SERCA2 dysfunction in darier disease causes endoplasmic reticulum stress and impaired cell-to-cell adhesion strength: Rescue by miglustat

Journal of Investigative Dermatology

Volumn 134, Issue 7, 2014, Pages 1961-1970

  Savignac, Magali ^a   Simon, Marina ^a,b,c   Edir, Anissa ^a,b   Guibbal, Laure ^a,b,c   Hovnanian, Alain ^a,b,c,d  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c IMAGINE INSTITUTE   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ALPHA CATENIN; BETA CATENIN; DESMOCOLLIN; DESMOCOLLIN 3; DESMOGLEIN 3; DESMOPLAKIN; DESMOSOMAL CADHERIN; DISPASE; MIGLUSTAT; SARCO ENDOPLASMIC RETICULUM CALCIUM ATPASE ISOFORM 2; THAPSIGARGIN; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CELL ADHESION; CELL JUNCTION; CELL MEMBRANE; CONTROLLED STUDY; DARIER DISEASE; DESMOSOME; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

1-DEOXYNOJIRIMYCIN; ADHERENS JUNCTIONS; BETA CATENIN; CADHERINS; CALCIUM; CELL ADHESION; CELLS, CULTURED; DARIER DISEASE; DESMOSOMES; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; FEMALE; HUMANS; KERATINOCYTES; MALE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN;

EID: 84902549600     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.8     Document Type: Article

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