Increasing effect of Tangzhiqing formula on IRS-1-dependent PI3K/AKT signaling in muscle

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Gao, Jing ^a   Li, Jian ^a   An, Yating ^a   Liu, Xuefeng ^a   Qian, Qian ^a   Wu, Yanlin ^a   Zhang, Yi ^a   Wang, Tao ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Crataegus pinnatifida; Insulin resistance; IRS 1 dependent PI3K signaling pathway; Morus alba; Nelumbo nucifera; Paeonia lactiflora; Salvia miltiorrhiza

Indexed keywords

CHINESE DRUG; GLUCOSE TRANSPORTER 4; GLYCOGEN SYNTHASE; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PAEONIA RADIX; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ROSIGLITAZONE; TANGZHIQING FORMULA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRATAEGUS; DISSECTION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; GLUCOSE METABOLISM; LIVER; LOTUS; MALE; MULBERRY; MUSCLE; MYOTUBE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 4; GLYCOGEN SYNTHASE; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN RECEPTOR SUBSTRATE PROTEINS; LIVER; MALE; MICE; MICE, INBRED C57BL; MUSCLES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 84902720140     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-198     Document Type: Article

References (24)

1. DeFronzo RA, Tripathy D. Skeletal muscle insulin resistance is the primary defect in type 2 diabetes. Diabetes Care 2009, 32(Suppl 2):S157-S163.
2. Hardie DG. Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism. Proc Nutr Soc 2010, 70(1):92-99.
3. Farese RV. Insulin-sensitive phospholipid signaling systems and glucose transport. Update II. Exp Biol Med (Maywood) 2001, 226(4):283-295.
4. Maiese K. Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus. Biomed Pharmacother 2008, 62(4):218-232.
5. Krook A, Wallberg-Henriksson H, Zierath JR. Sending the signal: molecular mechanisms regulating glucose uptake. Med Sci Sports Exerc 2004, 36(7):1212-1217.
6. Ooms LM, Horan KA, Rahman P, Seaton G, Gurung R, Kethesparan DS, Mitchell CA. The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease. Biochem J 2009, 419(1):29-49.
7. Lee JY, Kim YR, Park J, Kim S. Inositol polyphosphate multikinase signaling in the regulation of metabolism. Ann N Y Acad Sci 2012, 1271:68-74.
8. Khan KH, Yap TA, Yan L, Cunningham D. Targeting the PI3K-AKT-mTOR signaling network in cancer. Chin J Cancer 2013, 32(5):253-265.
9. Farese RV, Sajan MP, Standaert ML. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes. Exp Biol Med (Maywood) 2005, 230(9):593-605.
10. Rommel C, Camps M, Ji H. PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?. Nat Rev Immunol 2007, 7(3):191-201.
11. Tao W, Deqin Z, Yuhong L, Hong L, Zhanbiao L, Chunfeng Z, Limin H, Xiumei G. Regulation effects on abnormal glucose and lipid metabolism of TZQ-F, a new kind of Traditional Chinese Medicine. J Ethnopharmacol 2010, 128(3):575-582.
12. An YT, Liu XF, Qian Q, Zhang DQ, Li YH, Gao XM, Zhang Y, Wang T. Triglyceride accumulation: inhibitory effects of Tangzhiqing formula. Altern Ther Health M 2013, 19(4):58-69.
13. Thompson AM, Zhang Y, Tong W, Xu T, Chen J, Zhao L, Kelly TN, Chen CS, Bazzano LA, He J. Association of inflammation and endothelial dysfunction with metabolic syndrome, prediabetes and diabetes in adults from Inner Mongolia, China. BMC Endocr Disord 2011, 11:16.
14. Ortmeyer HK. Insulin decreases skeletal muscle cAMP-dependent protein kinase (PKA) activity in normal monkeys and increases PKA activity in insulin-resistant rhesus monkeys. J Basic Clin Physiol Pharmacol 1997, 8(4):223-235.
15. Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, Farese RV. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Diabetes 2002, 51(10):2936-2943.
16. Yang C, Chang TJ, Chang JC, Liu MW, Tai TY, Hsu WH, Chuang LM. Rosiglitazone (BRL 49653) enhances insulin secretory response via phosphatidylinositol 3-kinase pathway. Diabetes 2001, 50(11):2598-2602.
17. Patel NG, Holder JC, Smith SA, Kumar S, Eggo MC. Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation. Diabetes 2003, 52(1):43-50.
18. Kong WJ, Zhang H, Song DQ, Xue R, Zhao W, Wei J, Wang YM, Shan N, Zhou ZX, Yang P, You XF, Li ZR, Si SY, Zhao LX, Pan HN, Jiang JD. Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. Metabolism 2009, 58(1):109-119.
19. Altomare DA, Khaled AR. Homeostasis and the importance for a balance between AKT/mTOR activity and intracellular signaling. Curr Med Chem 2012, 19(22):3748-3762.
20. Konishi H, Shinomura T, Kuroda S, Ono Y, Kikkawa U. Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta. Biochem Biophys Res Commun 1994, 205(1):817-825.
21. Ortmeyer HK, Sajan MP, Miura A, Kanoh Y, Rivas J, Li Y, Standaert ML, Ryan AS, Bodkin NL, Farese RV, Hansen BC. Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C. Antioxid Redox Signal 2010, 14(2):207-219.
22. Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV, Farese RV. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states. J Biol Chem 2004, 279(24):24929-24934.
23. Franke TF. PI3K/Akt: getting it right matters. Oncogene 2008, 27(50):6473-6488.
24. Kim JK, Zisman A, Fillmore JJ, Peroni OD, Kotani K, Perret P, Zong H, Dong J, Kahn CR, Kahn BB, Shulman GI. Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4. J Clin Invest 2001, 108(1):153-160.