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Volumn 15, Issue 9, 2014, Pages 3939-3944

Rapamycin and PF4 induce apoptosis by upregulating bax and down-regulating survivin in MNU-induced breast cancer

Author keywords

Apoptosis; Bax; Bcl 2; Breast cancer; Rapamycin; Survivin

Indexed keywords

BIRC5 PROTEIN, RAT; METHYLNITROSOUREA; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN BAX; PROTEIN BCL 2; RAPAMYCIN; THROMBOCYTE FACTOR 4;

EID: 84902658833     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.9.3939     Document Type: Article
Times cited : (11)

References (34)
  • 1
    • 28244490602 scopus 로고    scopus 로고
    • Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
    • Asanuma H, Torigoe T, Kamiguchi K, et al (2005). Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. Cancer Res, 65, 11018-25.
    • (2005) Cancer Res , vol.65 , pp. 11018-110125
    • Asanuma, H.1    Torigoe, T.2    Kamiguchi, K.3
  • 2
    • 70449390905 scopus 로고    scopus 로고
    • Rapamycin and mTOR kinase inhibitors
    • Ballou LM, Lin RZ (2008). Rapamycin and mTOR kinase inhibitors. J Chem Biol, 1, 27-36.
    • (2008) J Chem Biol , vol.1 , pp. 27-36
    • Ballou, L.M.1    Lin, R.Z.2
  • 3
    • 70350057568 scopus 로고    scopus 로고
    • Apoptosis in cancer: key molecular signaling pathways and therapy targets
    • Burz C, Berindan-Neagoe I, Balacescu O, Irimie A (2009). Apoptosis in cancer: key molecular signaling pathways and therapy targets. Acta oncologica, 48, 811-21.
    • (2009) Acta oncologica , vol.48 , pp. 811-821
    • Burz, C.1    Berindan-Neagoe, I.2    Balacescu, O.3    Irimie, A.4
  • 4
    • 84902666716 scopus 로고    scopus 로고
    • GLOBOCAN 2008 (IARC), S. o. C. I, Section of Cancer Information (29/8/2013)
    • GLOBOCAN 2008 (IARC), S. o. C. I. (2008). Section of Cancer Information (29/8/2013)
    • (2008)
  • 5
    • 0016611429 scopus 로고
    • N-nitrosomethylurea as mammary gland carcinogen in rats
    • Gullino P, Pettigrew HM, Grantham F (1975). N-nitrosomethylurea as mammary gland carcinogen in rats. J Natl Cancer Inst, 54, 401-14.
    • (1975) J Natl Cancer Inst , vol.54 , pp. 401-414
    • Gullino, P.1    Pettigrew, H.M.2    Grantham, F.3
  • 6
    • 0031720975 scopus 로고    scopus 로고
    • Apoptosis in the mammary gland and breast cancer
    • Hahm H, Davidson N (1998). Apoptosis in the mammary gland and breast cancer. Endocrine-related cancer, 5, 199-211.
    • (1998) Endocrine-related cancer , vol.5 , pp. 199-211
    • Hahm, H.1    Davidson, N.2
  • 7
    • 84892458129 scopus 로고    scopus 로고
    • Oleuropein induces apoptosis via the p53 pathway in breast cancer cells
    • Hassan Z K, Elamin M H, Omer S A, et al (2013). Oleuropein induces apoptosis via the p53 pathway in breast cancer cells. Asian Pac J Cancer Prev, 14, 6739-42.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 6739-6742
    • Hassan, Z.K.1    Elamin, M.H.2    Omer, S.A.3
  • 8
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M O (2000). The biochemistry of apoptosis. Nature, 407, 770-76.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 9
    • 84856735270 scopus 로고    scopus 로고
    • Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway
    • Huang K, Huang Y, Diao Y (2012). Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway. Int Immunopharmacol, 12, 334-41.
    • (2012) Int Immunopharmacol , vol.12 , pp. 334-341
    • Huang, K.1    Huang, Y.2    Diao, Y.3
  • 10
    • 77954218447 scopus 로고    scopus 로고
    • Molecularly targeted therapy in hepatocellular carcinoma
    • Huynh H (2010). Molecularly targeted therapy in hepatocellular carcinoma. Biochemical Pharmacol, 80, 550-60.
    • (2010) Biochemical Pharmacol , vol.80 , pp. 550-560
    • Huynh, H.1
  • 11
    • 84873650167 scopus 로고    scopus 로고
    • Expression of Bax and Bcl-2 in tumour cells and blood vessels of breast cancer and their association with angiogenesis and hormonal receptors
    • Jaafar H, Abdullah S, Murtey M D, Idris F M (2012). Expression of Bax and Bcl-2 in tumour cells and blood vessels of breast cancer and their association with angiogenesis and hormonal receptors. Asian Pac J Cancer Prev, 13, 3857-62.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 3857-3862
    • Jaafar, H.1    Abdullah, S.2    Murtey, M.D.3    Idris, F.M.4
  • 12
    • 66649092039 scopus 로고    scopus 로고
    • The association between phenotype and size of breast tumors induced by 1-methyl-1-nitrosourea (MNU) injection in rats
    • Jaafar H, Idris F M, Nafi S N M (2009). The association between phenotype and size of breast tumors induced by 1-methyl-1-nitrosourea (MNU) injection in rats. Med Sci Monit, 15.
    • (2009) Med Sci Monit , pp. 15
    • Jaafar, H.1    Idris, F.M.2    Nafi, S.N.M.3
  • 13
    • 84860337543 scopus 로고    scopus 로고
    • Survivin expression and targeting in breast cancer
    • Jha K, Shukla M, Pandey M (2012). Survivin expression and targeting in breast cancer. Surgical Oncology, 21, 125-31.
    • (2012) Surgical Oncology , vol.21 , pp. 125-131
    • Jha, K.1    Shukla, M.2    Pandey, M.3
  • 14
    • 0032574761 scopus 로고    scopus 로고
    • Bax directly induces release of cytochrome c from isolated mitochondria
    • Jürgensmeier J M, Xie Z, Deveraux Q, et al (1998). Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA, 95, 4997-5002.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4997-5002
    • Jürgensmeier, J.M.1    Xie, Z.2    Deveraux, Q.3
  • 15
    • 63149119124 scopus 로고    scopus 로고
    • Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance
    • Lu J, Tan M, Huang WC, et al (2009). Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance. Clin Cancer Res, 15, 1326-34.
    • (2009) Clin Cancer Res , vol.15 , pp. 1326-1334
    • Lu, J.1    Tan, M.2    Huang, W.C.3
  • 16
    • 0025767622 scopus 로고
    • Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity
    • Maione T E, Gray G S, Hunt A J, Sharpe R J (1991). Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity. Cancer Res, 51, 2077-83.
    • (1991) Cancer Res , vol.51 , pp. 2077-2083
    • Maione, T.E.1    Gray, G.S.2    Hunt, A.J.3    Sharpe, R.J.4
  • 17
    • 33646388647 scopus 로고    scopus 로고
    • Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ
    • Namba R, Young L J, Abbey C K, et al (2006). Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ. Clinical Cancer Res, 12, 2613-21.
    • (2006) Clinical Cancer Res , vol.12 , pp. 2613-2621
    • Namba, R.1    Young, L.J.2    Abbey, C.K.3
  • 18
    • 1042267229 scopus 로고    scopus 로고
    • Determinants of rapamycin sensitivity in breast cancer cells
    • Noh WC, Mondesire W H, Peng J, et al (2004). Determinants of rapamycin sensitivity in breast cancer cells. Clinical Cancer Res, 10, 1013-23.
    • (2004) Clinical Cancer Res , vol.10 , pp. 1013-1023
    • Noh, W.C.1    Mondesire, W.H.2    Peng, J.3
  • 19
    • 74549223522 scopus 로고    scopus 로고
    • Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer
    • Purcell J W, Davis J, Reddy M, et al (2010). Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer. Clinical Cancer Res, 16, 566-76.
    • (2010) Clinical Cancer Res , vol.16 , pp. 566-576
    • Purcell, J.W.1    Davis, J.2    Reddy, M.3
  • 20
    • 0030162560 scopus 로고    scopus 로고
    • Balancing cell life and death: bax, apoptosis, and breast cancer
    • Reed J (1996). Balancing cell life and death: bax, apoptosis, and breast cancer. J Clin Invest, 97, 2403.
    • (1996) J Clin Invest , vol.97 , pp. 2403
    • Reed, J.1
  • 21
    • 0028954092 scopus 로고
    • The etiopathogenesis of breast cancer prevention
    • Russo J, Russo I H (1995). The etiopathogenesis of breast cancer prevention. Cancer letters, 90, 81-9.
    • (1995) Cancer letters , vol.90 , pp. 81-89
    • Russo, J.1    Russo, I.H.2
  • 22
    • 0034523249 scopus 로고    scopus 로고
    • Atlas and histologic classification of tumors of the rat mammary gland
    • Russo J, Russo I H (2000). Atlas and histologic classification of tumors of the rat mammary gland. J Mammary Gland Biol Neoplasia, 5, 187-200.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 187-200
    • Russo, J.1    Russo, I.H.2
  • 24
    • 77949484645 scopus 로고    scopus 로고
    • Rapamycin inhibits proliferation and migration of hepatoma cells
    • Shirouzu Y, Ryschich E, Salnikova O, et al (2010). Rapamycin inhibits proliferation and migration of hepatoma cells. J Surg Res, 159, 705-13.
    • (2010) J Surg Res , vol.159 , pp. 705-713
    • Shirouzu, Y.1    Ryschich, E.2    Salnikova, O.3
  • 25
    • 74849131091 scopus 로고    scopus 로고
    • Targeting mTOR globally in cancer: thinking beyond rapamycin
    • Shor B, Gibbons J J, Abraham R T, Yu K (2009). Targeting mTOR globally in cancer: thinking beyond rapamycin. Cell Cycle, 8, 3831-7.
    • (2009) Cell Cycle , vol.8 , pp. 3831-3837
    • Shor, B.1    Gibbons, J.J.2    Abraham, R.T.3    Yu, K.4
  • 26
    • 84876094075 scopus 로고    scopus 로고
    • Targeting apoptosis pathways in cancer stem cells
    • Signore M, Ricci-Vitiani L, De Maria R (2013). Targeting apoptosis pathways in cancer stem cells. Cancer letters, 332, 374-82.
    • (2013) Cancer letters , vol.332 , pp. 374-382
    • Signore, M.1    Ricci-Vitiani, L.2    De Maria, R.3
  • 28
    • 0033980409 scopus 로고    scopus 로고
    • Expression of survivin and its relationship to loss of apoptosis in breast carcinomas
    • Tanaka K, Iwamoto S, Gon G, et al (2000). Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clinical Cancer Res, 6, 127-34.
    • (2000) Clinical Cancer Res , vol.6 , pp. 127-134
    • Tanaka, K.1    Iwamoto, S.2    Gon, G.3
  • 29
    • 0028785824 scopus 로고
    • Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea
    • Thompson H J, McGinley J N, Rothhammer K, Singh M (1995). Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea. Carcinogenesis, 16, 2407-12.
    • (1995) Carcinogenesis , vol.16 , pp. 2407-2412
    • Thompson, H.J.1    McGinley, J.N.2    Rothhammer, K.3    Singh, M.4
  • 30
    • 0033923368 scopus 로고    scopus 로고
    • Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
    • Verdecia M A, Huang Hk, Dutil E, et al (2000). Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement. Nature Structural Molec Biol, 7, 602-8.
    • (2000) Nature Structural Molec Biol , vol.7 , pp. 602-608
    • Verdecia, M.A.1    Huang, H.K.2    Dutil, E.3
  • 31
    • 84894671172 scopus 로고    scopus 로고
    • Fangchinoline Inhibits cell proliferation via Akt/GSK-3beta/cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells
    • Wan L Z, Hu N, Liu XJ, et al (2014). Fangchinoline Inhibits cell proliferation via Akt/GSK-3beta/cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells. Asian Pac J Cancer Prev, 15, 769-73.
    • (2014) Asian Pac J Cancer Prev , vol.15 , pp. 769-773
    • Wan, L.Z.1    Hu, N.2    Liu, X.J.3
  • 33
    • 84893422460 scopus 로고    scopus 로고
    • Gambogenic acid induction of apoptosis in a breast cancer cell line
    • Zhou J, Luo YH, Wang JR, Lu BB, Tian Y (2013). Gambogenic acid induction of apoptosis in a breast cancer cell line. Asian Pac J Cancer Prev, 14, 7601-05.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 7601-7605
    • Zhou, J.1    Luo, Y.H.2    Wang, J.R.3    Lu, B.B.4    Tian, Y.5
  • 34
    • 6344291174 scopus 로고    scopus 로고
    • An alternatively spliced survivin variant is positively regulated by p53 and sensitizes leukemia cells to chemotherapy
    • Zhu N, Gu L, Findley H W, Li F, Zhou M (2004). An alternatively spliced survivin variant is positively regulated by p53 and sensitizes leukemia cells to chemotherapy. Oncogene, 23, 7545-51.
    • (2004) Oncogene , vol.23 , pp. 7545-7551
    • Zhu, N.1    Gu, L.2    Findley, H.W.3    Li, F.4    Zhou, M.5


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