Complement component C3 activation: The leading cause of the prozone phenomenon affecting HLA antibody detection on single-antigen beads

Transplantation

Volumn 97, Issue 12, 2014, Pages 1279-1285

  Schwaiger, Elisabeth ^a   Wahrmann, Markus ^a   Bond, Gregor ^a   Eskandary, Farsad ^a   Böhmig, Georg A ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

C3; Complement; HLA antibodies; Prozone effect; Single antigen flow beads

Indexed keywords

COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3 ANTIBODY; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4 ANTIBODY; DITHIOTHREITOL; EDETIC ACID; HLA ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; METHYLAMINE; SNAKE VENOM; UNCLASSIFIED DRUG;

ALLOIMMUNITY; ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ARTICLE; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; COMPLEX FORMATION; CONTROLLED STUDY; DILUTION; FALSE NEGATIVE RESULT; FLUORESCENCE; HEAT; HUMAN; INCIDENCE; PRIORITY JOURNAL; PROZONE; SENSITIZATION; SINGLE ANTIGEN FLOW BEAD;

ANTIBODIES; ARTIFACTS; BIOLOGICAL MARKERS; COMPLEMENT ACTIVATION; COMPLEMENT C1; COMPLEMENT C3; FEMALE; HISTOCOMPATIBILITY; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; MALE; MIDDLE AGED; ORGAN TRANSPLANTATION; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS;

EID: 84902544561     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000441091.47464.c6     Document Type: Article

References (14)

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