Increased cyclooxygenase-2 expression and prostaglandin E2 production in pressurized renal medullary interstitial cells

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 299, Issue 3, 2010, Pages

  Carlsen, Inge ^a,b   Donohue, Kaitlin E ^c   Jensen, Anja M ^a,b   Selzer, Angela L ^c   Chen, Jie ^c   Poppas, Dix P ^c   Felsen, Diane ^c   Frøkiær, Jørgen ^a,b   Nørregaard, Rikke ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

Inner medulla; Interleukin 1 ; p38 MAPK; Parecoxib; Ureteral obstruction; Urethral obstruction

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; CYCLOOXYGENASE 2 INHIBITOR; INTERLEUKIN 1BETA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE INDUCTION; IN VIVO STUDY; INFLAMMATION; KIDNEY INTERSTITIUM; KIDNEY MEDULLA; MALE; MECHANICAL STRESS; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOTIC STRESS; PRESSURE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; URETER OBSTRUCTION; ANIMAL; CELL CULTURE; CELL DEATH; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SERUM; TIME;

ANIMALS; CELL DEATH; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; GENE EXPRESSION REGULATION; INTERLEUKIN-1BETA; KIDNEY MEDULLA; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PRESSURE; RATS; RNA, MESSENGER; SERUM; TIME FACTORS; URETERAL OBSTRUCTION;

EID: 77956685330     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00544.2009     Document Type: Article

References (33)

1. Akai Y, Homma T, Burns KD, Yasuda T, Badr KF, Harris RC. Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase. Am J Physiol Cell Physiol 267: C482-C490, 1994. (Pubitemid 24271082)
2. 2 through cAMP. Mediators Inflamm 8: 287-294, 1999.
3. 2 production by IFN-γ in human macrophages. J Immunol 161: 2441-2448, 1998.
4. Broadbelt NV, Stahl PJ, Chen J, Mizrahi M, Lal A, Bozkurt A, Poppas DP, Felsen D. Early upregulation of iNOS mRNA expression and increase in NO metabolites in pressurized renal epithelial cells. Am J Physiol Renal Physiol 293: F1877-F1888, 2007.
5. Campean V, Theilig F, Paliege A, Breyer M, Bachmann S. Key enzymes for renal prostaglandin synthesis: site-specific expression in rodent kidney (rat, mouse). Am J Physiol Renal Physiol 285: F19-F32, 2003.
6. Chen CF, Yeh SU, Chien CT, Wu MS. Renal response during acute unilateral ureteral obstruction in rats. Neurourol Urodyn 20: 125-137, 2001. (Pubitemid 32096334)
7. Chou SY, Cai H, Pai D, Mansour M, Huynh P. Regional expression of cyclooxygenase isoforms in the rat kidney in complete unilateral ureteral obstruction. J Urol 170: 1403-1408, 2003. (Pubitemid 37108171)
8. Dinarello CA. Biologic basis for interleukin-1β in disease. Blood 87: 2095-2147, 1996.
9. Felsen D, Schulsinger D, Gross SS, Kim FY, Marion D, Vaughan ED Jr. Renal hemodynamic and ureteral pressure changes in response to ureteral obstruction: the role of nitric oxide. J Urol 169: 373-376, 2003. (Pubitemid 35461649)
10. Ferreri NR, An SJ, McGiff JC. Cyclooxygenase-2 expression and function in the medullary thick ascending limb. Am J Physiol Renal Physiol 277: F360-F368, 1999. (Pubitemid 29459648)
11. Fitzgerald JB, Jin M, Dean D, Wood DJ, Zheng MH, Grodzinsky AJ. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem 279: 19502-19511, 2004. (Pubitemid 38623385)
12. Fontoura BM, Nussenzveig DR, Pelton KM, Maack T. Atrial natriuretic factor receptors in cultured renomedullary interstitial cells. Am J Physiol Cell Physiol 258: C692-C699, 1990. (Pubitemid 20140654)
13. Hao CM, Komhoff M, Guan Y, Redha R, Breyer MD. Selective targeting of cyclooxygenase-2 reveals its role in renal medullary interstitial cell survival. Am J Physiol Renal Physiol 277: F352-F359, 1999. (Pubitemid 29459647)
14. Hao CM, Yull F, Blackwell T, Komhoff M, Davis LS, Breyer MD. Dehydration activates an NF-κB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells. J Clin Invest 106: 973-982, 2000.
15. Inoue H, Taba Y, Miwa Y, Yokota C, Miyagi M, Sasaguri T. Transcriptional and posttranscriptional regulation of cyclooxygenase-2 expression by fluid shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 22: 1415-1420, 2002.
16. Jerde TJ, Mellon WS, Bjorling DE, Nakada SY. Evaluation of urothelial stretch-induced cyclooxygenase-2 expression in novel human cell culture and porcine in vivo ureteral obstruction models. J Pharmacol Exp Ther 317: 965-972, 2006.
17. Jerde TJ, Mellon WS, Checura CM, Parrish JJ, Owusu-Ofori K, Bjorling DE, Nakada SY. Stretch induction of cyclooxygenase-2 expression in human urothelial cells is calcium and protein kinase C zeta-dependent. Mol Pharmacol 2007.
18. Ju WK, Kim KY, Lindsey JD, Angert M, Patel A, Scott RT, Liu Q, Crowston JG, Ellisman MH, Perkins GA, Weinreb RN. Elevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells. Mol Vis 15: 120-134, 2009.
19. Maric C, Aldred GP, Antoine AM, Dean RG, Eitle E, Mendelsohn FA, Williams DA, Harris PJ, Alcorn D. Effects of angiotensin II on cultured rat renomedullary interstitial cells are mediated by AT1A receptors. Am J Physiol Renal Fluid Electrolyte Physiol 271: F1020-F1028, 1996.
20. Martineau LC, McVeigh LI, Jasmin BJ, Kennedy CR. p38 MAP kinase mediates mechanically induced COX-2 and PG EP4 receptor expression in podocytes: implications for the actin cytoskeleton. Am J Physiol Renal Physiol 286: F693-F701, 2004.
21. Noguchi K, Shitashige M, Endo H, Kondo H, Yotsumoto Y, Izumi Y, Nitta H, Ishikawa I. Involvement of cyclooxygenase-2 in serum-induced prostaglandin production by human oral gingival epithelial cells. J Periodontal Res 36: 124-130, 2001. (Pubitemid 33636985)
22. Norregaard R, Jensen BL, Li C, Wang W, Knepper MA, Nielsen S, Frokiaer J. COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction. Am J Physiol Renal Physiol 289: F322-F333, 2005. (Pubitemid 41003662)
23. Norregaard R, Jensen BL, Topcu SO, Nielsen SS, Walter S, Djurhuus JC, Frokiaer J. Cyclooxygenase type 2 is increased in obstructed rat and human ureter and contributes to pelvic pressure increase after obstruction. Kidney Int 70: 872-881, 2006. (Pubitemid 44285964)
24. Okegawa T, Jonas PE, DeSchryver K, Kawasaki A, Needleman P. Metabolic and cellular alterations underlying the exaggerated renal prostaglandin and thromboxane synthesis in ureter obstruction in rabbits. Inflammatory response involving fibroblasts and mononuclear cells. J Clin Invest 71: 81-90, 1983. (Pubitemid 13170240)
25. Parente L, Perretti M. Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight. Biochem Pharmacol 65: 153-159, 2003. (Pubitemid 36015818)
26. Park JM, Yang T, Arend LJ, Schnermann JB, Peters CA, Freeman MR, Briggs JP. Obstruction stimulates COX-2 expression in bladder smooth muscle cells via increased mechanical stretch. Am J Physiol Renal Physiol 276: F129-F136, 1999. (Pubitemid 29061733)
27. Persson AE, Wahlberg J, Safirstein R, Wright FS. The effect of 2 hours of complete unilateral ureteral obstruction on tubuloglomerular feedback control. Acta Physiol Scand 122: 35-43, 1984. (Pubitemid 14003856)
28. Pope JC, Showalter PR, Milam DF, Brock JW III. Intrapelvic pressure monitoring in the partially obstructed porcine kidney. Urology 44: 565-571, 1994.
29. Rao R, Hao CM, Breyer MD. Hypertonic stress activates glycogen synthase kinase 3β-mediated apoptosis of renal medullary interstitial cells, suppressing an NFκB-driven cyclooxygenase-2-dependent survival pathway. J Biol Chem 279: 3949-3955, 2004. (Pubitemid 38198978)
30. Sappington RM, Chan M, Calkins DJ. Interleukin-6 protects retinal ganglion cells from pressure-induced death. Invest Ophthalmol Vis Sci 47: 2932-2942, 2006. (Pubitemid 351639769)
31. Wadleigh DJ, Herschman HR. Transcriptional regulation of the cyclooxygenase- 2 gene by diverse ligands in murine osteoblasts. Biochem Biophys Res Commun 264: 865-870, 1999.
32. Xie W, Herschman HR. Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem 271: 31742-31748, 1996.
33. Yang T, Sun D, Huang YG, Smart A, Briggs JP, Schnermann JB. Differential regulation of COX-2 expression in the kidney by lipopolysaccharide: role of CD14. Am J Physiol Renal Physiol 277: F10-F16, 1999. (Pubitemid 29352669)