Disturbed anterior prefrontal control of the mesolimbic reward system and increased impulsivity in bipolar disorder

Neuropsychopharmacology

Volumn 39, Issue 8, 2014, Pages 1914-1923

  Trost, Sarah ^a   Diekhof, Esther Kristina ^a,b   Zvonik, Kerstin ^a   Lewandowski, Mirjana ^a   Usher, Juliana ^a   Keil, Maria ^a   Zilles, David ^a   Falkai, Peter ^a   Dechent, Peter ^c   Gruber, Oliver ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANHEDONIA; ARTICLE; BIPOLAR I DISORDER; BRAIN REGION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMPULSIVENESS; LIMBIC SYSTEM; MALE; NERVE POTENTIAL; PREFRONTAL CORTEX; PRIORITY JOURNAL; REWARD; BIPOLAR DISORDER; BRAIN MAPPING; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; YOUNG ADULT;

ADULT; BIPOLAR DISORDER; BRAIN MAPPING; FEMALE; HUMANS; IMPULSIVE BEHAVIOR; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PREFRONTAL CORTEX; REWARD; VENTRAL STRIATUM; YOUNG ADULT;

EID: 84902548735     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.39     Document Type: Article

References (48)

1. Abler B, Erk S, Walter H (2007). Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study. Psychopharmacology (Berl) 191: 823-833.
2. Abler B, Greenhouse I, Ongur D, Walter H, Heckers S (2008). Abnormal reward system activation in mania. Neuropsychopharmacology 33: 2217-2227.
3. Alloy LB, Bender RE, Whitehouse WG, Wagner CA, Liu RT, Grant DA et al (2012). High Behavioral Approach System (BAS) sensitivity, reward responsiveness, and goal-striving predict first onset of bipolar spectrum disorders: A prospective behavioral high-risk design. J Abnorm Psychol 121: 339-351.
4. Belger A, Puce A, Krystal JH, Gore JC, Goldman-Rakic P, McCarthy G (1998). Dissociation of mnemonic and perceptual processes during spatial and nonspatial working memory using fMRI. Hum Brain Mapp 6: 14-32.
5. Bermpohl F, Kahnt T, Dalanay U, Hägele C, Sajonz B, Wegner T et al (2010). Altered representation of expected value in the orbitofrontal cortex in mania. Hum Brain Mapp 31: 958-969.
6. Brambilla P, Bellani M, Yeh P-H, Soares JC, Tansella M (2009). White matter connectivity in bipolar disorder. Int Rev Psychiatry 21: 380-386.
7. Caseras X, Lawrence NS, Murphy K, Wise RG, Phillips ML (2013). Ventral striatum activity in response to reward: differences between bipolar I and II disorders. Am J Psychiatry 170: 533-541.
8. Dickstein DP, Finger EC, Skup M, Pine DS, Blair JR, Leibenluft E (2010). Altered neural function in pediatric bipolar disorder during reversal learning. Bipolar Disord 12: 707-719.
9. Diekhof EK, Falkai P, Gruber O (2008). Functional neuroimaging of reward processing and decision-making: a review of aberrant motivational and affective processing in addiction and mood disorders. Brain Res Rev 59: 164-184.
10. Diekhof EK, Gruber O (2010). When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires. J Neurosci 30: 1488-1493.
11. Diekhof EK, Keil M, Obst KU, Henseler I, Dechent P, Falkai P et al (2012a). A functional neuroimaging study assessing gender differences in the neural mechanisms underlying the ability to resist impulsive desires. Brain Res 1473: 63-77.
12. Diekhof EK, Nerenberg L, Falkai P, Dechent P, Baudewig J, Gruber O (2012b). Impulsive personality and the ability to resist immediate reward: an fMRI study examining interindividual differences in the neural mechanisms underlying self-control. Hum Brain Mapp 33: 2768-2784.
13. Forbes EE, Hariri AR, Martin SL, Silk JS, Moyles DL, Fisher PM et al (2009). Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder. Am J Psychiatry 166: 64-73.
14. Frantom LV, Allen DN, Cross CL (2008). Neurocognitive endophenotypes for bipolar disorder. Bipolar Disord 10: 387-399.
15. Friston KJ, Buechel C, Fink GR, Morris J, Rolls E, Dolan RJ (1997). Psychophysiological and modulatory interactions in neuroimaging. Neuroimage 6: 218-229.
16. Gorrindo T, Blair RJR, Budhani S, Dickstein DP, Pine DS, Leibenluft E (2005). Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder. Am J Psychiatry 162: 1975-1977.
17. Gruber J (2011). A review and synthesis of positive emotion and reward disturbance in bipolar disorder. Clin Psychol Psychother 18: 356-365.
18. Gruber O, von Cramon DY (2001). Domain-specific distribution of working memory processes along human prefrontal and parietal cortices: a functional magnetic resonance imaging study. Neurosci Lett 297: 29-32.
19. Guitart-Masip M, Huys QJM, Fuentemilla L, Dayan P, Duzel E, Dolan RJ (2012). Go and no-go learning in reward and punishment: Interactions between affect and effect. Neuroimage 62: 154-166.
20. Hafeman DM, Chang KD, Garrett AS, Sanders EM, Phillips ML (2012). Effects of medication on neuroimaging findings in bipolar disorder: an updated review. Bipolar Disord 14: 375-410.
21. Hasler G (2006). Evaluating endophenotypes for psychiatric disorders. Rev Bras Psiquiatr 28: 91-92.
22. Heng S, Song AW, Sim K (2010). White matter abnormalities in bipolar disorder: insights from diffusion tensor imaging studies. J Neural Transm 117: 639-654.
23. Horn NR, Dolan M, Elliott R, Deakin JFW, Woodruff PWR (2003). Response inhibition and impulsivity: an fMRI study. Neuropsychologia 41: 1959-1966.
24. Johnson SL, Carver CS, Gotlib IH (2012a). Elevated ambitions for fame among persons diagnosed with bipolar I disorder. J Abnorm Psychol 121: 602-609.
25. Johnson SL, Edge MD, Holmes MK, Carver CS (2012b). The behavioral activation system and mania. Annu Rev Clin Psychol 8: 243-267.
26. Juckel G, Schlagenhauf F, Koslowski M, Filonov D, Wüstenberg T, Villringer A et al (2006). Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics. Psychopharmacology (Berl) 187: 222-228.
27. Keedwell PA, Andrew C, Williams SCR, Brammer MJ, Phillips ML (2005). The neural correlates of anhedonia in major depressive disorder. Biol Psychiatry 58: 843-853.
28. Knutson B, Fong GW, Adams CM, Varner JL, Hommer D (2001). Dissociation of reward anticipation and outcome with eventrelated fMRI. Neuroreport 12: 3683-3687.
29. Lera-Miguel S, Andrés-Perpiñá S, Calvo R, Fatjó-Vilas M, Fañanás L, Lourdes F et al (2011). Early-onset bipolar disorder: how about visual-spatial skills and executive functions? Eur Arch Psychiatry Clin Neurosci 261: 195-203.
30. Linke J, King AV, Rietschel M, Strohmaier J, Hennerici M, Gass A et al (2012). Increased medial orbitofrontal and amygdala activation: evidence for a systems-level endophenotype of bipolar I disorder. Am J Psychiatry 169: 316-325.
31. Liu X, Hairston J, Schrier M, Fan J (2011). Common and distinct networks underlying reward valence and processing stages: a meta-analysis of functional neuroimaging studies. Neurosci Biobehav Rev 35: 1219-1236.
32. McClure SM, York MK, Montague PR (2004). The neural substrates of reward processing in humans: the modern role of FMRI. Neuroscientist 10: 260-268.
33. McDonald C, Bullmore ET, Sham PC, Chitnis X, Wickham H, Bramon E et al (2004). Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Arch Gen Psychiatry 61: 974-984.
34. Mohr HM, Goebel R, Linden DEJ (2006). Content- and task-specific dissociations of frontal activity during maintenance and manipulation in visual working memory. J Neurosci 26: 4465-4471.
35. Nusslock R, Almeida JR, Forbes EE, Versace A, Frank E, Labarbara EJ et al (2012). Waiting to win: elevated striatal and orbitofrontal cortical activity during reward anticipation in euthymic bipolar disorder adults. Bipolar Disord 14: 249-260.
36. O'Doherty JP (2004). Reward representations and reward-related learning in the human brain: insights from neuroimaging. Curr Opin Neurobiol 14: 769-776.
37. O'Sullivan N, Szczepanowski R, El-Deredy W, Mason L, Bentall RP (2011). fMRI evidence of a relationship between hypomania and both increased goal-sensitivity and positive outcome-expectancy bias. Neuropsychologia 49: 2825-2835.
38. Pan Y-J, Hsieh MH, Liu S-K (2011). Visuospatial working memory deficits in remitted patients with bipolar disorder: susceptibility to the effects of GABAergic agonists. Bipolar Disord 13: 365-376.
39. Pizzagalli DA, Goetz E, Ostacher M, Iosifescu DV, Perlis RH (2008). Euthymic patients with bipolar disorder show decreased reward learning in a probabilistic reward task. Biol Psychiatry 64: 162-168.
40. Pizzagalli DA, Holmes AJ, Dillon DG, Goetz EL, Birk JL, Bogdan R et al (2009). Reduced caudate and nucleus accumbens response to rewards in unmedicated subjects with major depressive disorder. Am J Psychiatry 166: 702-710.
41. Robinson OJ, Cools R, Carlisi CO, Sahakian BJ, Drevets WC (2012). Ventral striatum response during reward and punishment reversal learning in unmedicated major depressive disorder. Am J Psychiatry 169: 152-159.
42. Sala JB, Rämä P, Courtney SM (2003). Functional topography of a distributed neural system for spatial and nonspatial information maintenance in working memory. Neuropsychologia 41: 341-356.
43. Strakowski SM, Adler CM, Almeida J, Altshuler LL, Blumberg HP, Chang KD et al (2012). The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar Disord 14: 313-325.
44. Strakowski SM, Fleck DE, DelBello MP, Adler CM, Shear PK, Kotwal R et al (2010). Impulsivity across the course of bipolar disorder. Bipolar Disord 12: 285-297.
45. Swann AC (2010). Mechanisms of impulsivity in bipolar disorder and related illness. Epidemiol Psichiatr Soc 19: 120-130.
46. Swann AC, Lijffijt M, Lane SD, Steinberg JL, Moeller FG (2009). Increased trait-like impulsivity and course of illness in bipolar disorder. Bipolar Disord 11: 280-288.
47. Townsend JD, Bookheimer SY, Foland-Ross LC, Moody TD, Eisenberger NI, Fischer JS et al (2012). Deficits in inferior frontal cortex activation in euthymic bipolar disorder patients during a response inhibition task. Bipolar Disord 14: 442-450.
48. Williams JR (2008). The Declaration of Helsinki and public health. Bull World Health Organ 86: 650-652.