Saito, T.5
-
55
-
-
37549030135
-
Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases-Activation of cell invasion and migration pathways
-
Man K, Ng KT, Lo CM, Ho JW, Sun BS, Sun CK, Lee TK, Poon RT and Fan ST: Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases-Activation of cell invasion and migration pathways. Liver Transpl 13: 1669-1677, 2007.
-
(2007)
Liver Transpl
, vol.13
, pp. 1669-1677
-
-
Man, K.1
Ng, K.T.2
Lo, C.M.3
Ho, J.W.4
Sun, B.S.5
Sun, C.K.6
Lee, T.K.7
Poon, R.T.8
Fan, S.T.9
-
56
-
-
0036064676
-
Hepatic ischemia-reperfusion promotes liver metastasis of colon cancer
-
Doi K, Horiuchi T, Uchinami M, Tabo T, Tabo T, Kimura N, Yokomachi J, Yoshida M and Tanaka K: Hepatic ischemia-reperfusion promotes liver metastasis of colon cancer. J Surg Res 105: 243-247, 2002.
-
(2002)
J Surg Res
, vol.105
, pp. 243-247
-
-
Doi, K.1
Horiuchi, T.2
Uchinami, M.3
Tabo, T.4
Tabo, T.5
Kimura, N.6
Yokomachi, J.7
Yoshida, M.8
Tanaka, K.9
-
57
-
-
76949084622
-
TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
-
Wu Y and Zhou BP: TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion. Br J Cancer 102: 639-644, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 639-644
-
-
Wu, Y.1
Zhou, B.P.2
-
58
-
-
84880286579
-
Circulating IL-6 concentrations link tumour necrosis and systemic and local inflammatory responses in patients undergoing resection for colorectal cancer
-
Guthrie GJ, Roxburgh CS, Richards CH, Horgan PG and McMillan DC: Circulating IL-6 concentrations link tumour necrosis and systemic and local inflammatory responses in patients undergoing resection for colorectal cancer. Br J Cancer 109: 131-137, 2013.
-
(2013)
Br J Cancer
, vol.109
, pp. 131-137
-
-
Guthrie, G.J.1
Roxburgh, C.S.2
Richards, C.H.3
Horgan, P.G.4
McMillan, D.C.5
-
59
-
-
0037011659
-
Arterio-venous gradients of IL-6, plasma and serum VEGF and D-dimers in human cancer
-
Salgado R, Benoy I, Weytjens R, Van Bockstaele D, Van Marck E, Huget P, Hoylaerts M, Vermeulen P and Dirix LY: Arterio-venous gradients of IL-6, plasma and serum VEGF and D-dimers in human cancer. Br J Cancer 87: 1437-1444, 2002.
-
(2002)
Br J Cancer
, vol.87
, pp. 1437-1444
-
-
Salgado, R.1
Benoy, I.2
Weytjens, R.3
Van Bockstaele, D.4
Van Marck, E.5
Huget, P.6
Hoylaerts, M.7
Vermeulen, P.8
Dirix, L.Y.9
-
60
-
-
84878828739
-
Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: A meta-Analysis
-
Groot Koerkamp B, Rahbari NN, Büchler MW, Koch M and Weitz J: Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: a meta-Analysis. Ann Surg Oncol 20: 2156-2165, 2013.
-
(2013)
Ann Surg Oncol
, vol.20
, pp. 2156-2165
-
-
Groot Koerkamp, B.1
Rahbari, N.N.2
Büchler, M.W.3
Koch, M.4
Weitz, J.5
-
61
-
-
34948896998
-
Where is VEGF in the body? A meta-Analysis of VEGF distribution in cancer
-
Kut C, Mac Gabhann F and Popel AS: Where is VEGF in the body? A meta-Analysis of VEGF distribution in cancer. Br J Cancer 97: 978-85, 2007.
-
(2007)
Br J Cancer
, vol.97
, pp. 978-985
-
-
Kut, C.1
Mac Gabhann, F.2
Popel, A.S.3
-
62
-
-
84865143174
-
VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients
-
Peterson JE, Zurakowski D, Italiano JE Jr., Michel LV, Connors S, Oenick M, D'Amato RJ, Klement GL and Folkman J: VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients. Angiogenesis 15: 265-273, 2012.
-
(2012)
Angiogenesis
, vol.15
, pp. 265-273
-
-
Peterson, J.E.1
Zurakowski, D.2
Italiano, J.E.3
Michel, L.V.4
Connors, S.5
Oenick, M.6
D'Amato, R.J.7
Klement, G.L.8
Folkman, J.9
-
63
-
-
84888373513
-
Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis
-
Braemswig KH, Poettler M, Unseld M, Wrba F, Uhrin P, Zimmermann W, Zielinski CC and Prager GW: Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis. Cancer Res 73: 6584-6596, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 6584-6596
-
-
Braemswig, K.H.1
Poettler, M.2
Unseld, M.3
Wrba, F.4
Uhrin, P.5
Zimmermann, W.6
Zielinski, C.C.7
Prager, G.W.8
-
64
-
-
34547915950
-
Microfluidic reveals generation of platelet-strings on tumor-Activated endothelium
-
Goerge T, Kleinerüschkamp F, Barg A, Schnaeker EM, Huck V, Schneider MF, Steinhoff M and Schneider SW: Microfluidic reveals generation of platelet-strings on tumor-Activated endothelium. Thromb Haemost 98: 283-286, 2007.
-
(2007)
Thromb Haemost
, vol.98
, pp. 283-286
-
-
Goerge, T.1
Kleinerüschkamp, F.2
Barg, A.3
Schnaeker, E.M.4
Huck, V.5
Schneider, M.F.6
Steinhoff, M.7
Schneider, S.W.8
-
65
-
-
84864650304
-
Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-Associated thrombosis
-
Demers M, Krause DS, Schatzberg D, Martinod K, Voorhees JR, Fuchs TA, Scadden DT and Wagner DD: Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-Associated thrombosis. Proc Natl Acad Sci USA 109: 13076-13081, 2012.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 13076-13081
-
-
Demers, M.1
Krause, D.S.2
Schatzberg, D.3
Martinod, K.4
Voorhees, J.R.5
Fuchs, T.A.6
Scadden, D.T.7
Wagner, D.D.8
-
66
-
-
84881249503
-
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
-
Jul 1 (Epub ahead of print)
-
Cools-Lartigue J, Spicer J, McDonald B, Gowing S, Chow S, Giannias B, Bourdeau F, Kubes P and Ferri L: Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest. 2013 Jul 1. pii: 67484. doi: 10.1172/JCI67484. (Epub ahead of print).
-
(2013)
J Clin Invest.
-
-
Cools-Lartigue, J.1
Spicer, J.2
McDonald, B.3
Gowing, S.4
Chow, S.5
Giannias, B.6
Bourdeau, F.7
Kubes, P.8
Ferri, L.9
-
67
-
-
84877756860
-
Spreaders and sponges define metastasis in lung cancer: A Markov chain Monte-Carlo mathematical model
-
Newton PK, Mason J, Bethel K, Bazhenova L, Nieva J, Norton L and Kuhn P: Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte-Carlo mathematical model. Cancer Res 73: 2760-2769, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 2760-2769
-
-
Newton, P.K.1
Mason, J.2
Bethel, K.3
Bazhenova, L.4
Nieva, J.5
Norton, L.6
Kuhn, P.7
-
68
-
-
84875698851
-
Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer
-
Comen E, Morris PG and Norton L: Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer. J Mammary Gland Biol Neoplasia 17: 241-249, 2012.
-
(2012)
J Mammary Gland Biol Neoplasia
, vol.17
, pp. 241-249
-
-
Comen, E.1
Morris, P.G.2
Norton, L.3
-
69
-
-
79957510776
-
Sentinel lymph node procedure in colon and rectal cancer: A systematic review and meta-Analysis
-
Van der Pas MH, Meijer S, Hoekstra OS, Riphagen II, de Vet HC, Knol DL, van Grieken NC and Meijerink WJ: Sentinel lymph node procedure in colon and rectal cancer: a systematic review and meta-Analysis. Lancet Oncol 12: 540-550, 2011.
-
(2011)
Lancet Oncol
, vol.12
, pp. 540-550
-
-
Van Der Pas, M.H.1
Meijer, S.2
Hoekstra, O.S.3
Riphagen, I.I.4
De Vet, H.C.5
Knol, D.L.6
Van Grieken, N.C.7
Meijerink, W.J.8
|