Determinants of laminin polymerization revealed by the structure of the Î ±5 chain amino-terminal region

EMBO Reports

Volumn 12, Issue 3, 2011, Pages 276-282

  Hussain, Sadaf Ahmahni ^a   Carafoli, Federico ^a   Hohenester, Erhard ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

basement membrane; LN domain; netrin; X ray crystallography

Indexed keywords

EPIDERMAL GROWTH FACTOR; LAMININ;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; BASEMENT MEMBRANE; CRYSTAL STRUCTURE; CRYSTALLIZATION; FLOWER HEAD; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; SURFACE PROPERTY;

AMINO ACID SEQUENCE; ANIMALS; BASEMENT MEMBRANE; BINDING SITES; LAMININ; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYMERIZATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

EID: 79952279825     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2011.3     Document Type: Article

References (25)

1. Aumailley M et al (2005) A simplified laminin nomenclature. Matrix Biol 24: 326-332 (Pubitemid 41021635)
2. Boraston AB, Bolam DN, Gilbert HJ, Davies GJ (2004) Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J 382: 769-781 (Pubitemid 39312891)
3. Brünger AT et al (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54: 905-921
4. Carafoli F, Clout NJ, Hohenester E (2009) Crystal structure of the LG1-3 region of the laminin a2 chain. J Biol Chem 284: 22786-22792
5. CCP4 (1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 50: 760-763
6. Cheng YS, Champliaud MF, Burgeson RE, Marinkovich MP, Yurchenco PD (1997) Self-assembly of laminin isoforms. J Biol Chem 272: 31525-31532 (Pubitemid 28013294)
7. Dickson BJ (2002) Molecular mechanisms of axon guidance. Science 298: 1959-1964 (Pubitemid 35425245)
8. Edwards MM et al (2010) Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation. J Biol Chem 285: 7697-7711
9. Ettner N, Göhring W, Sasaki T, Mann K, Timpl R (1998) The N-terminal globular domain of the laminin a1 chain binds to a1b1 and a2b1 integrins and to the heparan sulfate-containing domains of perlecan. FEBS Lett 430: 217-221 (Pubitemid 28337916)
10. Garbe JH, Göhring W, Mann K, Timpl R, Sasaki T (2002) Complete sequence, Recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin a3B and a5 chains. Biochem J 362: 213-221 (Pubitemid 34174478)
11. Holm L, Rosenström P (2010) Dali server: conservation mapping in 3D. Nucleic Acids Res 38: W545-W549
12. Jones TA, Zou JY, Cowan SW, Kjeldgaard M (1991) Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A 47: 110-119
13. Kalkhof S, Haehn S, Paulsson M, Smyth N, Meiler J, Sinz A (2010) Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking. Proteins 78: 3409-3427
14. McKee KK, Harrison D, Capizzi S, Yurchenco PD (2007) Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem 282: 21437-21447 (Pubitemid 47099937)
15. Miner JH, Yurchenco PD (2004) Laminin functions in tissue morphogenesis. Annu Rev Cell Dev Biol 20: 255-284 (Pubitemid 39488639)
16. Nielsen PK, Yamada Y (2001) Identification of cell-binding sites on the Laminin a5 N-terminal domain by site-directed mutagenesis. J Biol Chem 276: 10906-10912 (Pubitemid 38089268)
17. Odenthal U, Haehn S, Tunggal P, Merkl B, Schomburg D, Frie C, Paulsson M, Smyth N (2004) Molecular analysis of laminin N-terminal domains mediating self-interactions. J Biol Chem 279: 44504-44512 (Pubitemid 39430857)
18. Patton BL, Wang B, Tarumi YS, Seburn KL, Burgess RW (2008) A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination. J Cell Sci 121: 1593-1604 (Pubitemid 351911816)
19. 2+ binding in the self-aggregation of laminin-nidogen complexes. J Biol Chem 263: 5425-5430
20. Stetefeld J, Mayer U, Timpl R, Huber R (1996) Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) Modules of laminin g1 chain harboring the nidogen binding site. J Mol Biol 257: 644-657 (Pubitemid 26107227)
21. Vonrhein C, Blanc E, Roversi P, Bricogne G (2007) Automated structure solution with autoSHARP. Methods Mol Biol 364: 215-230 (Pubitemid 350183137)
22. Xu H, Wu XR, Wewer UM, Engvall E (1994) Murine muscular dystrophy caused by A mutation in the laminin a2 (Lama2) Gene. Nat Genet 8: 297-302 (Pubitemid 24338744)
23. Yurchenco PD, Cheng YS (1993) Self-assembly and calcium-binding sites in laminin. A three-arm interaction model. J Biol Chem 268: 17286-17299 (Pubitemid 23236966)
24. Yurchenco PD, Tsilibary EC, Charonis AS, Furthmayr H (1985) Laminin polymerization in vitro. Evidence for A two-step assembly with domain specificity. J Biol Chem 260: 7636-7644 (Pubitemid 15063049)
25. Yurchenco PD, Amenta PS, Patton BL (2004) Basement membrane assembly, Stability and activities observed through A developmental lens. Matrix Biol 22: 521-538 (Pubitemid 38283776)