Application of cyclodextrin-based eluents in hydrophobic charge-induction chromatography: Elution of antibody at neutral pH

Journal of Chromatography A

Volumn 1352, Issue , 2014, Pages 62-68

  Ren, Jun ^a   Yao, Peng ^a   Cao, Yaming ^a   Cao, Jian ^a   Zhang, Lijun ^a   Wang, Yuanqiang ^a   Jia, Lingyun ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Competitive elution; Cyclodextrin; Host guest interaction; Hydrophobic charge induction chromatography; Immunoglobulin G

Indexed keywords

CYCLODEXTRINS; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; PH;

ACIDIC CONDITIONS; ANTIBODY PURIFICATION; COMPETITIVE ELUTIONS; HOST GUEST INTERACTIONS; HYDROPHOBIC CHARGE-INDUCTION CHROMATOGRAPHIES; IMMUNOGLOBULIN G; INCLUSION COMPLEX; PROTEIN A CHROMATOGRAPHY;

ANTIBODIES;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 4 MERCAPTOETHYLPYRIDINE; ALPHA CYCLODEXTRIN; BETA CYCLODEXTRIN; GAMMA CYCLODEXTRIN; IMMUNOGLOBULIN G; PYRIDINE; UNCLASSIFIED DRUG;

ADSORPTION KINETICS; ARTICLE; BINDING AFFINITY; CHROMATOGRAPHY; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELUTION; HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY; INTERMETHOD COMPARISON; IONIC STRENGTH; MOLECULAR DOCKING; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL; PROCESS DEVELOPMENT; SEPARATION TECHNIQUE;

COMPETITIVE ELUTION; CYCLODEXTRIN; HOST-GUEST INTERACTION; HYDROPHOBIC CHARGE-INDUCTION CHROMATOGRAPHY; IMMUNOGLOBULIN G;

CHROMATOGRAPHY; CYCLODEXTRINS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNOGLOBULIN G; LIGANDS; PYRIDINES;

EID: 84902545131     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.05.060     Document Type: Article

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