SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 14, 2014, Pages 3137-3141

Pharmacophore based virtual screening, molecular docking and biological evaluation to identify novel PDE5 inhibitors with vasodilatory activity

(6) Mittal, Anupama a Paliwal, Sarvesh a Sharma, Mukta a Singh, Aarti a Sharma, Swapnil a Yadav, Divya a

a BANASTHALI UNIVERSITY (India)

Author keywords

Cyclic adenosine monophosphate; Cyclic guanosine monophosphate; Discovery studio; Hydrogen bond acceptor; Phosphodiesterase 5

Indexed keywords

NSC 1012; NSC 1015; NSC 22; NSC 412; NSC 619; NSC 960; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG; VASODILATOR AGENT; PHOSPHODIESTERASE V;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; EXPERIMENTAL CARDIOVASCULAR DISEASE; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR INTERACTION; NONHUMAN; PHARMACOPHORE; RAT; VASCULAR RING; VIRTUAL REALITY; VIRTUAL SCREENING; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VASODILATATION; ANIMAL TISSUE; AORTA; CRYSTAL STRUCTURE; DATA BASE; DRUG CONFORMATION; DRUG STRUCTURE; ENZYME INHIBITOR INTERACTION; EXPERIMENTAL MODEL; IC50;

CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 5; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PHOSPHODIESTERASE 5 INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATION; VASODILATOR AGENTS;

RATTUS;

EID: 84902546922 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.05.004 Document Type: Article

Times cited : (32)

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