Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study

Psychopharmacology

Volumn 191, Issue 3, 2007, Pages 823-833

  Abler, Birgit ^a   Erk, Susanne ^b   Walter, Henrik ^b  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Dopaminergic reward system; Healthy subjects; Hypercapnia; Incentive salience; Olanzapine; Pharmaco fMRI

Indexed keywords

OLANZAPINE; PLACEBO;

ADULT; ARTICLE; BRAIN FUNCTION; BREATH HOLDING; CINGULATE GYRUS; CLINICAL TRIAL; CONCENTRATION LOSS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORPUS STRIATUM; CROSSOVER PROCEDURE; DIZZINESS; DOPAMINERGIC ACTIVITY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; EVENT RELATED POTENTIAL; FATIGUE; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEADACHE; HUMAN; HUMAN EXPERIMENT; MALE; NEUROIMAGING; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REACTION TIME; REWARD; SINGLE DRUG DOSE; TASK PERFORMANCE;

ANTIPSYCHOTIC AGENTS; BASAL GANGLIA; BENZODIAZEPINES; BRAIN; CEREBROVASCULAR CIRCULATION; CROSS-OVER STUDIES; DOPAMINE; DOUBLE-BLIND METHOD; HUMANS; HYPERCAPNIA; MAGNETIC RESONANCE IMAGING; MOTIVATION; OXYGEN; OXYGEN CONSUMPTION; PILOT PROJECTS; PREFRONTAL CORTEX; REACTION TIME; REFERENCE VALUES; REWARD; SEROTONIN UPTAKE INHIBITORS;

EID: 33847615250     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-006-0690-y     Document Type: Article

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