Celecoxib suppresses the phosphorylation of STAT3 protein and can enhance the radiosensitivity of medulloblastoma-derived cancer stem-like cells

International Journal of Molecular Sciences

Volumn 15, Issue 6, 2014, Pages 11013-11029

  Yang, Meng Yin ^a,b,c,d   Lee, Hsu Tung ^b,c   Chen, Chien Min ^e   Shen, Chiung Chyi ^b,c,d   Ma, Hsin I ^b,f  

^a Jan ai Hospital   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d HUNGKUANG UNIVERSITY   (Taiwan)

^e CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^f TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Cancer stem like cells; CD133; Celecoxib; Medulloblastoma; Nestin; STAT3

Indexed keywords

CD133 ANTIGEN; CELECOXIB; EPIDERMAL GROWTH FACTOR; FIREFLY LUCIFERASE; JANUS KINASE; PROTEIN BCL 2; STAT3 PROTEIN; CYCLOOXYGENASE 2 INHIBITOR; GLYCOPROTEIN; JANUS KINASE 1; LEUKOCYTE ANTIGEN; PEPTIDE; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN TUMOR; CANCER RECURRENCE; CANCER STEM CELL; CARCINOGENESIS; CELL SURVIVAL; COLONY FORMATION; FLOW CYTOMETRY; IONIZING RADIATION; MEDULLOBLASTOMA; MICROARRAY ANALYSIS; MOUSE; NICK END LABELING; NONHUMAN; ONCOGENE C MYC; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; WESTERN BLOTTING; ANIMAL; CEREBELLAR NEOPLASMS; DRUG EFFECTS; HUMAN; METABOLISM; MORTALITY; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; RADIATION DOSE; RADIATION RESPONSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UPREGULATION; XENOGRAFT;

ANIMALS; ANTIGENS, CD; APOPTOSIS; CELL LINE, TUMOR; CEREBELLAR NEOPLASMS; CYCLOOXYGENASE 2 INHIBITORS; GLYCOPROTEINS; HUMANS; JANUS KINASE 1; MEDULLOBLASTOMA; MICE; MICE, NUDE; NEOPLASTIC STEM CELLS; PEPTIDES; PHOSPHORYLATION; PYRAZOLES; RADIATION TOLERANCE; RADIATION, IONIZING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SULFONAMIDES; TRANSPLANTATION, HETEROLOGOUS; UP-REGULATION;

EID: 84902956076     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150611013     Document Type: Article

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