Post-transcriptional regulation by miR-137 underlies the low abundance of CAR and low rate of bilirubin clearance in neonatal mice

Life Sciences

Volumn 107, Issue 1-2, 2014, Pages 8-13

  Chen, Sheng ^a   He, Nianhai ^a   Yu, Jialin ^b   Li, Luquan ^b   Hu, Ying ^a   Deng, Rui ^a   Zhong, Shiming ^a   Shen, Leilei ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Androstane receptor (CAR); Bilirubin clearance; Hypomethylation; Jaundice; miR 137; Neonatal hyperbilirubinemia

Indexed keywords

BILIRUBIN; CONSTITUTIVE ANDROSTANE RECEPTOR; MICRORNA; MIRNA 137; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE CONTROL; GENE EXPRESSION; LIVER CELL; MALE; MOUSE; NEONATAL HYPERBILIRUBINEMIA; NEWBORN; NONHUMAN; OBSTRUCTIVE JAUNDICE; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPRESSOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA METHYLATION; WESTERN BLOTTING;

ANDROSTANE RECEPTOR (CAR); BILIRUBIN CLEARANCE; HYPOMETHYLATION; JAUNDICE; MIR-137; NEONATAL HYPERBILIRUBINEMIA;

ANIMALS; ANIMALS, NEWBORN; BILIRUBIN; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTES; MALE; MICE; MICE, INBRED BALB C; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

EID: 84902544403     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.04.024     Document Type: Article

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