Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism

Science

Volumn 344, Issue 6189, 2014, Pages 1275-1279

  Xu, Kai ^a   Wu, Zhuhao ^b   Renier, Nicolas ^b   Antipenko, Alexander ^a   Tzvetkova Robev, Dorothea ^a   Xu, Yan ^a   Minchenko, Maria ^a   Nardi Dei, Vincenzo ^a,d   Rajashankar, Kanagalaghatta R ^c   Himanen, Juha ^a   Tessier Lavigne, Marc ^b   Nikolov, Dimitar B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c Department of Chemistry and Chemical Biology Cornell University Northeastern Collaborative Access Team ^*  (United States)

^d NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; LIGAND; NEOGENIN; NETRIN 1; CELL SURFACE RECEPTOR; DCC PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE GROWTH FACTOR; NETRIN RECEPTORS; NETRIN-1; TUMOR SUPPRESSOR PROTEIN;

LIGAND; SIGNAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCHITECTURE; ARTICLE; BINDING SITE; COLORECTAL CANCER; CONTROLLED STUDY; EMBRYO; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR BINDING; ANIMAL; C57BL MOUSE; CELL MOTION; CHEMISTRY; GENETICS; MUTANT MOUSE STRAIN; NERVE CELL; PHYSIOLOGY; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE;

ANIMALS; AXONS; CELL MOVEMENT; FIBRONECTINS; LIGANDS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NERVE GROWTH FACTORS; NEURONS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; TUMOR SUPPRESSOR PROTEINS;

EID: 84902688164     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1255149     Document Type: Article

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