Pannexin-1 is blocked by its C-terminus through a delocalized non-specific interaction surface

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Dourado, Michelle ^a   Wong, Evera ^a   Hackos, David H ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; CASPASE; ION CHANNEL; PANNEXIN 1; UNCLASSIFIED DRUG; CASPASE 3; GAP JUNCTION PROTEIN; NERVE PROTEIN; PANX1 PROTEIN, HUMAN; PANX1 PROTEIN, MOUSE; PROTEIN BINDING;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MUTAGENESIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN DOMAIN; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CASPASE 3; CONNEXINS; GENE EXPRESSION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

EID: 84902593565     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099596     Document Type: Article

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