Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Sun, Jing Chuan ^a   Xu, Tao ^a   Zuo, Qiao ^a   Wang, Ruo Bing ^b   Qi, Ai Qing ^a   Cao, Wen Luo ^a   Sun, Ai Jun ^a   Sun, Xue Jun ^a   Xu, Jiajun ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SYNUCLEIN; HYDROGEN; MALONALDEHYDE; PLACEBO; SODIUM CHLORIDE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EVOKED VISUAL RESPONSE; MALE; NERVE CRUSH; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; PUPIL REFLEX; RAT; RETINA GANGLION CELL; ANIMAL; CELL COUNT; DISEASE MODEL; DRUG EFFECTS; LIGHT; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PUPIL; RADIATION RESPONSE; REFLEX; SPRAGUE DAWLEY RAT; STAINING; TUNEL ASSAY; VISUAL EVOKED POTENTIAL;

ANIMALS; CELL COUNT; CELL SURVIVAL; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS, VISUAL; GAMMA-SYNUCLEIN; HYDROGEN; IN SITU NICK-END LABELING; LIGHT; MALE; MALONDIALDEHYDE; NERVE CRUSH; OPTIC NERVE INJURIES; PUPIL; RATS, SPRAGUE-DAWLEY; REFLEX; RETINAL GANGLION CELLS; SODIUM CHLORIDE; STAINING AND LABELING;

EID: 84902670015     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099299     Document Type: Article

References (46)

1. Kanski JJ (2003) Clinical Ophthalmology. 5th ed. Philadelphia. Butterworth-Heinemann. 670 p.
2. Bien A, Seidenbecher CI, Bockers TM, Sabel BA, Kreutz MR (1999) Apoptotic versus necrotic characteristics of retinal ganglion cell death after partial optic nerve injury. J Neurotrauma 16: 153-163. (Pubitemid 29113826)
3. Kreutz MR, Seidenbecher CI, Sabel BA (1999) Molecular plasticity of retinal ganglion cells after partial optic nerve injury. Restor Neurol Neurosci 14: 127-134. (Pubitemid 29173193)
4. Coyle JT, Puttfarcken P (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695. (Pubitemid 23350687)
5. Clutton S (1997) The importance of oxidative stress in apoptosis. Br Med Bull 53: 662-668.
6. Levkovitch-Verbin H, Harris-Cerruti C, Groner Y, Wheeler LA, Schwartz M, et al. (2000) RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection. Invest Ophthalmol Vis Sci 41: 4169-4174.
7. Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, et al. (2007) Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13: 688-694. (Pubitemid 46889750)
8. Fukuda K, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, et al. (2007) Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. Biochem Biophys Res Commun 361: 670-674. (Pubitemid 47238041)
9. Zheng X, Mao Y, Cai J, Li Y, Liu W, et al. (2009) Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. Free Radic Res 43: 478-484.
10. Shingu C, Koga H, Hagiwara S, Matsumoto S, Goto K, et al. (2010) Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury. J Anesth 24: 569-574.
11. Wang F, Yu G, Liu SY, Li JB, Wang JF, et al. (2011) Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats. J Surg Res 167: e339-344.
12. Qian L, Cao F, Cui J, Huang Y, Zhou X, et al. (2010) Radioprotective effect of hydrogen in cultured cells and mice. Free Radic Res 44: 275-282.
13. Terasaki Y, Ohsawa I, Terasaki M, Takahashi M, Kunugi S, et al. (2011) Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. Am J Physiol Lung Cell Mol Physiol 301: L415-426.
14. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, et al. (2008) Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res 28: 137-143. (Pubitemid 351452069)
15. Li Y, Hamasaki T, Nakamichi N, Kashiwagi T, Komatsu T, et al. (2011) Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnology 63: 119-131.
16. Kajiya M, Silva MJ, Sato K, Ouhara K, Kawai T (2009) Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. Biochem Biophys Res Commun 386: 11-15.
17. Kajiya M, Sato K, Silva MJ, Ouhara K, Do PM, et al. (2009) Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis. Biochem Biophys Res Commun 386: 316-321.
18. Chen H, Sun YP, Li Y, Liu WW, Xiang HG, et al. (2010) Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. Biochem Biophys Res Commun 393: 308-313.
19. Zhao L, Zhou C, Zhang J, Gao F, Li B, et al. (2011) Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. Int J Biol Sci 7: 297-300.
20. Huang Y, Xie K, Li J, Xu N, Gong G, et al. (2011) Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. Brain Res 1378: 125-136.
21. Cai J, Kang Z, Liu WW, Luo X, Qiang S, et al. (2008) Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci Lett 441: 167-172.
22. Cai J, Kang Z, Liu K, Liu W, Li R, et al. (2009) Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res 1256: 129-137.
23. Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, et al. (2009) Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neurosci Lett 453: 81-85.
24. Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, et al. (2009) Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2, 3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One 4: e7247.
25. Li J, Wang C, Zhang JH, Cai JM, Cao YP, et al. (2010) Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Res 1328: 152-161.
26. Wang C, Li J, Liu Q, Yang R, Zhang JH, et al. (2011) Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-kappaB activation in a rat model of amyloid-beta-induced Alzheimer's disease. Neurosci Lett 491: 127-132.
27. Kikkawa YS, Nakagawa T, Horie RT, Ito J (2009) Hydrogen protects auditory hair cells from free radicals. Neuroreport 20: 689-694.
28. Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, et al. (2011) Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs. Neurosci Lett 487: 12-16.
29. Ji X, Liu W, Xie K, Liu W, Qu Y, et al. (2010) Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress. Brain Res 1354: 196-205.
30. Oharazawa H, Igarashi T, Yokota T, Fujii H, Suzuki H, et al. (2009) Rapid diffusion of hydrogen protects the retina: administration to the eye of hydrogen-containing saline in retinal ischemia-reperfusion injury. Invest Ophth Vis Sci iovs: 09-4089.
31. Wei L, Ge L, Qin S, Shi Y, Du C, et al. (2012) Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. Exp Eye Res 94: 117-127.
32. Wang R, Xu J, Xie J, Kang Z, Sun X, et al. (2010) Hyperbaric oxygen preconditioning promotes survival of retinal ganglion cells in a rat model of optic nerve crush. J Neurotrauma 27: 763-770.
33. Kilic U, Kilic E, Soliz J, Bassetti CI, Gassmann M, et al. (2005) Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J 19: 249-251. (Pubitemid 40189271)
34. Surgucheva I, Weisman AD, Goldberg JL, Shnyra A, Surguchov A (2008) Gamma-synuclein as a marker of retinal ganglion cells. Mol Vis 14: 1540-1548.
35. Chan KM, Young MJ, Lund RD (1995) Interactive events subserving the pupillary light reflex in pigmented and albino rats. Eur J Neurosci 7: 2053-2063.
36. Grozdanic S, Betts DM, Allbaugh RA, Sakaguchi DS, Kwon YH, et al. (2003) Characterization of the pupil light reflex, electroretinogram and tonometric parameters in healthy mouse eyes. Curr Eye Res 26: 371-378. (Pubitemid 36920839)
37. Chen J, Ou YX, Da WM, Kang JH (2004) Coadjustment of quercetin and hydrogen peroxide: the role of ROS in the cytotoxicity of quercetin. Pharmazie 59: 155-158. (Pubitemid 38222489)
38. Whiteley SJ, Sauve Y, Aviles-Trigueros M, Vidal-Sanz M, Lund RD (1998) Extent and duration of recovered pupillary light reflex following retinal ganglion cell axon regeneration through peripheral nerve grafts directed to the pretectum in adult rats. Exp Neurol 154: 560-572. (Pubitemid 29044225)
39. Wilhelm H, Wilhelm B (2003) Clinical applications of pupillography. J Neuroophthalmol 23: 42-49. (Pubitemid 36292815)
40. Demediuk P, Daly MP, Faden AI (1989) Changes in free fatty acids, phospholipids, and cholesterol following impact injury to the rat spinal cord. J Neurosci Res 23: 95-106. (Pubitemid 19167328)
41. Flamm ES, Demopoulos HB, Seligman ML, Poser RG, Ransohoff J (1978) Free radicals in cerebral ischemia. Stroke 9: 445-447. (Pubitemid 8389070)
42. Schori H, Yoles E, Schwartz M (2001) T-cell-based immunity counteracts the potential toxicity of glutamate in the central nervous system. J Neuroimmunol 119: 199-204. (Pubitemid 32918327)
43. Vorwerk CK, Zurakowski D, McDermott LM, Mawrin C, Dreyer EB (2004) Effects of axonal injury on ganglion cell survival and glutamate homeostasis. Brain Res Bull 62: 485-490. (Pubitemid 38253033)
44. Matteucci A, Frank C, Domenici MR, Balduzzi M, Paradisi S, et al. (2005) Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D: -aspartate-induced intracellular Ca(2+) increase. Exp Brain Res 167: 641-648.
45. Galindo-Romero C, Valiente-Soriano FJ, Jimenez-Lopez M, Garcia-Ayuso D, Villegas-Perez MP, et al. (2013) Effect of brain-derived neurotrophic factor on mouse axotomized retinal ganglion cells and phagocytic microglia. Invest Ophthalmol Vis Sci 54: 974-985.
46. Gallego BI, Salazar JJ, de Hoz R, Rojas B, Ramirez AI, et al. (2012) IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma. J Neuroinflammation 9: 92.