Over-expression of hypoxia-inducible factor-1 alpha in vitro protects the cardiac fibroblasts from hypoxia-induced apoptosis

Journal of Cardiovascular Medicine

Volumn 15, Issue 7, 2014, Pages 579-586

  Yang, Baofeng ^a   He, Kaiwen ^b   Zheng, Fangfang ^b   Wan, Lin ^b   Yu, Xiangru ^b   Wang, Xuelian ^b   Zhao, Dan ^b   Bai, Yunlong ^b   Chu, Wenfeng ^b   Sun, Yan ^c   Lu, Yanjie ^b  

^a DAQING OILFIELD CO LTD   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; cardiac fibroblasts; HIF 1a; hypoxia

Indexed keywords

CALCIUM; CASPASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN BAX; PROTEIN BCL 2; DNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL HYPOXIA; CELL NUCLEUS; CELL PROTECTION; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; FIBROBLAST; GENE OVEREXPRESSION; HEART MUSCLE CELL; IN VITRO STUDY; NEWBORN; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE ISCHEMIA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CASPASE 3; CELL SURVIVAL; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IN SITU NICK-END LABELING; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; RATS; SIGNAL TRANSDUCTION;

EID: 84902549444     PISSN: 15582027     EISSN: 15582035     Source Type: Journal    
DOI: 10.2459/JCM.0b013e3283629c52     Document Type: Article

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