Bortezomib treatment causes long-term testicular dysfunction in young male mice

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Hou, Mi ^a   Eriksson, Emma ^a   Svechnikov, Konstantin ^a   Jahnukainen, Kirsi ^a,b   Söder, Olle ^a   Meinhardt, Andreas ^c   Sävendahl, Lars ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF HELSINKI   (Finland)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Bortezomib; Cancer; Mouse; Proteasome inhibitor; Testis

Indexed keywords

BORTEZOMIB; CASPASE 3; CASPASE 8; FOLLITROPIN; PROTEIN P53; TESTOSTERONE; BORONIC ACID DERIVATIVE; PROTEASOME INHIBITOR; PYRAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; ELECTRON MICROSCOPY; FEMALE; FOLLITROPIN BLOOD LEVEL; GERM CELL; HYPOSPERMATOGENESIS; LONG TERM EXPOSURE; MALE; MALE FERTILITY; MATING; MORPHOLOGY; MOUSE; NONHUMAN; POSTNATAL CARE; PROGENY; PROTEIN EXPRESSION; REPRODUCTION; SEMINIFEROUS TUBULE; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON DENSITY; TESTICULAR DYSFUNCTION; TESTIS FUNCTION; TESTIS INJURY; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; HUMAN; NEOPLASMS; PATHOLOGY; TESTIS; TESTIS DISEASE;

MUS;

ANIMALS; BORONIC ACIDS; FOLLICLE STIMULATING HORMONE; HUMANS; MALE; MICE; NEOPLASMS; PROTEASOME INHIBITORS; PYRAZINES; SPERMATOGENESIS; TESTICULAR DISEASES; TESTIS; TESTOSTERONE;

EID: 84902756908     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-155     Document Type: Article

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