Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Delimont, Duane ^a   Dufek, Brianna M ^a   Meehan, Daniel T ^a   Zallocchi, Marisa ^a   Gratton, Michael Anne ^c   Phillips, Grady ^c   Cosgrove, Dominic ^a,b  

^a BOYS TOWN NATIONAL RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 CHLORO 2 (2 METHOXY 4 MORPHOLINOANILINO) 4 PYRIMIDINYLAMINO] N METHYLBENZAMIDE; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; GELATINASE B; INTERLEUKIN 6; LAMININ ALPHA2; MACROPHAGE ELASTASE; MESSENGER RNA; SMALL INTERFERING RNA; STROMELYSIN 2; CD151 ANTIGEN; I KAPPA B; LAMININ; LAMININ A; MATRIX METALLOPROTEINASE; MORPHOLINE DERIVATIVE; NF-KAPPAB INHIBITOR ALPHA; PROTEIN KINASE INHIBITOR;

ALPORT SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; FIBROSIS; GENE EXPRESSION; GENE SILENCING; GLOMERULOSCLEROSIS; GLOMERULUS BASEMENT MEMBRANE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PATHOGENESIS; PODOCYTE; PROTEIN EXPRESSION; PROTEINURIA; TISSUE INJURY; ULTRASTRUCTURE; UREA NITROGEN BLOOD LEVEL; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOMECHANICS; DRUG EFFECTS; ENZYMOLOGY; KINETICS; METABOLISM; NEPHRITIS, HEREDITARY; PATHOLOGY;

ANIMALS; ANTIGENS, CD151; BIOMECHANICAL PHENOMENA; CELLS, CULTURED; ENZYME ACTIVATION; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE KNOCKDOWN TECHNIQUES; GLOMERULAR BASEMENT MEMBRANE; I-KAPPA B PROTEINS; INTERLEUKIN-6; KINETICS; LAMININ; MATRIX METALLOPROTEINASES; MICE, KNOCKOUT; MORPHOLINES; NEPHRITIS, HEREDITARY; PODOCYTES; PROTEIN KINASE INHIBITORS; RNA, SMALL INTERFERING;

EID: 84902590772     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099083     Document Type: Article

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