Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 12, 2014, Pages

  Stødkilde, Lene ^a   Palmfeldt, Johan ^a   Nilsson, Line ^a   Carlsen, Inge ^a   Wang, Yan ^a   Nørregaard, Rikke ^a   Frøkiær, Jørgen ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Acute proteome changes; Mass spectrometry; Ureteral obstruction

Indexed keywords

ACTIN BINDING PROTEIN; BETA ACTIN; BETA TUBULIN; COFILIN; INTERMEDIATE FILAMENT PROTEIN; REGULATOR PROTEIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; IMMUNOHISTOCHEMISTRY; KIDNEY INJURY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OBSTRUCTIVE UROPATHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; RAT; REGULATORY MECHANISM; URETER OBSTRUCTION; WESTERN BLOTTING;

ACUTE PROTEOME CHANGES; MASS SPECTROMETRY; URETERAL OBSTRUCTION;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; BIOMECHANICAL PHENOMENA; CYTOSKELETON; DISEASE MODELS, ANIMAL; KIDNEY; MALE; PROTEOMICS; RATS; RATS, WISTAR; TUBULIN; URETERAL OBSTRUCTION; VIMENTIN;

EID: 84902675176     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00244.2013     Document Type: Article

References (51)

1. Abbate M, Bonventre JV, Brown D. The microtubule network of renal epithelial cells is disrupted by ischemia and reperfusion. Am J Physiol Renal Fluid Electrolyte Physiol 267: F971-F978, 1994.
2. Ashworth S, Teng B, Kaufeld J, Miller E, Tossidou I, Englert C, Bollig F, Staggs L, Roberts IS, Park JK, Haller H, Schiffer M. Cofilin-1 inactivation leads to proteinuria-studies in zebrafish, mice and humans. PLoS One 5: e12626, 2010.
3. Baiges I, Palmfeldt J, Blade C, Gregersen N, Arola L. Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet. Mol Cell Proteomics 9: 1499-1513, 2010.
4. Bordier C. Phase separation of integral membrane proteins in Triton X-114 solution. J Biol Chem 256: 1604-1607, 1981.
5. Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA. Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. J Cell Biol 173: 733-741, 2006.
6. Broadbelt NV, Stahl PJ, Chen J, Mizrahi M, Lal A, Bozkurt A, Poppas DP, Felsen D. Early upregulation of iNOS mRNA expression and increase in NO metabolites in pressurized renal epithelial cells. Am J Physiol Renal Physiol 293: F1877-F1888, 2007.
7. Carlsen I, Donohue KE, Jensen AM, Selzer AL, Chen J, Poppas DP, Felsen D, Frøkiær J, Nørregaard R. Increased cyclooxygenase-2 expression and prostaglandin E2 production in pressurized renal medullary interstitial cells. Am J Physiol Regul Integr Comp Physiol 299: R823-R831, 2010.
8. Carlsen I, Nilsson L, Frokiaer J, Norregaard R. Changes in phosphorylated heat-shock protein 27 in response to acute ureteral obstruction in rats. Acta Physiol (Oxf) 209: 167-178, 2013.
9. Caron A, Desrosiers RR, Beliveau R. Kidney ischemia-reperfusion regulates expression and distribution of tubulin subunits, beta-actin and rho GTPases in proximal tubules. Arch Biochem Biophys 431: 31-46, 2004.
10. Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol 24: 1435-1450, 2013.
11. Chou SY, Cai H, Pai D, Mansour M, Huynh P. Regional expression of cyclooxygenase isoforms in the rat kidney in complete unilateral ureteral obstruction. J Urol 170: 1403-1408, 2003.
12. Cutroneo G, Arena S, Anastasi G, Cervellione RM, Grimaldi S, Di MD, Speciale F, Arena F, Di B, V, Favaloro A, Magno C. Altered cytoskeletal structure of smooth muscle cells in ureteropelvic junction obstruction. J Urol 185: 2314-2319, 2011.
13. Dos Remedios CG, Chhabra D, Kekic M, Dedova IV, Tsubakihara M, Berry DA, Nosworthy NJ. Actin binding proteins: regulation of cytoskeletal microfilaments. Physiol Rev 83: 433-473, 2003.
14. Frøkiær J, Marples D, Knepper M, Nielsen S. Bilateral ureteral obstruction downregulates expression of the vasopressin sensitive aquaporin-2 water channel in rat kidney. Am J Physiol Renal Fluid Electrolyte Physiol 270: F657-F668, 1996.
15. Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science 279: 514-519, 1998.
16. Gottschalk CW, Mylle M. Micropuncture study of pressures in proximal tubules and peritubular capillaries of the rat kidney and their relation to ureteral and renal venous pressures. Am J Physiol 185: 430-439, 1956.
17. Hamm-Alvarez SF, Sheetz MP. Microtubule-dependent vesicle transport: modulation of channel and transporter activity in liver and kidney. Physiol Rev 78: 1109-1129, 1998.
18. Hasler U, Mordasini D, Bens M, Bianchi M, Cluzeaud F, Rousselot M, Vandewalle A, Feraille E, Martin PY. Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells. J Biol Chem 277: 10379-10386, 2002.
19. Hsu CH, Kurtz TW, Rosenzweig J, Weller JM. Intrarenal hemodynamics and ureteral pressure during ureteral obstruction. Invest Urol 14: 442-445, 1977.
20. Huang dW, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13, 2009.
21. Huang dW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57, 2009.
22. Klahr S, Harris K, Purkerson ML. Effects of obstruction on renal functions. Pediatr Nephrol 2: 34-42, 1988.
23. Klein J, Gonzalez J, Miravete M, Caubet C, Chaaya R, Decramer S, Bandin F, Bascands JL, Buffin-Meyer B, Schanstra JP. Congenital ureteropelvic junction obstruction: human disease and animal models. Int J Exp Pathol 92: 168-192, 2011.
24. Lange-Sperandio B, Trautmann A, Eickelberg O, Jayachandran A, Oberle S, Schmidutz F, Rodenbeck B, Homme M, Horuk R, Schaefer F. Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol 171: 861-871, 2007.
25. Li C, Wang W, Kwon TH, Knepper MA, Nielsen S, Frøkiær J. Altered expression of major renal Na transporters in rats with bilateral ureteral obstruction and release of obstruction. Am J Physiol Renal Physiol 285: F889-F901, 2003.
26. Liapis H. Biology of congenital obstructive nephropathy. Nephron Exp Nephrol 93: e87-e91, 2003.
27. Lin KC, Krieg RJ Jr, Saborio P, Chan JC. Increased heat shock protein-70 in unilateral ureteral obstruction in rats. Mol Genet Metab 65: 303-310, 1998.
28. Masaki T, Foti R, Hill PA, Ikezumi Y, Atkins RC, Nikolic-Paterson DJ. Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney. Kidney Int 63: 1256-1264, 2003.
29. Mi H, Muruganujan A, Thomas PD. PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees. Nucleic Acids Res 41: D377-D386, 2013.
30. Molitoris BA. Ischemia-induced loss of epithelial polarity: potential role of the actin cytoskeleton. Am J Physiol Renal Fluid Electrolyte Physiol 260: F769-F778, 1991.
31. +-ATPase during ischemia. Am J Physiol Renal Fluid Electrolyte Physiol 263: F488-F495, 1992.
32. Murer L, Benetti E, Centi S, Della VM, Artifoni L, Capizzi A, Zucchetta P, Del PD, Carasi C, Montini G, Rigamonti W, Zaccello G. Clinical and molecular markers of chronic interstitial nephropathy in congenital unilateral ureteropelvic junction obstruction. J Urol 176: 2668-2673, 2006.
33. Nielsen J, Hoffert JD, Knepper MA, Agre P, Nielsen S, Fenton RA. Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: mechanisms for aquaporin 2 down-regulation and cellular proliferation. Proc Natl Acad Sci USA 105: 3634-3639, 2008.
34. Nilsson L, Madsen K, Topcu SO, Jensen BL, Frøkiær J, Nørregaard R. Disruption of cyclooxygenase-2 prevents downregulation of cortical AQP2 and AQP3 in response to bilateral ureteral obstruction in the mouse. Am J Physiol Renal Physiol 302: F1430-F1439, 2012.
35. Nørregaard R, Jensen BL, Li C, Wang W, Knepper MA, Nielsen S, Frøkiær J. COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction. Am J Physiol Renal Physiol 289: F322-F333, 2005.
36. Norregaard R, Jensen BL, Topcu SO, Nielsen SS, Walter S, Djurhuus JC, Frøkiær J. Cyclooxygenase type 2 is increased in obstructed rat and human ureter and contributes to pelvic pressure increase after obstruction. Kidney Int 70: 872-881, 2006.
37. Oliveros Venny JC. An interactive tool for comparing lists with Venn Diagrams. 2007.
38. Palmfeldt J, Vang S, Stenbroen V, Pedersen CB, Christensen JH, Bross P, Gregersen N. Mitochondrial proteomics on human fibroblasts for identification of metabolic imbalance and cellular stress. Proteome Sci 7: 20, 2009.
39. Peters CA. Animal models of fetal renal disease. Prenat Diagn 21: 917-923, 2001.
40. Ramaekers FC, Bosman FT. The cytoskeleton and disease. J Pathol 204: 351-354, 2004.
41. Ricardo SD, Ding G, Eufemio M, Diamond JR. Antioxidant expression in experimental hydronephrosis: role of mechanical stretch and growth factors. Am J Physiol Renal Physiol 272: F789-F798, 1997.
42. Rodriguez-Pena AB, Grande MT, Eleno N, Arevalo M, Guerrero C, Santos E, Lopez-Novoa JM. Activation of Erk1/2 and Akt following unilateral ureteral obstruction. Kidney Int 74: 196-209, 2008.
43. Silverstein DM, Travis BR, Thornhill BA, Schurr JS, Kolls JK, Leung JC, Chevalier RL. Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. Kidney Int 64: 25-35, 2003.
44. Solez K. The pathology and pathogenesis of human acute renal failure. In: Acute Renal Failure: Correlations Between Morphology and Function, edited by Solez K. New York and Basel: Dekker, 1984, p. 17-42.
45. Stodkilde L, Madsen MG, Palmfeldt J, Topcu SO, Norregaard R, Olsen LH, Jorgensen TM, Frøkiær J. Urinary proteome analysis in congenital bilateral hydronephrosis. Scand J Urol 47: 43-51, 2013.
46. Stodkilde L, Nørregaard R, Fenton RA, Wang G, Knepper MA, Frøkiær J. Bilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2. Am J Physiol Renal Physiol 301: F226-F235, 2011.
47. Thongboonkerd V. Proteomics in nephrology: current status and future directions. Am J Nephrol 24: 360-378, 2004.
48. Thongboonkerd V. Study of diabetic nephropathy in the proteomic era. Contrib Nephrol 170: 172-183, 2011.
49. Thongboonkerd V, Chutipongtanate S, Kanlaya R, Songtawee N, Sinchaikul S, Parichatikanond P, Chen ST, Malasit P. Proteomic identification of alterations in metabolic enzymes and signaling proteins in hypokalemic nephropathy. Proteomics 6: 2273-2285, 2006.
50. Valles P, Jorro F, Carrizo L, Manucha W, Oliva J, Cuello-Carrion FD, Ciocca DR. Heat shock proteins HSP27 and HSP70 in unilateral obstructed kidneys. Pediatr Nephrol 18: 527-535, 2003.
51. Woo DD, Miao SY, Pelayo JC, Woolf AS. Taxol inhibits progression of congenital polycystic kidney disease. Nature 368: 750-753, 1994.