Fangchinoline inhibits cell proliferation via Akt/GSK-3beta/cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 2, 2014, Pages 769-773

  Wang, Chang Dong ^a   Yuan, Cheng Fu ^a   Bu, You Quan ^a   Wu, Xiang Mei ^a   Wan, Jin Yuan ^b   Zhang, Li ^b   Hu, Ning ^c   Liu, Xian Jun ^a   Zu, Yong ^a   Liu, Ge Li ^a   Song, Fang Zhou ^a  

^a Chongqing Molecular Medicine and Cancer Research Center   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; CyclinD1; Fangchinoline; Proliferation

Indexed keywords

BENZYLISOQUINOLINE DERIVATIVE; CCND1 PROTEIN, HUMAN; CYCLIN D1; FANGQUINOLINE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MESSENGER RNA; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; BREAST TUMOR; CELL CYCLE; CELL PROLIFERATION; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; BENZYLISOQUINOLINES; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; CYCLIN D1; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; HUMANS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 84894671172     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.2.769     Document Type: Article

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