Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays

Chemistry and Biology

Volumn 21, Issue 6, 2014, Pages 743-753

  Stossi, Fabio ^a   Bolt, Michael J ^a   Ashcroft, Felicity J ^a   Lamerdin, Jane E ^b   Melnick, Jonathan S ^b   Powell, Reid T ^c   Dandekar, Radhika D ^a   Mancini, Maureen G ^a   Walker, Cheryl L ^c   Westwick, John K ^b   Mancini, Michael A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b OdysseyThera   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DNA; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; RNA POLYMERASE II; TETRABROMOBISPHENOL A; BENZHYDRYL DERIVATIVE; PHENOL DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOSENSOR; BREAST CANCER CELL LINE; CELL COUNT; CELL DENSITY; CELL PROLIFERATION ASSAY; CHEMICAL STRUCTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; ENVIRONMENTAL EXPOSURE; ESTROGEN ACTIVITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MICROSCOPY; PRIORITY JOURNAL; STEADY STATE; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; HELA CELL LINE; MCF 7 CELL LINE; METABOLISM; STRUCTURE ACTIVITY RELATION; TUMOR CELL CULTURE;

BENZHYDRYL COMPOUNDS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MCF-7 CELLS; MICROSCOPY; PHENOLS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84902968987     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.03.013     Document Type: Article

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